CAS: 26523-64-8; 1,1,1-Trichloro-2,2,2-Trifluoroethane

该化合物是一种含有化学公式C2Cl3F3的氯氟烃(CFC),是一种无色,不易燃的室温液体,其特点是低温,低沸点和高挥发性;该化合物在工业应用中被广泛用作溶剂,特别是用于清洁电子部件和制冷剂;其物理特性包括与水相比密度相对较低,蒸气压力较高,有助于其作为溶剂的功效;然而,三氯三氟乙烷因其消耗臭氧潜能而闻名于世,由于环境方面的关切,导致其根据<蒙特利尔议定书>逐步淘汰;其大气寿命长,使之能到达平流层,并导致臭氧层消耗;其生产和使用在许多国家受到极大限制;安全考虑因素包括其可能导致呼吸刺激和作为人类致癌物的分类,因此有必要采取适当的处理和处置措施.

结构式图片

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-5654473-A
    优先权日:1995-03-16
    标题:Intermediates for the synthesis of trifluoromethylated organic compounds
    发明人:VAN DER PUY MICHAEL
    权利人:ALLIED SIGNAL INC
    摘要:Novel trifluoromethylated intermediates are provided which are useful in synthesizing trifluoromethylated organic compounds. Specifically, compounds of the formula CF 3 CClâ•?CHCH 2 X are provided, which compounds are versatile intermediates for the synthesis of a wide variety of trifluoromethylated organic compounds.

    专利号:US-8128902-B2
    优先权日:2011-04-12
    标题:Method for the synthesis of anhydrous hydrogen halide and anhydrous carbon dioxide
    发明人:TARANCON III GREGORIO
    权利人:TARANCON III GREGORIO; MIDWEST REFRIGERANTS LLC
    摘要:A method for the synthesis of anhydrous hydrogen halide fluids from organic halide fluids, such as perfluorocarbon fluids and refrigerant fluids, and anhydrous carbon dioxide for the environmentally safe disposition thereof.

    专利号:US-8043574-B1
    优先权日:2011-04-12
    标 题:Apparatus for the synthesis of anhydrous hydrogen halide and anhydrous carbon dioxide
    发明人:TARANCON III GREGORIO
    权利人:MIDWEST REFRIGERANTS LLC
    摘要:An apparatus for the synthesis of anhydrous hydrogen halide fluids from organic halide fluids, such as perfluorocarbon fluids and refrigerant fluids, and anhydrous carbon dioxide for the environmentally safe disposition thereof.

    专利号:US-10669160-B2
    优先权日:2018-04-30
    标题:Heterogeneous wet synthesis process for preparation of high purity tungsten pentahalide
    发明人:LIU YUMIN; LI FENG; WAN ZHIWEN; FAFARD CLAUDIA; WIESE STEFAN; HUSSON GUILLAUME; NIKIFOROV GRIGORY; SUI BIN; GIRARD JEAN-MARC
    权利人:AIR LIQUIDE; AIR LIQUIDE AMERICAN
    摘要:Synthesis of tungsten pentahalide compositions having low impurity profiles are disclosed. The specific impurity profile permits deposition of high purity tungsten-containing films using vapor deposition processes or other semiconductor manufacturing processes without introduction of performance-impacting contaminants.

    专利号:US-6111130-A
    优先权日:1998-05-14
    标题:Process for the preparation of trifluoromethyl containing derivatives
    发明人:VAN DER PUY MICHAEL
    权利人:ALLIED SIGNAL INC
    摘要:The present invention relates to a process for the preparation of trifluoromethylated derivatives of the formula CF 3 CClâ•?CHCH 2 OC(â•?O)R, wherein R is unsubstituted or substituted C 1 to C 6 straight chain or branched alkyl, unsubstituted or substituted C 3 to C 7 cycloalkyl, unsubstituted or substituted C 2 to C 12 alkenyl, a benzyl group unsubstituted or substituted with R', a phenyl group unsubstituted or substituted with R'; R' is an unsubstituted or substituted C 1 to C 6 straight chain or branched alkyl; and wherein where R and/or R' are substituted each is substituted with R', by reaction of HCFC-353 with carboxylic acid salts. The trifluoromethylated derivatives, particularly CF 3 CClâ•?CHCH 2 OC(â•?O)CH 3 , are versatile intermediates for the synthesis of a wide variety of trifluoromethylated organic compounds, which find utility as pharmaceuticals, agricultural chemicals, and materials such as liquid crystals.

    专利号:WO-8911473-A1
    优先权日:1988-05-27
    标 题:Process for the synthesis of o-substituted oxime compounds
    发明人:CHEMPOLIL THOMAS MATHEW
    权利人:ALLIED SIGNAL INC
    摘要:A novel process for the production of O-substituted oximes is disclosed. The process involves reacting an oxime with an alkali-metal hydroxide optionally in a solvent which forms an azeotrope with water to form a mixture of the alkali metal salt of the oxime and water, removing all or a portion of the water by distilling the mixture azeotropically and reacting the distilled mixture with an alpha halo carboxylic acid.
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    合成参考文献


    摘要:Łaźny, R.; Nodzewska, A., Science of Synthesis Knowledge Updates, (2012) 3, 474.
    摘要:Human Toxicology., 1(239), 1982 []
    摘要:Boudakian MM; Kirk-Othmer Encyclopedia of Chemical Technology (1999-2013). John Wiley & Sons, Inc. Fluorinated Aromatic Compounds. Online Posting Date: 4 Dec 2000
    摘要:U.S. Department of Health and Human Services, Public Health Service. Centers for Disease Control, National Institute for Occupational Safety and Health. NIOSH Manual of Analytical Methods, 3rd ed. Volumes 1 and 2 with 1985 supplement, and revisions. Washington, DC: U.S. Government Printing Office, February 1984., p. 1020-1
    摘要:Currance, P.L. Clements, B., Bronstein, A.C. (Eds).; Emergency Care For Hazardous Materials Exposure. 3Rd edition, Elsevier Mosby, St. Louis, MO 2005, p. 222
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