CAS: 72218-68-9; 2'-Bromo-2'-Deoxyuridine-82Br

相似化合物

4753-02-0 784-71-4 69123-94-0

专利信息

专利号:US-5200514-A
优先权日:1990-01-19
标 题 :Synthesis of 2'-deoxypyrimidine nucleosides
发明人：CHU CHUNG K
权利人:UNIV GEORGIA RES FOUND
摘要:A method for the preparation of 2'-deoxynucleosides and 2',3'-dideoxy-2',3'-didehydronucleosides that includes the step of reacting a nucleoside having hydroxyl groups in the 2' and 3' positions with a mixture of acyl bromide or chloride and HX, wherein X is Br or Cl, at moderate temperature, to give a haloacyl nucleoside derivative that can be deprotected and reduced to form the desired compound.

专利号:US-3873516-A
优先权日:1973-05-29
标 题:Process for the preparation of 1-{8 {62 -D-2-substituted-2-deoxyribofuranosyl{9 -pyrimidines
发明人：KOTICK MICHAEL PAUL; POLAZZI JOSEPH ODO
权利人:MILES LAB
摘要:The synthesis of 1-( Beta -D-2''-halogeno-2''-deoxyribofuranosyl)- and 1-( Beta -D-2''-mercapto-2''-deoxyribofuranosyl)pyrimidine derivatives from corresponding 2,2''-anhydro-1-( Beta D-arabinofuranosyl)-pyrimidine precursors is improved by utilization of N,N-dimethylformamide as the reaction solvent.

专利号:EP-0513067-A1
优先权日:1990-01-19
标题 :A pratical synthesis of 2'-deoxynucleosides and 2',3'-dideoxy-2',3'-didehydronucleosides

专利号:WO-9110670-A1
优先权日:1990-01-19
标题:A pratical synthesis of 2'-deoxynucleosides and 2',3'-dideoxy-2',3'-didehydronucleosides

专利号:CA-2074184-A1
优先权日:1990-01-19
标 题:Practical synthesis of 2'-deoxynucleosides and 2',3'-dideoxy-2'3'-didehydronucleosides

专利号:US-2005042632-A1
优先权日:2002-02-13
标题:Antibodies having specificity for nucleic acids
发明人：RADKA SUSAN F
权利人:SIRNA THERAPEUTICS INC
摘要:The present invention relates to antibodies, antibody conjugates, and compositions thereof, methods of antibody synthesis, and applications of antibodies useful for detecting the presence of nucleic acid molecules, including short interfering RNA (siRNA) molecules, in vivo, such as in a clinical setting. The antibodies of the invention are also useful as screening agents which allow the selection of candidate therapeutic molecules for optimum bioavailability and/or activity, and as delivery agents for cell and tissue specific delivery of nucleic acid molecules.