CAS: 139102-34-4; Methyl 4-Bromo-2-Methoxybenzoate

相似化合物

43192-33-2 72135-36-5 17102-63-5

上下游产品

CAS号1666-28-0 2-羟基-4-溴苯甲酸 | CAS号74-88-4 碘甲烷 | CAS号22717-56-2 2-羟基-4-溴苯甲酸甲酯 | CAS号72135-36-5 2-甲氧基-4-溴苯甲酸 | CAS号43192-33-2 4-溴-2-甲氧基苯甲醛 | CAS号72135-36-5 2-甲氧基-4-溴苯甲酸 | CAS号603122-40-3 3-甲氧基-4-甲氧羰基苯硼酸频呢醇酯 | CAS号175153-18-1 3-甲氧基-[1,1-联苯]-4-羧酸 | CAS号17102-63-5 4-溴-2-甲氧基苯甲醇 | CAS号812667-44-0 4-bromo-2-metho... | CAS号5213-16-1 7-Chloro-2-phen...

2-羟基-4-溴苯甲酸置于硫酸,Potassium Carbonate体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 24.0H,反应生成4-溴-2-甲氧基苯甲酸甲酯
参考文献:Design Of Potent And Selective Hybrid Inhibitors Of The Mitotic Kinase Nek2: Structure-activity Relationship,Structural Biology,And Cellular Activity
标题:Design Of Potent And Selective Hybrid Inhibitors Of The Mitotic Kinase Nek2: Structure-activity Relationship,Structural Biology,And Cellular Activity
摘要:We Report Herein A Series Of Nek2 Inhibitors Based On An Aminopyridine Scaffold. These Compounds Have Been Designed By Combining Key Elements Of Two Previously Discovered Chemical Series. Structure Based Design Led To Aminopyridine (R)-21,A Potent And Selective Inhibitor Able To Modulate Nek2 Activity In Cells.
Doi:10.1021/jm201683B

专利信息

专利号:US-9920056-B2
优先权日:2015-06-16
标题:2-oxo-1,3,8-triazaspiro[4.5]decan-3-yl] carboxylic acid derivatives
发明人：BEAUCHAMP THOMAS JAMES; COATES DAVID ANDREW; MARTINEZ-GRAU MARIA ANGELES; TOLEDO MIGUEL ANGEL
权利人:LILLY CO ELI
摘要:The present invention provides compounds of Formula 1, n nwhere A is selected fromn n nand R1, R2 and R3 are defined in the specification, or a pharmaceutically acceptable salt thereof, methods of using the compounds to treat diabetes, and processes for the synthesis of the compounds.

专利号:WO-2023226658-A1
优先权日:2022-05-25
标题:Nitrogen-containing five-membered heterocyclic derivatives as checkpoint kinase 1 inhibitor and uses thereof
发明人：LIU HANLAN; MA JINGJING; HUANG YUNG-JEN; CAI ZHANG; WANG XIAOHUI; YAN ZHIYU; KHAN PASHA M; PANPATIL DAYANAND; PUJALA BRAHMAM; RUAN JUXIN
权利人:SPEROGENIX THERAPEUTICS LTD
摘要:The present disclosure relates generally to nitrogen-containing five-membered heterocyclic derivatives usefulness in treatment of conditions associated with Checkpoint kinase (CHK), particularly more specifically CHK-1 enzymes. Methods of use, compositions, and method of synthesis are also disclosed.

专利号:CN-117304067-A
优先权日:2022-06-21
标 题 :Synthesis method of non-nefardone intermediate 4-cyano-2-methoxybenzaldehyde