CAS: 92339-07-6; 2,3,5,6-Tetrafluoro-1,4-Benzenedimethanol

• 英文名称2,3,5,6-Tetrafluoro-1,4-Benzenedimethanol
• 中文名称2,3,5,6-四氟对苯二甲醇
• IUPAC名称(perfluoro-1,4-phenylene)dimethanol
• 其它别名2,3,5,6-四氟-1,4-对苯二甲醇; Tetrafluoro-4-[(Hydroxymethyl)Phenyl]Methanol
• CAS编号92339-07-6
• MFCD编号:MFCD00229147
• EINECS号:814-676-7
• 分子式:C8H6F4O2
• 分子量:210.13
• 产品CID: 1961226
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• InChIKey: SDHKGYDQOGCLQM-UHFFFAOYSA-N
• InChI=1S/C8H6F4O2/c9-5-3(1-13)6(10)8(12)4(2-14)7(5)11/h13-14H,1-2H2…
• 计算化学: 氢键受体数2.0氢键供体数2.0可旋转键数2.0

物理性质

• 熔点127.0-131.0 °C
• 沸点256.0±35.0 °C at 760 mmHg
• 闪点108.6±25.9 °C
• 密度1.6±0.1 g/cm3
• pKa:12.55±0.10(预测)
• PSA:40.46
• LogP:1.2276
• 折射率1.496
• 蒸汽压0.0±0.5 mmHg at 25°C
• 外观形态淡黄色晶体
• 储存条件密封, 常温干燥保存
• 产品应用该化合物是合成四氟苯基甲状腺素和七氟苯甲状菌甲状体的重要起始材料.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2A
  急性毒性 类别4(经口)
  严重眼刺激 类别2
• 警示词Warning(警告)
• 危险描述H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H302 |吞咽有害.
• 防范说明P233-P260-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
• UN编号UN 2811 6.1/PG 3
• 危险品标志Xn
• 安全声明S22-S24/25-S61-S36/37
• 危险类别码R68,R20/21/22,R40,R52/53
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 15041-74-4 = 92339-07-6
  反应条件:1.1 Reagents: Tetrabutylammonium Chloride,Zinc Chloride,Sodium Borohydride Solvents: Tetrahydrofuran; Rt1.2 Solvents: Tetrahydrofuran; Rt -> Reflux; 8 H,Reflux
  标题:Synthesis Of 4-Methyl-2,3,5,6-Tetrafluorobenzyl Alcohol
  作者:Yuan,Qi-Liang; Qian,Jie; Shi,Zheng-Jun; Bao,Zhang-Feng; Zeng,Jun
  参考文献:Huaxue Shijie 日期:2014 卷标:55(5) 页码:285-288]
  
  15041-74-4 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Borohydride Catalysts: Tetrabutylammonium Chloride,Aluminum Chloride Solvents: Tetrahydrofuran; Rt; Rt -> Reflux; 8 H,Reflux; Reflux -> Rt1.2 Reagents: Hydrochloric Acid Solvents: Water
  标题:Research On Synthesis Of 2,3,5,6-Tetrafluoro-4-Methoxyl Methyl Benzyl Alcohol
  作者:Yuan,Qiliang; Shi,Zhengjun; Qian,Jie; Zhang,Jiabing; Chen,Haifeng
  参考文献:Huagong Shengchan Yu Jishu 日期:2013 卷标:20(6) 页码:11-14]
  
  727-55-9 = 92339-07-6
  反应条件:1.1 Reagents: Calcium Chloride Solvents: Ethanol,Water; 30 Min,15 °C1.2 Reagents: Potassium Tetrafluoroborate; 2 H,15 °C
  标题:Method For Preparation Of Tetrafluoro-P-Phenylenedimethanol With Reduced Waste Discharge Using Calcium Chloride
  参考文献:China]
  
  652-36-8 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: 1,2-Dimethoxyethane; 1 H,50 °C; 7 H,60 °C1.2 Solvents: Toluene; 60 °C -> 50 °C1.3 Reagents: Hydrochloric Acid Solvents: Water; 1 H,50 °C; 6 H,60 °C
  标题:Process For Preparation Of 4-Methyl-2,3,5,6-Tetrafluorobenzyl Alcohol
  参考文献:World Intellectual Property Organization]
  
  652-36-8 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: 1,2-Dimethoxyethane; Rt -> 50 °C; 1 H,50 °C; 7 H,60 °C1.2 Solvents: Ethanol; 60 °C -> 50 °C1.3 Reagents: Hydrochloric Acid Solvents: Water; 6 H,60 °C
  标题:Method For Producing Halogen-Substituted Benzenedimethanols
  参考文献:World Intellectual Property Organization]
  
  727-55-9 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: Tetrahydrofuran; Rt1.2 Reagents: Hydrochloric Acid Solvents: Tetrahydrofuran,Water; 5 H,Rt; 2 H,25 - 30 °C
  标题:Process For Production Of Halogen-Substituted Benzenedimethanol
  参考文献:World Intellectual Property Organization]
  
  727-55-9 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: Tetrahydrofuran; 30 Min,Reflux; 3 H,Reflux; 7 H,Reflux1.2 Reagents: Sulfuric Acid Solvents: Water; Neutralized
  标题:Synthesis Of "Black Hole" 4,4'-Bipyridinium Cyclophane
  作者:Xi,Hai-Tao; Sun,Xiao-Qiang; Wei,Hai-Lin; Meng,Qi; Pan,Yi; Et Al
  参考文献:Youji Huaxue 日期:2007 卷标:27(12) 页码:1547-1551]
  
