CAS: 9013-34-7; Deae-Cellulose

该化合物是一种改良的纤维素,其特点是与纤维素脊椎相连的二乙基乙基组,这种改变具有交换性,使DEDEE-纤维素成为生物化学应用中的宝贵材料,特别是在蛋白净化和染色体学中,它通常被用作固定阶段,用于电离交换色谱,因为它能够在特定pH条件下与积极充电的分子,如蛋白质和核酸相互作用.DEDEE-纤维素具有高表面积,稳定性和生物兼容性,可以用于各种生物和制药工艺,一般具有不同的粒子大小和替代程度,可以影响其结合能力和选择性.此外,DEE-纤维素经常用于生物化学和分子生物学领域的研究和工业环境,成为生物化学和分子生物学领域的基本工具.

结构式图片

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-2010304368-A1
    优先权日:2006-09-20
    标 题:Components and method for enzymatic synthesis of nucleic acids
    发明人:CHERKASOV DMITRY; BAEUML ENGLEBERT; BAEUML ELISABETH
    权利人:CHERKASOV DMITRY; BAEUML ENGLEBERT; BAEUML ELISABETH
    摘要:Novel methods for enzymatic synthesis of nucleic acid chains and the substrates for the same are disclosed. The methods are based on a step-wise enzymatic reaction. The sequencing of nucleic acids is an example of the use of the claimed methods.

    专利号:US-6217857-B1
    优先权日:1989-06-28
    标题 :Cytokine synthesis inhibitory factor (IL-10) and pharmaceutical compositions thereof
    发明人:MOSMANN TIMOTHY R; MOORE KEVIN W; BOND MARTHA W; VIEIRA PAULO J M
    权利人:SCHERING CORP
    摘要:Mammalian genes and proteins, designated cytokine synthesis inhibitory factors (CSIF's, now known as Interleukin-10 (IL-10)), are provided which are capable of inhibiting the synthesis of cytokines associated with delayed type hypersensitivity responses, and which, together with antagonists, are useful in treating diseases associated with cytokine imbalances, such as leishmaniasis and other parasitic infections, and certain immune disorders including MHC associated autoimmune diseases caused by excessive production of interferon-gamma.

    专利号:US-5231012-A
    优先权日:1989-06-28
    标 题:Nucleic acids encoding cytokine synthesis inhibitory factor (interleukin-10)
    发明人:MOSMANN TIMOTHY R; MOORE KEVIN W; BOND MARTHA W; VIEIRA PAULO J M
    权利人:SCHERING CORP
    摘要:Mammalian genes and proteins, designated cytokine synthesis inhibitory factors (CSIFs) (now known as interleukin -10), are provided which are capable of inhibiting the synthesis of cytokines associated with delayed type hypersensitivity responses, and which, together with antagonists, are useful in treating diseases associated with cytokine imbalances, such as leishmaniasis and other parasitic infections, and certain immune disorders including MHC associated autoimmune diseases caused by excessive production of interferon- gamma .

    专利号:EP-0567450-B1
    优先权日:1989-06-28
    标题 :Cytokine synthesis inhibitory factor and methods of using same
    发明人:MOSMANN TIMOTHY R; MOORE KEVIN W; BOND MARTHA W; VIEIRA PAULO J M
    权利人:SCHERING CORP
    摘要:Mammalian genes and proteins, designated cytokine synthesis inhibitory factors (CSIFs), are provided which are capable of inhibiting the synthesis of cytokines associated with delayed type hypersensitivity responses, and which, together with antagonists, are useful in treating diseases associated with cytokine imbalances, such as leishmaniasis and other parasitic infections, and certain immune disorders including MHC associated autoimmune diseases caused by excessive production of interferon- gamma .

    专利号:US-6750049-B1
    优先权日:1999-03-23
    标题 :Synthesis of 1,2,3,4-tetrahydroxybenzenes and 1,2,3-trihydroxybenzenes using myo-inositol-1-phosphate synthase and myo-inositol 2-dehydrogenase
    发明人:FROST JOHN W; HANSEN CHAD A
    权利人:UNIV MICHIGAN STATE
    摘要:A bioengineered synthesis scheme for the production of 1,2,3,4-tetrahydroxybenzene from a carbon source is provided. Methods of producing 1,2,3,4-tetrahydroxybenzene from a carbon source based on the synthesis scheme are also provided. Methods are also provided for converting 1,2,3,4-tetrahydroxybenzene to 1,2,3-trihydroxybenzene by catalytic hydrogenation.

