CAS: 53600-33-2; 2-Amino-6-Methoxybenzoic Acid

上下游产品

CAS号53967-73-0 2-甲氧基-6-硝基苯甲酸 | CAS号1591-37-3 2-氨基-6-甲氧基苯甲腈 | CAS号606-20-2 2,6-二硝基甲苯 | CAS号603-12-3 2,6-二硝基苯甲酸 | CAS号42087-82-1 2,6-二硝基苯甲酸甲酯 | CAS号77901-52-1 2-甲氧基-6-硝基苯甲酸甲酯 | CAS号38469-85-1 2-甲氧基-6-硝基苯甲腈 | CAS号136247-94-4 N-(tert-butoxyc... | CAS号60144-52-7 (3-甲氧基苯基)氨基甲酸叔丁酯 | CAS号536-90-3 间氨基苯甲醚 | CAS号3260-89-7 2-氯-6-甲氧基苯甲酸 | CAS号31786-45-5 2-溴-6-甲氧基苯甲 酸 | CAS号37795-77-0 5-甲氧基靛红酸酐 | CAS号219773-55-4 1-[[5-甲氧基-2-(2-... | CAS号66195-39-9 2-碘-6-甲氧基苯甲酸 | CAS号331662-64-7 4-羟基-5-甲氧基喹啉-3-甲腈 | CAS号331662-72-7 4-氯-5-甲氧基-3-喹啉甲腈 | CAS号177531-95-2 Benzenemethanol... | CAS号254964-60-8 他喹莫德 | CAS号151585-95-4 2-氨基-6-甲氧基苯甲醛

2,6-二硝基甲苯置于palladium On Activated Charcoal Sodium Hydroxide,Sodium Dichromate,硫酸,氢气,碳酸氢钠体系中,用 甲醇,乙醇,丙酮 作为反应溶剂,25.0 °C,101.33 Kpa 条件下,反应 61.0H,反应生成 2-氨基-6-甲氧基苯甲酸
参考文献:Warrener,Ronald N.; Russel,Richard A.; Marcuccio,Sebastian M.,Australian Journal Of Chemistry,1980,Vol. 33,# 12,P. 2777-2779
标题:Warrener,Ronald N.; Russel,Richard A.; Marcuccio,Sebastian M.,Australian Journal Of Chemistry,1980,Vol. 33,# 12,P. 2777-2779

专利信息

专利号:US-4154745-A
优先权日:1977-05-02
标题:Isobenzofuran route to anthracycloquinones
发明人：KENDE ANDREW S; TSAY YUH-GENG
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain tetracyclic quinones. In particular, there is provided a novel route to the synthesis of (±)-7-deoxydaunomycinone and analogs thereof which includes the provision of novel tetrahydronaphthoquinones and tetracyclic quinone intermediates. The compounds of the present invention are provided through a route comprising a Diels-Alder addition of certain isobenzofurans to certain novel tetrahydronaphthoquinones. The products of the synthetic route provided herein may be converted into compounds of known antibiotic and antineoplastic activity.

专利号:US-2015315143-A1
优先权日:2014-05-01
标题 :N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles

专利号:US-9527812-B2
优先权日:2014-05-01
标题 :N-heterocyclic carbene-catalyzed synthesis of 2-aryl indoles
发明人：SCHEIDT KARL A; HOVEY JR MICHAEL TODD; CHECK CHRISTOPHER
权利人:UNIV NORTHWESTERN
摘要:Transition metal-free catalytic methods for access to 2-arylindole compounds.

专利号:US-8461107-B2
优先权日:2008-04-28
标题:HCV NS3 protease inhibitors
发明人：LIVERTON NIGEL J; MCCAULEY JOHN A; BUTCHER JOHN W; GILBERT KEVIN F; MCINTYRE CHARLES J; RUDD MICHAEL T
权利人:LIVERTON NIGEL J; MCCAULEY JOHN A; BUTCHER JOHN W; GILBERT KEVIN F; MCINTYRE CHARLES J; RUDD MICHAEL T; MERCK SHARP & DOHME
摘要:The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.

专利号:US-9133224-B2
优先权日:2010-11-29
标 题:Macrocyclic kinase inhibitors
发明人：CREW ANDREW P; DONG HANQING; FERRARO CATERINA; SHERMAN DAN; SIU KAM W
权利人:CREW ANDREW P; DONG HANQING; FERRARO CATERINA; SHERMAN DAN; SIU KAM W; OSI PHARMACEUTICALS LLC
摘要:Compounds of Formula (I): wherein variables are defined herein, and pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancers for which FAK inhibition is beneficial.

专利号:US-10669274-B2
优先权日:2017-03-31
标 题 :Azaphenalene-3-one derivative, preparation method therefor, and application therof
发明人：ZHANG HAO; WANG XIAODONG; XU WEILIANG; XU WEIZHENG
权利人:SUZHOU KANGRUN PHARMACEUTICALS INC
摘要:Disclosed are an azaphenalene-3-one derivative, its preparation method and its application, in the field of pharmaceutical synthesis. The derivative has the following Formula (I), wherein R is H, 2-fluoroethylamino, 2,2,2-trifluoroethylamino, diethylamino, pyrrolidinyl, imidazolyl, piperidinyl, morphinolinyl, 4-methylaminopiperidinyl, 4-dimethylaminopiperidinyl, (1-methylpiperidin-4-yl)methylamino, (1-phenylpiperidin-4-yl)methylamino, (1-benzylpiperidin-4-yl)methylamino, or 7-fluoro-3,4-dihydroisoquinoline-2(1H)-yl. The preparation method of the azaphenalene-3-one derivative is simple, the yield is high, post-treatment is easy, and purity is high. The derivative has high inhibitory activity against PARP enzyme. It establishes a foundation for researching better anti-tumor drugs using PARP inhibitors.