CAS: 625-84-3; 2,5-Dimethyl-1H-Pyrrole

相似化合物

636-41-9 625-82-1 1192-79-6

上下游产品

CAS号628-16-0 1,5-己二炔 | CAS号625-86-5 2,5-二甲基呋喃 | CAS号110-13-4 2,5-己二酮 | CAS号59480-92-1 2,5-二甲基-3-吡咯啉(顺... | CAS号999-97-3 六甲基二硅氮烷 | CAS号143-33-9 氰化钠 | CAS号78133-60-5 N-(2,5-dimethyl... | CAS号3378-71-0 2,5-二甲基吡咯烷(顺反异构体混合物) | CAS号2199-52-2 2,5-二甲基吡咯-3-乙酯 | CAS号3430-31-7 2,6-二甲基-3-溴吡啶 | CAS号3757-53-7 5-甲基-1H-吡咯-2-甲酸 | CAS号5044-27-9 1-(4-甲氧基苯基)-2,5... | CAS号937-27-9 1H-吡咯-2,5-二羧酸 | CAS号2199-63-5 2,5-二甲基-1H-吡咯-3-甲醛 | CAS号56139-74-3 2,5-二甲基-1H-吡咯-3... | CAS号2405-06-3 3-chloro-2,6-di... | CAS号2157-57-5 N-(5-hydroxyimi... | CAS号20282-40-0 1-butyl-2,5-dim... | CAS号123-31-9 对苯二酚

2,5-二甲基呋喃置于氨体系中,用 正庚烷 作为反应溶剂,150.0 °C,2.0 Mpa 条件下,反应 3.0H,以62%的收率获得产物2,5-二甲基吡咯
参考文献:苯胺与生物衍生呋喃的多相催化缩合直接合成吡咯
标题:苯胺与生物衍生呋喃的多相催化缩合直接合成吡咯
摘要:鉴于吡咯在农业,制药,超分子和材料化学中的广泛应用,非常需要一种温和且环保的途径,以生物衍生的原料生产功能化的吡咯.本文描述了通过简单和有效的固体酸h形式的沸石y催化剂催化的等摩尔量的结构上不同的苯胺与生物基呋喃的直接缩合,温和且方便地合成吡咯.该方案可耐受多种官能团,并提供了一种通用且通用的方法,用于按比例放大合成各种n-取代的吡咯化合物.最重要的是,可以通过这种方法获得最近被证实对治愈结肠癌非常有效的生物活性吡咯衍生药物吡虫鎓.
DOI:10.1021/acscatal.6B02953

专利信息

专利号:WO-2025134143-A1
优先权日:2023-12-19
标题 :A method for the synthesis of substituted anthranilic amide compounds, intermediates and salts thereof
发明人：MALVIYA NITIN JAIKANT; SINGH VIPENDER; MAL SANJIB; YADAV SANTOSH; SHAH JIGARKUMAR HARKISHANDAS; KAVITAKE SANTOSH GIRIDHAR; BORHADE AJIT SAHEBRAO; KLAUSENER ALEXANDER G M
权利人:PI INDUSTRIES LTD
摘要:The present invention discloses a method for the synthesis of compounds of formula (I) or a salt thereof, wherein R is selected from hydrogen, halogen, cyano, C1-C12 alkyl, C1-C12 haloalkyl, C1-C12 alkoxy, C1-C12 haloalkoxy, or C3-C8 cycloalkyl; R4 is selected from hydrogen, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, C1-C12 haloalkyl, C2- C12 haloalkenyl, C2-C12 haloalkynyl, C1-C12 alkoxy, C1-C12 haloalkoxy, C3-C8 cycloalkyl, or C3-C8 cycloalkyl-C1-C10 alkyl; and n represents an integer selected from 0-4. The process further comprises the synthesis of an anthranilic diamide compound of formula (A).

专利号:US-5880295-A
优先权日:1994-02-16
标 题 :Process for the preparation of diamine intermediates useful in the synthesis of HIV protease inhibitors
发明人：KALTENBACH III ROBERT FRANK
权利人:DU PONT PHARM CO
摘要:The present invention provides a process for the preparation of compounds of formula (V) below, and analogs thereof, which are useful as intermediates for the synthesis of HIV protease inhibitors, including cyclic ureas. ##STR1##

专利号:US-6770763-B2
优先权日:2002-06-11
标题 :Asymmetric synthesis of amino-pyrrolidinones
发明人：MAGNUS NICHOLAS A; CONFALONE PASQUALE N; SAVAGE SCOTT A; YATES MATTHEW; WALTERMIRE ROBERT E; MELONI DAVID J; CAMPAGNA SILVIO
权利人:BRISTOL MYERS SQUIBB CO
摘要:A novel process for the asymmetric synthesis of an amino-pyrrolidinone of the type shown below from appropriate pyrrolidinones is described.These compounds are useful as intermediates for MMP and TACE inhibitors.

专利号:WO-2024018354-A1
优先权日:2022-07-18
标题 :A process for the synthesis of 4-alkoxy-3-hydroxypicolinic acids and intermediates thereof
发明人：MAL SANJIB; SARKAR PARANTAP; PATRA PRANAB KUMAR; KLAUSENER ALEXANDER GUENTHER MARIA
权利人:PI INDUSTRIES LTD
摘要:The present invention discloses a process for the synthesis of 4- alkoxy-3-hydroxypicolinic acids of formula (I) from 2-picolinic acid. The present invention further discloses a process for preparation of compounds of formula (iii) from compounds of formula (ii). The present invention also discloses novel intermediate compounds of formula (iii).

专利号:US-2004006137-A1
优先权日:2002-06-28
标题:Asymmetric synthesis of amino-pyrrolidinones and a crystalline, free-base amino-pyrrolidinone
发明人：WALTERMIRE ROBERT E; CAMPAGNA SILVIO; SAVAGE SCOTT A; BORDAWEKAR SHAILENDRA; MADUSKUIE THOMAS P; DESIKAN SRIDHAR; ANDERSON STEPHEN R
摘要:A novel process for the asymmetric synthesis of an amino-pyrrolidinone of the type shown below is described. n n n These compounds are useful as intermediates for MMP and TACE inhibitors. n Crystalline, free-base form of Compound J ((2R)-2-((3R)-3-amino-3-{-[(2-methyl-4-quinolinyl)methoxy]phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide): n n n which is useful as a TACE inhibitor, pharmaceutical compositions comprising the same, and methods of using the same for treating inflammatory diseases are also described.

专利号:US-8729277-B2
优先权日:2009-04-06
标 题:Processes for the synthesis of gamma nitrocarbonyl and gamma dicarbonyl compounds and their pyrrole derivatives
发明人：YANG HU; BARALT EDUARDO J
权利人:YANG HU; BARALT EDUARDO J; CHEVRON PHILLIPS CHEMICAL CO
摘要:The present invention discloses processes for producing γ-nitrocarbonyl and γ-dicarbonyl compounds, which can be precursors in the synthesis of pyrrole compounds. A process for producing pyrroles such as 2,5-dimethylpyrrole, and structurally similar pyrrole compounds, is also disclosed.