    专利号:US-4710566-A
    优先权日:1984-12-27
    标题:Purification of the messenger RNA cap-binding protein
    发明人:KOZARICH JOHN W; RHOADS ROBERT E
    权利人:UNIV YALE
    摘要:The synthesis of a new affinity medium, the p-aminophenyl-γ-ester of 7-methylguanosine-5'-triphosphate coupled to Sepharose, for use in affinity chromatography is claimed. An improved method in terms of speed and purity for the isolation of messenger ribonucleic acid cap-binding protein is claimed. The synthesis of the p-aminophenyl-γ-ester of 7-methylguanosine-5'-triphosphate is described.
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    [参考文献]: Alessandra Olianas, Et Al. Striped Mullet (Mugil Cephalus) Hemoglobin System: Multiplicity And Functional Properties. J Comp Physiol B. 2011 Feb;181(2):187-97.
    [参考文献]: D Z Ma, Et Al. A Peptide With Potent Antifungal And Antiproliferative Activities From Nepalese Large Red Beans. Peptides. 2009 Dec;30(12):2089-94.
    [参考文献]: Edita Mazoniene, Et Al. Interaction Of Cellulose-Based Cationic Polyelectrolytes With Mucin. Colloids Surf B Biointerfaces. 2011 Mar;83(1):160-4.
    [参考文献]: Ines Maalej, Et Al. Highly Thermostable Xylanase Of The Thermophilic Fungus Talaromyces Thermophilus: Purification And Characterization. Appl Biochem Biotechnol. 2009 Jul;158(1):200-12.
    [参考文献]: Janez Anar, Et Al. Ni Speciation In Tea Infusions By Monolithic Chromatography--Icp-Ms And Q-Tof-Ms. Anal Bioanal Chem. 2013 Feb;405(6):2041-51.

    合成参考文献


    参考文献:10.1021/bi9616965
    摘要:Billger MA, Bhattacharjee G, Williams RC, Bhatacharjee G. Dynamic instability of microtubules assembled from microtubule-associated protein-free tubulin: neither variability of growth and shortening rates nor "rescue" requires microtubule-associated proteins. Biochemistry. 1996 Oct 22;35(42):13656–63. doi: 10.1021/bi9616965.
    参考文献:10.1042/ba20030122
    摘要:Reddy K RC, Srivastava PK, Dey PM, Kayastha AM. Immobilization of pigeonpea (Cajanus cajan) urease on DEAE-cellulose paper strips for urea estimation. Biotechnol Appl Biochem. 2004 Jun;39(Pt 3):323–7. doi: 10.1042/ba20030122.
    参考文献:10.1016/j.chemosphere.2006.04.049
    摘要:Akhtar S, Husain Q. Potential applications of immobilized bitter gourd (Momordica charantia) peroxidase in the removal of phenols from polluted water. Chemosphere. 2006 Nov;65(7):1228–35. doi: 10.1016/j.chemosphere.2006.04.049.
    参考文献:10.1074/jbc.m106962200
    摘要:Trent MS, Ribeiro AA, Doerrler WT, Lin S, Cotter RJ, Raetz CR. Accumulation of a polyisoprene-linked amino sugar in polymyxin-resistant Salmonella typhimurium and Escherichia coli: structural characterization and transfer to lipid A in the periplasm. J Biol Chem. 2001 Nov 16;276(46):43132–44. doi: 10.1074/jbc.m106962200.
    参考文献:10.1093/glycob/cwl016
    摘要:Matsushita-Oikawa H, Komatsu M, Iida-Tanaka N, Sakagami H, Kanamori T, Matsumoto I, Seno N, Ogawa H. Novel carbohydrate-binding activity of bovine liver beta-glucuronidase toward lactose/N-acetyllactosamine sequences. Glycobiology. 2006 Oct;16(10):891–901. doi: 10.1093/glycob/cwl016.
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