CAS: 7115-89-1; 2-(Bromomethyl)Benzoic Acid

上下游产品

CAS号118-90-1 邻甲基苯甲酸 | CAS号87-41-2 苯酞 | CAS号128-08-5 N-溴代丁二酰亚胺 | CAS号40819-28-1 2-(溴甲基)苯甲酰溴 | CAS号55741-01-0 2-[(二甲氨基)甲基]苯甲酸 | CAS号87-41-2 苯酞 | CAS号612-20-4 2-(羟基甲基)苯甲酸 | CAS号7115-91-5 2-溴甲基苯甲酸乙酯 | CAS号2417-73-4 2-溴甲基苯甲酸甲酯 | CAS号18019-57-3 1-(2-benzoylphe... | CAS号7115-90-4 2-(bromomethyl)... | CAS号74785-02-7 2-(溴甲基)苄醇 | CAS号4741-68-8 3H-2-benzofuran...

苯酞置于氢溴酸,溶剂黄146体系中,用70%的收率获得产物2-溴甲基苯甲酸
参考文献:Phthalide: A Direct Building-Block Towards P,O And P,N Hemilabile Ligands. Application In The Palladium-Catalysed Suzuki-miyaura Cross-Coupling Of Aryl Chlorides
标题:Phthalide: A Direct Building-Block Towards P,O And P,N Hemilabile Ligands. Application In The Palladium-Catalysed Suzuki-miyaura Cross-Coupling Of Aryl Chlorides
摘要:描述了从经济和易得的内酯苯邻酸内酯直接合成新型半可脱络合剂.发现这种配体的钯配合物在一般的铃木-宫浦交叉耦合反应中非常有效,包括去活化和受阻的芳香氯化物.
DOI:10.1039/c3Ob40198G

专利信息

专利号:WO-9403593-A1
优先权日:1992-08-04
标题 :Amplifier molecules for enhancement of diagnosis and therapy
发明人：KEANA JOHN F W
权利人:OREGON STATE
摘要:Disclosed are amplifier molecules: various organic compounds having branched structures terminating with amine groups to which pharmacologically active groups can be chemically attached. A number of MRI contrast-enhancing agents were synthesized, each comprising plural active groups, such as stable nitroxides and complexes of trivalent metal cations. Such syntheses were successfully performed using a number of amplifiers having different branched structures, demonstrating the general utility of the pertinent chemistry in the synthesis of amplifiers having any of a wide variety of pharmacologically active groups. Amplifiers were also synthesized having linkers terminating with chemically reactive groups such as isothiocyanates, which render the amplifier bifunctional: attachable to polymers, biomacromolecules, or other biocompatible entity possessing multiple reactive sites such as terminal amines. Via such chemistry, the amplifiers are attachable to monoclonal antibodies for concentration of pharmacologically active groups at a desired site in the body.

专利号:US-4539410-A
优先权日:1982-09-30
标题:N-Substituted-2-(1-imidazolyl)indoles
发明人：RENFROE HARRIS B
权利人:CIBA GEIGY CORP
摘要:Various 1-carboxylic acid substituted-2-(1-imidazolyl)indoles and functional derivatives thereof are highly specific thromboxane synthetase inhibitors. Synthesis of, pharmaceutical compositions thereof, methods of treatment utilizing such compounds and intermediates for their synthesis are included.

专利号:CN-108997368-A
优先权日:2018-06-29
标题 :A method for the efficient synthesis of optically active multi-substituted 2,3-dihydrobenzofuran compounds catalyzed by an asymmetric organophosphine

专利号:US-2011091957-A1
优先权日:2005-09-13
标题:Protein-polymer conjugates and synthesis thereof
发明人：LELE BHALCHANDRA SHRIPAD; RUSSELL ALAN J
权利人:LELE BHALCHANDRA SHRIPAD; RUSSELL ALAN J
摘要:A method of synthesizing a protein-polymer conjugate includes the steps: covalently attaching at least one controlled radical polymerization initiator to a protein to form a protein-initiator composition; and mixing the protein-initiator composition with at least one monomer which undergoes controlled radical polymerization in the presence of the protein-initiator composition under conditions suitable to initiate the controlled radical polymerization.

专利号:US-6090912-A
优先权日:1993-05-27
标 题:Topologically segregated, encoded solid phase libraries comprising linkers having an enzymatically susceptible bond
发明人：LEBL MICHAL; LAM KIT S; SALMON SYDNEY E; KRCHNAK VICTOR; SEPETOV NIKOLAI; KOCIS PETER
权利人:SELECTIDE CORP
摘要:The invention relates to libraries of synthetic test compound attached to separate phase synthesis supports. In particular, the invention relates to libraries of synthetic test compound attached to separate phase synthesis supports that also contain coding molecules that encode the structure of the synthetic test compound. The molecules may be polymers or multiple nonpolymeric molecules. Each of the solid phase synthesis support beads contains a single type of synthetic test compound. The synthetic test compound can have backbone structures with linkages such as amide, urea, carbamate (i.e., urethane), ester, amino, sulfide, disulfide, or carbon-carbon, such as alkane and alkene, or any combination thereof. Examples of subunits suited for the different linkage chemistries are provided. The synthetic test compound can also be molecular scaffolds, such as derivatives of monocyclic of bicyclic carbohydrates, steroids, sugars, heterocyclic structures, polyaromatic structures, or other structures capable of acting as a scaffolding. Examples of suitable molecular scaffolds are provided. The invention also relates to methods of synthesizing such libraries and the use of such libraries to identify and characterize molecules of interest from among the library of synthetic test compound.

专利号:US-5840485-A
优先权日:1993-05-27
标题 :Topologically segregated, encoded solid phase libraries
发明人：LEBL MICHAL; LAM KIT S; SALMON SYDNEY E; KRCHNAK VICTOR; SEPETOV NIKOLAI; KOCIS PETER
权利人:SELECTIDE CORP
摘要:The invention relates to libraries of synthetic test compound attached to separate phase synthesis supports that also contain coding molecules that encode the structure of the synthetic test compound. The molecules may be polymers or multiple nonpolymeric molecules. The synthetic test compound can have backbone structures with linkages such as amide, urea, carbamate (i.e., urethane), ester, amino, sulfide, disulfide, or carbon-carbon, such as alkane and alkene, or any combination thereof. Examples of subunits suited for the different linkage chemistries are provided. The synthetic test compound can also be molecular scaffolds, such as derivatives of monocyclic of bicyclic carbohydrates, steroids, sugars, heterocyclic structures, polyaromatic structures, or other structures capable of acting as a scaffolding. Examples of suitable molecular scaffolds are provided. The invention also relates to methods of synthesizing such libraries and the use of such libraries to identify and characterize molecules of interest from among the library of synthetic test compound.