CAS: 5518-52-5; Tri(Furan-2-yl)Phosphine

上下游产品

furan 2-lithiofuran 2)Ag(tris(2-furyl)phosphine)3(ONO2) ethanolphosphonium bromidetri-2-furyl3-bromo-6-(4-diethylaminophenylazo)phenylphosphonium bromide methyl (E-3{(5R,6R,7S,8S)-6,7,8-tris(benzyloxy)-5-[(benzyloxy)methyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-yl}prop-2-enoate) methyl-tri(2-furyl)phosphonium iodide

呋喃-2-基-锂置于三氯化磷体系中,化学反应生成 三(2-呋喃基)膦
参考文献:Triethylborane-Mediated Hydrogallation And Hydroindation: Novel Access To Organogalliums And Organoindiums
标题:Triethylborane-Mediated Hydrogallation And Hydroindation: Novel Access To Organogalliums And Organoindiums
摘要:Hydrogallation Of Carbon-Carbon Multiple Bonds Proceeds In The Presence Of Triethylborane As A Radical Initiator. Several Functionalities Do Not Interfere With This Reaction. Resulting Alkenyl-And Alkylgallium Species Can Be Trapped By Several Electrophiles. Highly Regioselective Radical Addition Of An Indium Hydride Reagent To Alkynes Is Also Achieved. Various Functionalities Are Tolerant Under The Reaction Conditions. The Reaction Proceeds With Complete Anti Stereoselectivity. Alkenylindiums Obtained Via Hydroindation Can Be Employed For The Following Cross-Coupling Reaction With Aryl Halides In One Pot.
DOI:10.1021/jo0344790

专利信息

专利号:US-9242925-B2
优先权日:2011-08-29
标题:Versatile and stereospecific synthesis of γ,δ-unsaturated amino acids by Wittig reaction
发明人：JUGE SYLVAIN; BAYARDON JEROME; REMOND EMMANUELLE; ONDEL-EYMIN MARIE-JOELLE
权利人:JUGE SYLVAIN; BAYARDON JEROME; REMOND EMMANUELLE; ONDEL-EYMIN MARIE-JOELLE; CENTRE NAT RECH SCIENT; UNIV BOURGOGNE
摘要:The γ,δ-unsaturated α-amino acids of general formula (I). Also, a versatile process for the stereospecific synthesis of said compounds of formula (I), involving a Wittig reaction. Further, intermediate products of general formulae (II) and (III), as shown below, which are involved in the synthesis of compounds (I). n n n n n n n n n n n n Compounds of general formula (I) may be useful as therapeutic substances, or as reagents or intermediates for fine chemistry.

专利号:US-2023286918-A1
优先权日:2020-07-02
标 题:Manufacturing process for 3,5-dichloropicolinonitrile for synthesis of vadadustat
发明人：JURKAUSKAS VALDAS; JUNG YOUNG CHUN; KWON TAESOO; KANNAN ARUNACHALAM; GONDI VIJAYA BHASKER
权利人:AKEBIA THERAPEUTICS INC
摘要:Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the synthesis of vadadustat.

专利号:US-5684130-A
优先权日:1995-06-05
标题 :Process for synthesis of organic compounds using magnetic particles
发明人：SUCHOLEIKI IRVING
权利人:SOLID PHASE SCIENCES CORP
摘要:This invention provides a process for the synthesis of a defined chemical entity, i.e., any desired chemical compound, in high yield using a solid support comprising a magnetic particle, in organic solvents. In general, a sequence of chemical synthetic steps are required to prepare the defined chemical entity bound to the particle. The particle comprises a resin bearing a high concentration of substituent pendant functional groups, to which the first reagent employed in the synthetic sequence binds; in subsequent reaction steps further reagents react with the growing chemical intermediate bound to the pendant functional groups until the defined chemical entity is obtained. The particle also comprises smaller paramagnetic or superpara-magnetic particles incorporated within the resin. The magnetic particle therefore responds to imposed magnetic field gradients, permitting ease of manipulation in steps involving removal of organic solvent.

专利号:US-7208607-B1
优先权日:2003-11-19
标 题 :Process for synthesis of perindopril and pharmaceutically acceptable salts thereof
发明人：DUBUFFET THIERRY; LANGLOIS PASCAL
权利人:SERVIER LAB
摘要:Process for the synthesis of perindopril of formula (I): n nand pharmaceutically acceptable salts thereof.

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-11718584-B2
优先权日:2019-02-22
标题 :Process for the synthesis anthranilic diamide compounds and intermediates thereof
发明人：KARRI PHANEENDRASAI; PABBA JAGADISH; SHINDE BHARAT UTTAMRAO; KALWAGHE AMOL DNYANESHWAR; MADHAVRAO KAMBLE MARUTI; KLAUSENER ALEXANDER G M; PANMAND DEEPAK SHANKAR
权利人:PI INDUSTRIES LTD
摘要:The present invention disclosed a process for the synthesis of anthranilic diamide compound of formula (I), n n n n n n n n n n wherein, R 1 , R 2 , R 3a , R 3b , R 3c , R 4 , R 5 , R 6 and Z are as defined in the detailed description. The process comprising the step of obtaining a mono- or dicyano substituted aniline compound of formula (IV) which is then converted to an anthranilic acid compound of formula (V) or an anthranilic amide compound of formula (Va). Further, the compound of formula (VI) can be optionally synthesized from compound of formula (IV or V or Va)