CAS: 66170-10-3; Trisodium (R)-5-((S)-1,2-Dihydroxyethyl)-4-Oxido-2-Oxo-2,5-Dihydrofuran-3-Yl Phosphate

相似化合物

134-03-2 6381-77-7 50-81-7

专利信息

专利号:US-2012094919-A1
优先权日:2009-03-16
标题 :Use of tripeptides
发明人：GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO
权利人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO
摘要:The present invention relates to the use of tripeptide derivatives for tightening, firming and/or moisturizing skin. Furthermore, the invention relates to a method for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue and/or proteoglycans by fibroblasts and/or keratinocytes such as in particular the synthesis of Hyaluronic acid and/or of the proteoglycans Decorin and/or Lumican.

专利号:US-11116810-B2
优先权日:2012-10-26
标 题 :Methods for treatment of skin and skin appendages with a linseed extract as an active agent activating the synthesis of antimicrobial peptides
发明人：BOTTO JEAN-MARIE; DOMLOGE NOUHA; PORTOLAN FREDERIQUE
权利人:ISP INVESTMENTS INC; ISP INVESTMENTS LLC
摘要:Methods for the treatment of irritations of the skin and skin appendages caused by microbial stresses are disclosed. The methods include providing a composition comprising a linseed extract, obtained from hydrolysis of linseed proteins, as an active antimicrobial agent in a physiologically acceptable medium, and topically applying the linseed extract onto the skin in need thereof. The methods may be useful in the cosmetic and pharmaceutical field and, more particularly, in the field of dermatology. Cosmetic methods for reinforcing the chemical barrier function of healthy and/or sensitive skin and skin appendages are also disclosed that include the same or similar composition and steps.

专利号:US-2009232915-A1
优先权日:2008-03-14
标 题 :Mixtures with a collagen synthesis boosting action
发明人：SCHMAUS GERHARD; FRANKE HELGE; LANGE SABINE
权利人:SYMRISE GMBH & CO KG
摘要:The invention relates to synergistically active, ternary mixtures which boost collagen synthesis and to the uses thereof, in particular for slowing down skin ageing and for wound healing of damaged skin. The invention furthermore relates to the use of the ternary mixtures according to the invention for treating the oral cavity and pharynx, and in particular therein for preventing and slowing down periodontitis, for building up periodontal connective tissue and for preventing and treating infections in the oral cavity and for wound healing in the oral cavity.

专利号:US-2008194417-A1
优先权日:2005-03-09
标 题:Method for Measuring and Comparing the Activity of Biologically Active Compounds
发明人：BARELLA LUCA; MULLER PATRICK Y; NETSCHER THOMAS; STOECKLIN ELISABETH
权利人:BARELLA LUCA; MULLER PATRICK Y; NETSCHER THOMAS; STOECKLIN ELISABETH
摘要:Biologically active compounds (e.g. from the groups of pharmaceutical drugs, cofactors, hormones, vitamins or phytochemicals) often consist of two or more stereoisomers (enantiomers or diastereoisomers) which may differ in their pharmacodynamic/kinetic, toxicological and biological properties. These differences are so far difficult to detect. A well known example for a biologically active compound and its counterpart is vitamin E which is predominantly administered as two different ‘forms’, one derived from natural sources (mainly soybeans), and one from production by chemical total-synthesis. While vitamin E from natural sources occurs as a single stereoisomer (RRR-α-tocopherol), so-called synthetic vitamin E (all-rac-α-tocopherol) is an equimolar mixture of eight stereoisomers. The present invention is directed to a method for calculating the biological activity of a biologically active compound (e.g. RRR-α-tocopherol) and a counterpart thereof (e.g. all-rac-α-tocopherol), comprising the steps of: culturing a plurality of cells in a culture medium and treating the cells with different concentrations of either said compound or said counterpart thereof; or treating a plurality of animals or plants with different concentrations of either said compound or said counterpart; preparing samples from the treated cells or animals or plants containing a pool of target nucleic acids comprising RNA transcripts; detecting the expression of genes in said cells by measuring the amount of transcripts of said genes to obtain a target expression pattern by hybridizing said pool of target nucleic acids to an array of nucleic acid probes immobilized on a surface, wherein said array comprising at least 10 different nucleic acids, some of which comprise control probes, and wherein each different nucleic acid is localized in a known location of said surface; quantifying the hybridization of said nucleic acids to said array by comparing binding of matched and control probes; calculating the biological activity of the compound and its counterpart therefrom.

专利号:US-2008081082-A1
优先权日:2000-11-21
标题:Topical Skin Compositions, Their Preparation, and Their Use
发明人：ZIMMERMAN AMY C; DEPPA DEBRA J; O'TOOLE DEBORAH A; MAYNE JAMES R
权利人:ACCESS BUSINES GROUP INTERNAT
摘要:Topical skin compositions include a complex containing components to provide a defense against the various pathway mechanisms of free radicals, reactive oxygen species, reactive nitrogen species, and other oxidizing species on the human body including the skin. The compositions may be administered by topically applying them in an amount to inhibit those mechanisms. The compositions and methods are directed to the prevention of the adverse or detrimental effects of free radicals, reactive oxygen species, reactive nitrogen species, and other oxidizing species on the human body including the skin. Thus, the compositions according to the invention improve barrier function, inhibit elastase and collagenase, and/or promote synthesis of collagen and elastin.

专利号:US-2008124409-A1
优先权日:2000-11-21
标题 :Topical Skin Compositions, Their Preparation, and Their Use
发明人：ZIMMERMAN AMY C; DEPPA DEBRA J; O'TOOLE DEBORAH A; MAYNE JAMES R
权利人:ACCESS BUSINESS GROUP INT LLC
摘要:Topical skin compositions include a complex containing components to provide a defense against the various pathway mechanisms of free radicals, reactive oxygen species, reactive nitrogen species, and other oxidizing species on the human body including the skin. The compositions may be administered by topically applying them in an amount to inhibit those mechanisms. The compositions and methods are directed to the prevention of the adverse or detrimental effects of free radicals, reactive oxygen species, reactive nitrogen species, and other oxidizing species on the human body including the skin. Thus, the compositions according to the invention improve barrier function, inhibit elastase and collagenase, and/or promote synthesis of collagen and elastin.