CAS: 41804-89-1; Potassium Trifluoromethanesulfinate

该化合物是一种白晶状固体,广泛用作有机合成的多用途试剂,其主要优势在于它能够作为三氟甲基化剂,能够在温和条件下将CF3组引入各种基体,这种化合物表现出极地溶剂的高度稳定性和溶性,并且与一系列反应条件相容,包括光redox催化,特别受到重视,因为它在制造氟化药品,农用化学品和材料方面的作用,而CF3组在其中加强了代谢稳定性和亲脂性,其高纯度和一贯性使它成为合成应用的可靠选择.

结构式图片

相似化合物

39971-65-8 2926-29-6 2926-27-4

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

  • 合成目标产物 Potassium Trifluoromethanesulfonate 主要起始原料 Trifluoromethanesulfonyl Fluoride
  • (文献来源)合成步骤主要原料 Trifluoromethanesulfonyl Fluoride

专利信息


专利号:US-5859288-A
优先权日:1995-03-24
标 题:Reagent and process for the synthesis of oxysulphide-containing fluorine-containing organic derivatives
发明人:FORAT GERARD; MAS JEAN-MANUEL; SAINT-JALMES LAURENT
权利人:RHONE POULENC CHIMIE
摘要:The invention relates to a reagent which is useful for the synthesis of oxysulphide-containing fluorine-containing organic derivatives by reacting with an oxide of sulphur, especially sulphur dioxide, characterized in that it comprises: a) a fluorocarboxylic acid of formula Ew-CF2-COOH where Ew is an electron-withdrawing group or atom which is at least partially salified by an organic or inorganic cation, and b) an aprotic polar solvent; and in that the content of releasable protons carried by its various components, including their impurities, is at most equal to half the initial molar concentration of the said fluorocarboxylic acid. This reagent can be used by heating in order to form fluorine-containing sulphinic or sulphonic acids.

专利号:US-6464895-B2
优先权日:1995-03-24
标 题 :Reagent and process which are useful for grafting a substituted difluoromethyl group onto a compound containing at least one electrophilic function
发明人:FORAT GERARD; MAS JEAN-MANUEL; SAINT-JALMES LAURENT
权利人:RHODIA CHIMIE SA
摘要:The invention relates to a nucleophilic reagent which is useful for grafting a substituted difluoromethyl group onto a compound containing at least one electrophilic function, or for the synthesis of oxysulphide-containing and fluorine-containing organic derivatives, wherein said reagent comprises:a) a fluorocarboxylic acid of formula Ew-CF2-COOH where Ew represents an electron-withdrawing atom or group, at least partially salified with an organic or inorganic cation, andb) a polar aprotic solvent;and in that the content of releasable protons carried by its various components, including their impurities, is at most equal to half the initial molar concentration of the said fluorocarboxylic acid.A synthetic process uses this reagent by heating in order to graft a substituted difluoromethyl group onto various compounds.

专利号:RU-2160252-C2
优先权日:1995-03-24
标 题:Reagent for synthesis of oxysulfonated fluorine-containing organic compounds and method of preparing oxysulfonated fluorine-containing organic compounds

专利号:CN-1139103-A
优先权日:1995-02-28
标题:Process for synthesis of hydrocarbon compounds which are fluorinated on carbon of alkyl chain

专利号:DE-69636402-T2
优先权日:1995-03-24
标 题:Reagent and process for the synthesis of organic oxysulfated and fluorinated derivatives

专利号:ES-2273343-T3
优先权日:1995-03-24
标 题 :REAGENT AND PROCEDURE FOR THE SYNTHESIS OF OXISULFURED AND FLUORATED ORGANIC DERIVATIVES.
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合成参考文献


摘要:Il'chenko, A. Y., Science of Synthesis, (2005) 18, 1162.
摘要:Il'chenko, A. Y., Science of Synthesis, (2005) 18, 1170.
摘要:Il'chenko, A. Y., Science of Synthesis, (2005) 18, 1164.
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