CAS: 38083-17-9; Climbazole

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CAS号55362-18-0 1-(4-Chlorophen...

咪唑,氯代醚酮置于n,N-二甲基苯甲酰胺体系中,用 甲苯 用作溶剂,化学反应 4.0H,以91%的收率获得氯咪巴唑
参考文献:新的脑膜炎奈瑟氏菌血清组y寡聚体及其合成方法
标题:新的脑膜炎奈瑟氏菌血清组y寡聚体及其合成方法
摘要:本发明涉及脑膜炎奈瑟氏菌血清组y荚膜多糖重复单元的新的寡聚体(Men‑y寡聚体)及用于合成新的men‑y寡聚体的方法.特别是,本发明涉及men‑y荚膜多糖重复单元的四聚体的化学合成,其能够用作开发针对脑膜炎球菌血清组y细菌感染的半合成和合成的缀合疫苗的候选物.

专利信息

专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人：BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:WO-2008028772-A1
优先权日:2006-09-06
标 题:Bioquinones for stimulating keratin synthesis
发明人：GIESEN MELANIE; SCHULZE ZUR WIESCHE ERIK; POPPE ELISABETH; WELSS THOMAS
权利人:HENKEL KGAA; GIESEN MELANIE; SCHULZE ZUR WIESCHE ERIK; POPPE ELISABETH; WELSS THOMAS
摘要:The present invention relates to the cosmetic use of one or more bioquinones for combating age-related changes in the hair follicles, for the promotion of keratin synthesis in the hair, and for positively influencing the structure of the hair. The invention further relates to a cosmetic method for combating age-related changes in the hair follicle, and to a method for stimulating keratin synthesis in hair.

专利号:US-7825268-B2
优先权日:2003-12-23
标 题:Alkoxylactones, alkoxylactams and alkoxythiolactams for controlling processes based on microbial interaction
发明人：STUMPE STEFAN; BREVES ROLAND; HUCHEL URSULA; JANSSEN FRANK; HAETZELT ANDRE
权利人:HENKEL AG & CO KGAA
摘要:Compounds of the Formula I, n nwherein A 1 is O or NH; A 2 is O or S; each of R 1 and R 2 is independently hydrogen, a methyl or C 2 -C 8 -saturated or mono- or doubly unsaturated, branched or linear hydrocarbon group; and R 3 is a C 1 -C 18 -saturated or mono- or doubly unsaturated, branched or linear hydrocarbon group wherein, each of R 1 , R 2 and R 3 comprises a heteroatom selected from the group consisting of O and S in the chain and/or is mono- or multiply-substituted by a substituent selected from the group consisting of halogen, hydroxy, C 1 -C 6 -alkyl, trifluoromethyl, C 1 -C 6 -alkoxy, C 6 -C 10 -aryl, and C 1 -C 6 -alkyl-C 6 -C 10 -aryl are useful for controlling the interaction process between microorganisms such as in the development and/or maturation of biofilms; multicellular swarm behavior; the concerted development of antibiotic resistances; the concerted synthesis of antibiotics; the concerted synthesis of pigments; the concerted production of extracellular enzymes; or the concerted production of virulence factors.

专利号:US-2009232915-A1
优先权日:2008-03-14
标 题 :Mixtures with a collagen synthesis boosting action
发明人：SCHMAUS GERHARD; FRANKE HELGE; LANGE SABINE
权利人:SYMRISE GMBH & CO KG
摘要:The invention relates to synergistically active, ternary mixtures which boost collagen synthesis and to the uses thereof, in particular for slowing down skin ageing and for wound healing of damaged skin. The invention furthermore relates to the use of the ternary mixtures according to the invention for treating the oral cavity and pharynx, and in particular therein for preventing and slowing down periodontitis, for building up periodontal connective tissue and for preventing and treating infections in the oral cavity and for wound healing in the oral cavity.

专利号:US-11944609-B1
优先权日:2023-06-16
标题:Antifungal ionic liquid and Amphotericin B combination
发明人：RATHER SAMI-ULLAH; WANI MOHMMAD YOUNUS; BAMUFLEH HISHAM S; ALHUMADE HESHAM; SAEED USMAN; TAIMOOR AQEEL AHMAD; ALALAYAH WALID M; RATHER IRFAN AHMAD
权利人:KING ABDULAZIZ UNIVERISTY; UNIV KING ABDULAZIZ
摘要:Provided herein are ionic liquids that can be used as antifungal agents alone or in combination with Amphotericin B. Also disclosed are methods of synthesis of the ionic liquids and inhibiting fungal growth and methods of treating fungal infections using the disclosed compounds. The disclosure provides antifungal agents that potentiate the antifungal activity of Amphotericin B, a commonly used antifungal drug that could be used alone or in combination. This combination will help control and combat the infections caused by drug resistant Candida. auris in immunocompromised patients.

专利号:WO-2024193888-A1
优先权日:2023-03-22
标题:Catechol derivatives for treatment of signs of hair aging and/or scalp aging
发明人：WELSS THOMAS; KROPF CHRISTIAN; GRUEDL SABINE; HEINEN GUDRUN
权利人:HENKEL AG & CO KGAA
摘要:The invention relates to the cosmetic use of specific catechol derivatives for combatting age-related changes in hair follicles, for promoting keratin synthesis in hair and for positively influencing hair structure. The invention further relates to a cosmetic product containing specific amounts of the catechol derivative in a suitable carrier and to a cosmetic method for stimulating hair growth and/or for eliminating, reducing, alleviating or preventing hair loss and/or for strengthening hair structure.