CAS: 97-67-6; (S)-2-Hydroxysuccinic Acid

• 英文名称(S)-2-Hydroxysuccinic Acid
• 中文名称L-苹果酸,食品级
• IUPAC名称(S)-2-hydroxysuccinic acid
• 其它别名Apple Acid; L-2-Hydroxybutanedioic Acid; Malic-Acid; L-Maleic Acid; L-Malic Acid [who-Dd]; (S)-Hydroxybutanedioic Acid; (S)-Hydroxy-Butanedioic Acid; 4Elc; L-(-)-Malic Acid, Bioxtr
• CAS编号97-67-6
• MFCD编号:MFCD00064213
• EINECS号:202-601-5
• 分子式:C4H6O5
• 分子量:134.09
• 产品CID: 2022606
• 产品分类有机原料→官能团→羧酸

• 相似结构搜索
• 产品信息参考;;;;
• InChIKey: BJEPYKJPYRNKOW-REOHCLBHSA-N
• InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1…
• 计算化学: 氢键受体数3.0氢键供体数3.0可旋转键数3.0

相似化合物

物理性质

• 熔点101-103°C
• 沸点167.16 °C at 760 mmHg
• 闪点220 °C
• 密度600kg/m3
• PH:-2 º (c=8.5, H2O)
• pKa:(1) 3.46, (2) 5.10(at 25°C)
• PSA:94.83
• LogP:-1.0934
• 旋光度-2º(C=8.5,H2O)
• 折射率-6.5 ° (C=10, Acetone)
• 蒸汽压0Pa at 25°C
• 溶解性水: 0.5 M At 20 °c, Clear, Colorless
• 外观形态白色粉末
• 储存条件存储低于 +30°C.
• 产品应用用于制造酯类;用于络合剂和调味剂.按我国GB2760-90规定,可用于各类食品.作为酸味剂,可代替柠檬酸使用(约80),特别适用于果冻及水果为基料的食品.该品有保持天然果品色泽的作用,亦可作为果胶的萃取助剂,促进酵母生长用剂,配制无盐酱油,食醋,提高腌菜用味及人造奶油,蛋黄酱等的乳化稳定剂.广泛用于各种防腐,调味等复配添加剂.
• 性质描述无色结晶.熔点100°C,相对密度1.595(20/4°C),沸点约140°C(分解).易溶于水.1g该品能溶于1.4ml醇,1.7ml醚,0.7ml甲醇,2.3ml丙醇,几乎不溶于苯.具有适宜的酸味.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别严重眼刺激 类别2
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  急性毒性 类别4(经口)
  严重眼损伤 类别1
• 警示词Warning(警告)
• 危险描述H319 |造成严重眼刺激.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H302 |吞咽有害.
  H336 |可能引起嗜睡或头晕.
  H318 |造成严重眼损伤.
• 防范说明P264-P280-P302+P352-P305+P351+P338-P362+P364
• UN编号NONH for all modes of transport
• 危险品标志Xi
• 安全声明26-36-37/39
• 危险类别码36/37/38
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 L-Malic Acid 主要起始原料 Largazole
• 6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:Kinetics And Decay Of Fumarase Activity Of Immobilized Brevibacterium Ammoniagenes Cells For Continuous Production Of L-Malic Acid
  作者:Yamamoto,Kozo; Tosa,Tetsuya; Yamashita,Kiyokazu; Chibata,Ichiro
  参考文献:Biotechnology And Bioengineering 日期:1977 卷标:19(8) 页码:1101-14]
  
  63441-17-8 = 97-67-6
  反应条件:1.1 Reagents: Fumaric Acid,Sodium Fumarate; 2 H,Ph 3.0,70 °C; 70 °C -> 20 °C1.2 Reagents: Sodium Hydroxide Solvents: Water; Ph 7 - 8
  标题:Process For Preparation Of L-Malic Acid
  参考文献:China]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:Enzymic Production Of L-Malate From Maleate By Alcaligenes Sp
  作者:Kimura,Takuhei; Kawabata,Yasuro; Sato,Eiji
  参考文献:Agricultural And Biological Chemistry 日期:1986 卷标:50(1) 页码:89-94]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:Biotechnological Production Of L-Malic Acid
  参考文献:Federal Republic Of Germany]
  
  97-67-6 = 97-67-6
  反应条件:1.1 Reagents: Sodium Hydroxide,Chromium Chloride (Crcl3) Solvents: Water; 8 Min,Ph 5,Rt -> 60 °C; 4 H,Reflux
  标题:Anti-Hyperglycemic Activity Of Chromium(Iii) Malate Complex In Alloxan-Induced Diabetic Rats
  作者:Wu,Xiang-Yang; Li,Fang; Xu,Wei-Dong; Zhao,Jiang-Li; Zhao,Ting; Et Al
  参考文献:Biological Trace Element Research 日期:2011 卷标:143(2) 页码:1031-1043]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:Production Of L-Malic Acid By Immobilized Bacterial Cells Of The Genus Brevibacterium
  作者:Cerny,Jaroslav; Skoda,Jan
  参考文献:Collection Of Czechoslovak Chemical Communications 日期:1986 卷标:51(6) 页码:1361-72]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:Conversion Of Fumaric Acid Fermentation To L-Malic Acid Fermentation By The Association Of Rhizopus Arrhizus And Proteus Vulgaris
  作者:Takao,Shoichi; Hotta,Kunimoto
  参考文献:Hakko Kogaku Zasshi 日期:1976 卷标:54(4) 页码:197-204]
  