  652-36-8 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Hydride Solvents: Tetrahydrofuran; Rt -> 65 °C1.2 Solvents: Water; 3 H,65 °C; 2 H,65 °C1.3 Reagents: Hydrochloric Acid Solvents: Water; 30 Min,25 - 30 °C
  标题:Method For Producing Halogen-Substituted Benzenedimethanol
  参考文献:World Intellectual Property Organization]
  
  727-55-9 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: Ethanol; 5 H,50 °C1.2 Reagents: Hydrochloric Acid Solvents: Water
  标题:Preparation Of 2,3,5,6-Tetrafluoro-1,4-Benzenedimethanol As Intermediate For Pyrethroids
  参考文献:World Intellectual Property Organization]
  
  652-36-8 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: Methanol; 5 H,50 °C
  标题:Novel Process For The Preparation Of [2,3,5,6-Tetrafluoro-4-(Methoxymethyl)Phenyl]Methyl 2,2,3,3-Tetramethylcyclopropanecarboxylate
  参考文献:China]
  
  15041-74-4 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: Tetrahydrofuran; 6 H,85 °C1.2 Reagents: Hydrochloric Acid Solvents: Water
  标题:Preparation Of 2,3,5,6-Tetrafluoro-1,4-Benzenedimethanol From 2,3,5,6-Tetrafluoro-1,4-Benzenedicarbonyl Dichloride
  参考文献:China]
  
  15041-74-4 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: Chlorobenzene; 0.5 H,70 °C1.2 Catalysts: Iodine Solvents: Chlorobenzene; 0.5 H,70 °C; 7 H,70 °C; 70 °C -> 50 °C1.3 Reagents: Hydrochloric Acid Solvents: Water; 50 °C; 0.5 H,Ph 1 - 2,50 °C1.4 Reagents: Sodium Hydroxide Solvents: Water; Ph 8 - 9
  标题:A Process For Preparing 2,3,5,6-Tetrafluoro-1,4-Benzenedimethanol
  参考文献:China]
  
  7154-26-9 = 92339-07-6
  反应条件:1.1 Reagents: Hydrofluoric Acid Solvents: Dimethylformamide; 7 H,120 °C
  标题:Preparation Of 2,3,5,6-Tetrafluoro-Terephthalic Alcohol
  参考文献:China]
  
  652-36-8 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: 1,2-Dimethoxyethane1.2 Reagents: Dimethyl Sulfate Solvents: Toluene
  标题:Process For The Preparation Of Halogen-Substituted Dibenzyl Alcohols By The One-Step Reduction Of The Corresponding Halogen-Substituted Terephthalic Acids Using Sodium Boranates And Alkylation Agents
  参考文献:European Patent Organization]
  
  89992-50-7 = 92339-07-6
  反应条件:1.1 Solvents: Acetic Acid,Water1.2 Reagents: Sodium Nitrite Solvents: Water1.3 Reagents: Sodium Hydroxide Solvents: Water
  标题:Preparation Of 4-Methyl-2,3,5,6-Tetrafluorobenzyl Alcohol
  参考文献:World Intellectual Property Organization]
  
  327-54-8 = 92339-07-6
  反应条件:1.1 Reagents: Sulfuric Acid,Chlorosulfonic Acid Catalysts: Zinc Chloride; 3 H,45 °C; 2 H,58 °C1.2 Reagents: Sodium Carbonate Solvents: Ethanol,Water; 10 H,Reflux
  标题:Process For Preparation Of 2,3,5,6-Tetrafluoro-1,4-Benzenedimethanol
  参考文献:China]
  
  89992-50-7 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Nitrite Solvents: Water; 30 Min,Rt; Rt -> 0 °C1.2 Reagents: Acetic Acid; 1 H,40 °C1.3 Reagents: Sodium Bicarbonate Solvents: Water; 1 H,40 °C
  标题:Method For The Preparation Of Benzene-Dimethanol
  参考文献:Japan]
  
  89992-50-7 = 92339-07-6
  反应条件:1.1 Reagents: Sodium Nitrite Solvents: Water1.2 Reagents: Acetic Acid1.3 Reagents: Sodium Bicarbonate
  标题:Production Method For Benzenedimethanol Compound
  参考文献:World Intellectual Property Organization]
  
  727-55-9 = 92339-07-6
  反应条件:1.1 Reagents: Potassium Borohydride Solvents: 1,2-Dimethoxyethane; 20 - 25 °C; 25 °C -> Reflux; 2 H,Reflux; Cooled1.2 Reagents: Sulfuric Acid Solvents: Water; Ph 1 - 2,Cooled
  标题:Synthesis Of Tetramethylfluthrin
  作者:He,Shu-Ze
  参考文献:Xiandai Nongyao 日期:2014 卷标:13(6) 页码:22-24]
  
  950-71-0 = 92339-07-6
  反应条件:1.1 Catalysts: 4-(Dimethylamino)Pyridine Solvents: Acetonitrile; Rt -> 80 °C1.2 Reagents: Di-Tert-Butyl Dicarbonate; 2 H,80 °C; 2 H,80 °C1.3 Reagents: Sodium Borohydride Solvents: Tetrahydrofuran; Rt -> 50 °C; 2 H,50 °C1.4 Reagents: Methanol; 1 H,50 °C; 1 H,50 °C
  标题:Method For Producing Halogen-Substituted Benzenedimethanol
  参考文献:World Intellectual Property Organization

海关参考信息

• 2902300000-甲苯
  2905110000-甲醇
  2906210000-苄醇
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

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