专利号:WO-2023105497-A1 优先权日:2021-12-10 标题:Synthesis of glp-1 analogues 发明人:GODHA ATUL KASTURCHAND; NARAYANASWAMY SATHYA VANGANUR; BHAGYARAJ ARETI VENKATA; BAVADEKAR ASLAM JAHANGIR; LAKSHMANAPPA RUDRESH; NAGOOR SHEIKSYEDALI; MURUGAN RANJITHKUMAR; GADAKH AMOL VASANTRAO; SAMBASIVAM GANESH 权利人:ANTHEM BIOSCIENCES PVT LTD 摘要:The present invention provides a method of preparation of GLP-1 peptides by using different peptide fragments having amino acid sequences SEQ ID NO:1 (Fragment IG), SEQ ID NO:2 (Fragment SG), Fragment BG, SEQ ID NO:3, and SEQ ID NO:4 5 and combinations thereof. The method of preparation is environmentally benign, simple, straightforward, and efficient and provides the end product in high yield and purity. The purification method of the peptides is also described.
专利号:WO-2024169886-A1 优先权日:2023-02-16 标 题 :Psma targeted radioactive drug for integrated diagnosis and treatment, and synthesis and use thereof 发明人:YAN CHENGLONG; YU SHANYOU; FANG PENG; ENG WAI-SI; YANG SI 权利人:NORROY BIOSCIENCE CO LTD 摘要:Provided are a PSMA targeted radioactive drug for integrated diagnosis and treatment, and the synthesis and use thereof. Specifically, the present invention relates to a compound or a pharmaceutically acceptable salt, ester or solvate thereof. The structure of the compound is as represented by formula (I). The compound can be used for diagnosing and/or treating one or more tumors, cancers or cells expressing PSMA.
专利号:US-11149065-B2 优先权日:2017-04-07 标 题:One-bead-two-compound macrocyclic library and methods of preparation and use 发明人:CAI JIANFENG; SHI YAN 权利人:UNIV SOUTH FLORIDA 摘要:A one-bead-two-compound combinatorial synthesis technique provides libraries of macrocyclic peptidomimetic compounds and compositions with use as ligands for the Ephrin type-A receptor 2 (EphA2). The one-bead-two-compound technique and libraries of macrocyclic compounds are useful as research tools in drug discovery and/or to treat or prevent a range of diseases or disorders.
专利号:CN-117683093-A 优先权日:2023-12-29 标 题:A method for solid-phase synthesis of ganirelix using fragmentation method
专利号:CN-110291099-B 优先权日:2016-12-10 标 题 :Synthesis of Liraglutide
专利号:CN-113444164-B 优先权日:2021-06-29 标题 :A kind of method for solid-phase synthesis of semaglutide