Methyloxirane置于1-(2-Hydroxy-3,5-Dimethylphenyl)-N,N,N-Trimethylmethanaminium Iodide体系中,化学反应生成碳酸丙烯酯 参考文献:Modular Synthesis Of Spirocyclic Carbonates: Unravelling The Synergistic Interplay Of Electronic And Electrostatic Sites On Phenolic Catalyst 标题:Modular Synthesis Of Spirocyclic Carbonates: Unravelling The Synergistic Interplay Of Electronic And Electrostatic Sites On Phenolic Catalyst 摘要:螺环碳酸盐:研究证明了一种简单高效的有机催化方法,可将二氧化碳与螺环氧吲哚进行化学固定.该催化方案可为新应用提供更多可能性. Doi:10.1039/d3Gc03989G
专利信息
专利号:US-2023287032-A1 优先权日:2020-08-14 标 题:Synthesis of fluorinated nucleotides 发明人:CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO 权利人:CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO; MERCK SHARP & DOHME LLC 摘要:The present invention relates to efficient processes useful in the preparation of fluorinated nucleosides, such as (O—{[(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl}O,O-dihydrogen phosphorothioate, also known as 2′-(S)-fluoro-thio-adenosine monophosphate or 2′-F-thio-AMP. Such fluorinated nucleosides may be useful as a biologically active compound and or as an intermediate for the synthesis of more complex biologically active compounds. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.
专利号:US-9969823-B1 优先权日:2011-09-01 标题 :Synthesis and polymerization of vinyl triazolium ionic liquids 发明人:LUEBKE DAVID; NULWALA HUNAID; MATYJASZEWSKI KRZYSZTOF; ADZIMA BRIAN 权利人:US ENERGY; THE US DEPARTMENT OF ENERGY 摘要:Herein, we describe polymerized ionic liquids, demonstrate the synthesis of polymerized ionic liquids, and demonstrate the polymerization of triazolium monomers. One embodiment shows the polymeriazation of the triazolium monomers with bis(trifluoromethanesulfonyl)imide anions. In another embodiment we show the feasibility of copolymerizing with commodity monomers such as styrene using free radical polymerization techniques.
专利号:US-6399536-B2 优先权日:2000-02-11 标 题 :High performance catalyst systems for the synthesis of alkylenecarbonates 发明人:KIM HOON SIK; LEE BYUNG GWON; LEE SANG DEUK; KWON YOUNG SOO; LEE HYUN JOO 权利人:KOREA INST SCI & TECH 摘要:A catalyst of the formula (1) for the synthesis of alkylene carbonate by reacting alkylene oxide and carbon dioxide n n n L m MX n   (1) n n n wherein L is selected from a group of pyridines; n M is a metal atom selected from Zn, Fe, Mn, Pb and In; n X is a halogen atom selected from Cl, Br and I; n m is 1 or 2, and n n is 2 or 3.
专利号:US-9475780-B2 优先权日:2011-07-20 标 题 :Process for the synthesis of cyclic alkylene ureas 发明人:GUPTA RAM; KOBYLANSKA IRINA; TREASURER URVEE; FLOOD LAWRENCE 权利人:GUPTA RAM; KOBYLANSKA IRINA; TREASURER URVEE; FLOOD LAWRENCE; ALLNEX IP S AR L 摘要:The invention relates to a process for the synthesis of cyclic alkylene ureas comprising reacting in the presence of a basic catalyst, a difunctional amine A having two primary amino groups, and an aliphatic organic carbonate component C selected from the group consisting of dialkyl carbonates CD and of alkylene carbonates CA, wherein the ratio of the amount of substance Ji(—NH2) of primary amino groups —NH2 in the difunctional amine A to the sum M(C) of the amount of substance n(CD) of carbonate groups of a dialkyl carbonate CD and the amount of substance n(CA) of carbonate groups in an alkylene carbonate CA, is at least more than 2, and to the product obtained by this process.
专利号:US-9440928-B2 优先权日:2011-07-20 标题 :Process for the synthesis of N-substituted cyclic alkylene ureas 发明人:GUPTA RAM; KOBYLANSKA IRINA; TREASURER URVEE; FLOOD LAWRENCE 权利人:GUPTA RAM; KOBYLANSKA IRINA; TREASURER URVEE; FLOOD LAWRENCE; ALLNEX IP S AR L 摘要:The invention relates to a process for the synthesis of N-substituted cyclic alkylene ureas by reacting a multifunctional aliphatic amine A having at least two amino groups which may be primary or secondary, at least one of which is a primary amino group, —NH 2 , and at least one of which is a secondary amino group, >NH, the other hydrogen group whereof having been substituted by a hydrocarbyl group which in turn may be substituted by a hydroxyl group, or an amino group, or a carboxyl group, or a ketone carbonyl group, or a hydrazide or hydrazone group, or a mercaptan group, and at least one further functional group selected from the group consisting of primary or secondary amino groups and hydroxyl groups, and an aliphatic organic carbonate component C selected from the group consisting of dialkyl carbonates CD and of alkylene carbonates CA.
专利号:US-8158817-B2 优先权日:2003-12-24 标 题 :Synthesis of acylureas and composition comprising acylureas 发明人:BERNARD JEAN-MARIE; REVELANT DENIS; AMOUYAL CEDRIC 权利人:BERNARD JEAN-MARIE; REVELANT DENIS; AMOUYAL CEDRIC; PERSTORP FRANCE 摘要:The invention relates to a process for the synthesis of a polyisocyanate composition comprising acylureas. According to the invention, a starting composition comprising a compound having at least two isocyanate functional groups is subjected to a reaction with at least two acid functional groups, with at least one of the acid functional groups having a pKa value of less than or equal to 3, and at least one of the acid functional groups having a pKa value of more than 3 and less than or equal to 6, at a temperature at least equal to 50 ° C., wherein the acid functional group having a pKa value of less than or equal to 3 and the acid functional group having a pKa value of more than 3 and less than or equal to 6 are present on two different acids or on the same acid.
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合成参考文献
参考文献:10.1007/s10856-011-4387-3 摘要:Lynam D, Bednark B, Peterson C, Welker D, Gao M, Sakamoto JS. Precision microchannel scaffolds for central and peripheral nervous system repair. Journal of Materials Science: Materials in Medicine. 2011 Jul 16;22(9):2119. doi: 10.1007/s10856-011-4387-3. 参考文献:10.1039/c1pp05141e 摘要:Caprasecca S, Curutchet C, Mennucci B. Quantum mechanical study of the solvent-dependence of electronic energy transfer rates in a Bodipy closely-spaced dyad. Photochemical & Photobiological Sciences. 2011 Oct;10(10):1602–9. doi: 10.1039/c1pp05141e. 参考文献:10.1039/c1pp05123g 摘要:Guzow K, Ceszlak A, Kozarzewska M, Wiczk W. Influence of substituents on the nitrogen atom of 3-[2-(4-aminophenyl)benzoxazol-5-yl]alanine derivatives on their photophysical properties - solvatochromic studies. Photochemical & Photobiological Sciences. 2011 Oct;10(10):1610–21. doi: 10.1039/c1pp05123g.