  7704-73-6 = 97-67-6
  反应条件:1.1 Solvents: Water; 42 H,Ph 7.5,37 °C
  标题:Preparation Method For L-Malic Acid
  参考文献:Slovakia]
  
  110-17-8 = 97-67-6
  反应条件:1.1 Reagents: Calcium Carbonate Solvents: Water; 3 H,Ph 7.5 - 8,85 °C1.2 35 H,30 °C1.3 Reagents: Sodium Carbonate Solvents: Water; 2 H,90 °C
  标题:Preparation Method Of L-Malic Acid
  参考文献:China]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:L-Malic Acid From Fumaric Acid
  参考文献:Federal Republic Of Germany]
  
  = 97-67-6
  反应条件:1.1 Reagents: 4-Acetamido-Tempo Catalysts: Eosin Solvents: Water; 28 H,Ph 8.5,25 °C1.2 Reagents: Hydrochloric Acid Catalysts: Fumarate Hydratase,Maleate Hydratase Solvents: Water; 20 Min,Ph 8.5,25 °C
  标题:Combining Electro-,Photo-,And Biocatalysis For One-Pot Selective Conversion Of Furfural Into Value-Added C4 Chemicals
  作者:Lu,Guang-Hui; Zong,Min-Hua; Li,Ning
  参考文献:Acs Catalysis 日期:2023 卷标:13(2) 页码:1371-1380]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:Production Of L-Malic Acid By The Cell Reusing Process
  作者:Yukawa,Hideaki; Yamagata,Hisashi; Terasawa,Masato
  参考文献:Process Biochemistry (Rickmansworth 日期:1986 卷标:21(5) 页码:164-6]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:Conversion Of Fumaric Acid Fermentation To L-Malic Acid Fermentation With A Combination Of Rhizopus And Yeast. I. Conversion Of Fumarate To L-Malate By Yeast
  作者:Sasaki,Yuji; Takao,Shoichi
  参考文献:Nippon Nogei Kagaku Kaishi 日期:1965 卷标:39(11) 页码:436-41]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:Immobilizing A Biological Material
  参考文献:European Patent Organization]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:Preparation Of L-Malate From Fumarate By Enzymic Transcrystallization
  作者:Kitahara,Kakuo; Fukui,Sakuzo; Misawa,Masanaru
  参考文献:Journal Of General And Applied Microbiology 日期:1960 卷标:6 页码:108-16]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:L-Malic Acid Fermentation By A Mixed Culture Of Rhizopus Arrhizus And Paecilomyces Varioti
  作者:Takao,Shoichi; Yokota,Atsushi; Tanida,Masatoshi
  参考文献:Journal Of Fermentation Technology 日期:1983 卷标:61(6) 页码:643-5]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:L-Malic Acid Formation By Immobilized Saccharomyces Cerevisiae Amplified For Fumarase
  作者:Neufeld,R. J.; Peleg,Y.; Rokem,J. S.; Pines,O.; Goldberg,I.
  参考文献:Enzyme And Microbial Technology 日期:1991 卷标:13(12) 页码:991-6]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:L-Malic Acid Fermentation By Mixed Culture Of Rhizopus Arrhizus And Proteus Vulgaris
  作者:Takao,Shoichi; Hotta,Kunimoto
  参考文献:Agricultural And Biological Chemistry 日期:1977 卷标:41(6) 页码:945-50]
  
  50-99-7 = 97-67-6
  反应条件:1.1 Reagents: (+)-Xylose,Calcium Carbonate,Sulfuric Acid Magnesium Salt (1:1),Ferrous Sulfate,Dipotassium Phosphate,Monopotassium Phosphate,Ammonium Sulfate,Nickel Sulfate Hexahydrate Solvents: Water; 30 Min,Ph 6.2,30 °C
  标题:Production Of Malic Acid
  参考文献:China]
  
  6915-18-0 = 97-67-6 [标题:Reaction Conditions
  标题:Bioconversion Of Fumarate To 1-Malate Using Fumarase-Containing Microorganisms
  参考文献:United States]
  
  74-79-3 + 97-67-6 = 97-67-6 + 74-79-3
  反应条件:1.1 Rt; 10 Min,Rt; 55 °C; 55 °C -> 23 °C
  标题:Process For Preparation Of L-Arginine Malate
  参考文献:China

海关参考信息

• 2905122000-异丙醇
  2905310000-1,2-乙二醇
  2905320000-1,2-丙二醇
  2905399001-1,3-丙二醇
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管