CAS: 1875-89-4; 2-(M-Tolyl)Ethanol

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CAS号766-82-5 间甲苯乙炔 | CAS号621-36-3 间甲苯乙酸 | CAS号53088-69-0 3-甲基苯乙酸甲酯 | CAS号40061-55-0 间甲苯乙酸乙酯 | CAS号75-21-8 环氧乙烷 | CAS号28987-79-3 间甲苯基溴化镁 | CAS号99-04-7 间甲基苯甲酸 | CAS号587-03-1 3-甲基苄醇 | CAS号5181-67-9 ethyl 3-methyl-... | CAS号29640-98-0 5-氟-2-硝基苯乙酸 | CAS号121-91-5 间苯二甲酸(IPA) | CAS号32504-15-7 (2-间甲苯乙基)-肼 | CAS号100-80-1 3-甲基苯乙烯 | CAS号16799-08-9 间甲基苯乙基溴 | CAS号137069-23-9 甲基-(2-间甲苯乙基)胺 | CAS号114686-67-8 1-(2-iodoethyl)... | CAS号72927-80-1 2-甲苯基乙醛 | CAS号51015-29-3 3,4-二氢化-6-甲基-1(... | CAS号51125-15-6 1-methyl-3-pent...

1-Methyl-3-(2-Phenylmethoxyethyl)Benzene置于1,3-二甲基脲,三(N,N-四亚甲基)磷酰胺,Lithium Bromide体系中,用 四氢呋喃 用作溶剂,以50%的收率获得3-甲基苯乙醇
参考文献:受锂离子电池化学启发的可扩展且安全的合成有机电解还原
标题:受锂离子电池化学启发的可扩展且安全的合成有机电解还原
摘要:大规模无钠桦木还原尽管条件艰巨,化学家仍经常使用所谓的桦木还原:将发火钠溶解在纯液氨中以实现芳烃的部分还原.彼得斯等人.研究并优化了小规模电化学替代方案,以设计出一种更安全的方案,可以在更大范围内使用各种功能复杂的底物.科学,本期第 14 页.838 优化的电化学条件比溶解在氨中的钠更安全地还原各种芳香族底物.还原电合成在复杂有机基质的大规模应用中面临着长期的挑战.在这里,我们展示了数十年对锂离子电池材料,电解质和添加剂的研究如何为实现 Birch 还原的实际可扩展的还原电合成条件提供灵感.具体来说,我们证明,使用牺牲阳极材料(镁或铝),结合廉价,无毒,水溶性质子源(二甲基脲)以及受电池技术[三(吡咯烷)磷酰胺]启发的过充电保护剂可以允许用于医药相关结构单元的多克规模合成.我们展示了这些条件如何相对于经典的电化学和化学溶解金属还原具有非常高水平的官能团耐受性.最后,我们证明相同的电化学条件可以应用于其他溶解金属型还原转化,包括
Doi:10.1126/science.Aav5606

专利信息

专利号:US-7342003-B2
优先权日:2001-10-25
标 题 :Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs
发明人：MOORMAN ALLAN R; SCANNELL MICHAEL; BALASUBRAMANIAN THIAGARAJAN; OUTCALT RUSSELL; LEUNG EDWARD
权利人:KING PHARMACEUTICALS RES & DEV
摘要:Provided is a method for the synthesis of an aralkyloxyadenosine or an alkoxyadenosine. The method includes protecting the hydroxyl sugar groups with a protecting group to produce a protected halogenated adenosine. The protected halogenated adenosine is alkoxylated, and the hydroxyl sugar groups of the protected halogenated adenosine are deprotected to provide the aralkyloxyadenosine or alkoxyadenosine.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-2006135466-A1
优先权日:2001-10-25
标题 :Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs

专利号:WO-2005033121-A2
优先权日:2003-10-03
标 题:Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs

专利号:US-7825149-B2
优先权日:2006-01-19
标 题 :Substituted imidazoles
发明人：CHUBB NATHAN ANTHONY LOGAN; COX MARK ROGER; DAUVERGNE JEROME SEBASTIEN; EWIN RICHARD ANDREW; LAURET CHRISTELLE
权利人:PFIZER LTD
摘要:This invention relates to a range of alpha substituted 2-benzyl substituted imidazole compounds and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes for their synthesis and their use as parasiticides.