50373-29-0 = 94-96-2 + 149-57-5 + 20667-04-3 + 148904-97-6 反应条件:1.1 Reagents: Lactic Acid,Nadh,L-Lactate Dehydrogenase,Putidaredoxin Reductase Catalysts: Camphor 5-Monooxygenase Solvents: Water 标题:Benign Synthesis Of 2-Ethylhexanoic Acid By Cytochrome P450Cam: Enzymatic,Crystallographic,And Theoretical Studies 作者:French,Kevin J.; Strickler,Michael D.; Rock,Dan A.; Rock,Denise A.; Bennett,Grace A.; Et Al 参考文献:Biochemistry 日期:2001 卷标:40(32) 页码:9532-9538]
18618-89-8 + 18618-91-2 = 94-96-2 反应条件:1.1 Reagents: Potassium Hydroxide Solvents: Ethanol,Water; 3 H,Reflux 标题:Isolation And Total Synthesis Of Two Novel Metabolites From The Fissurellid Mollusc Scutus Antipodes 作者:Chand,Satish; Karuso,Peter 参考文献:Tetrahedron Letters 日期:2017 卷标:58(10) 页码:1020-1023]
= 94-96-2 [标题:Reaction Conditions 标题:The Synthesis Of Glycols By Mercury-Photosensitized Alcohol Dehydrodimerization 作者:Lee,Jesse C. Jr.; Boojamra,Constantine G.; Crabtree,Robert H. 参考文献:Journal Of Organic Chemistry 日期:1993 卷标:58(15) 页码:3895-900]
= 94-96-2 [标题:Reaction Conditions 标题:Indirect Electrochemical Processes. 7. Oxidative Cleavage Of The Benzyl Ether Protective Group By Homogeneous Electron Transfer 作者:Schmidt,Werner; Steckhan,Eberhard 参考文献:Angewandte Chemie 日期:1979 卷标:91(10) 页码:850-1]
= 94-96-2 [标题:Reaction Conditions 标题:New Simple Catalyst For The Synthesis Of 1,3-Diols And Their Monoesters From Linear Aliphatic Aldehydes 作者:Pochini,A.; Ungaro,R. 参考文献:Synthesis 日期:1975 卷标:(3) 页码:164-5]
= 94-96-2 [标题:Reaction Conditions 标题:Synthesis And Application Of 2-Ethyl-1,3-Hexanediol 作者:Daniewski,Wlodzimierz; Rybczynska,Barbara 参考文献:Tno Nieuws 日期:1966 卷标:10(4) 页码:190-2
4-庚酮置于sodium Hydroxide,Lithium Aluminium Tetrahydride,乙醚体系中,化学反应生成 2-乙基-1,3-己二醇 参考文献:The Structure Of Ethylketene Dimer 标题:The Structure Of Ethylketene Dimer 摘要: DOI:10.1021/ja01149A547
专利号:US-2024368099-A1 优先权日:2022-01-18 标 题:Methods for the synthesis of di(hydroxymethyl)tetrahydrofuran and its application in polyesters and polyurethanes 发明人:SPIEGELBERG BRIAN; BRANDT ADRIAN; BECK HORST; KUX ALEXANDER; TIN SERGEY; DE VRIES JOHANNES GERARDUS 权利人:HENKEL AG & CO KGAA 摘要:The present invention relates to the synthesis of di(hydroxymethyl)tetrahydrofuran (DHMTHF) and the preparation of trans-enriched mixtures of DHMTHF. The invention further refers to polyester polyols which are obtained by reaction of cis/trans DHMTHF mixtures with a dicarboxylic acid. The invention further relates to polyurethanes and compositions containing a polyester polyol comprising DHMTHF, in particular to such polyurethane-containing (adhesive) compositions.
专利号:US-11780952-B2 优先权日:2016-08-08 标题:Process for the synthesis of silylated polyurethanes and silylated polyurethane composition 发明人:LAFERTE OLIVIER 权利人:BOSTIK SA 摘要:The present invention provides a process for the synthesis of silylated polyurethanes, comprising three sequential steps, a step (i) of preparing NCO-terminated polyurethane, a step (ii) of partial grafting of the NCO functions with silane functions and a step (iii) of total grafting of the residual NCO functions with functions that react with the NCO functions by means of polyfunctional compounds. The present invention also provides a silylated polyurethane composition that can be obtained by means of the process according to the invention, an adhesive composition comprising said silylated polyurethane composition and a self-adhesive item obtained from the adhesive composition according to the invention.
专利号:WO-2009135600-A1 优先权日:2008-05-07 标题:Catalysts for the synthesis of polyurethanes 发明人:LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN 权利人:BAYER MATERIALSCIENCE AG; LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN 摘要:The invention relates to novel catalysts for the synthesis of polyurethanes, represented by general formula (I) or (II), or compounds obtained by reacting a metal salt of the metals magnesium, calcium, yttrium, lanthanum, titanium, zirconium, manganese, iron, cobalt, zinc, aluminium, tin, comprising an anion from the group fluoride, chloride, bromide, sulphonate, trifluoromethanesulphonate, methanesulphonate, benzolsulphonate, para-toluenesulphonate, carboxy-C1-C10-alkyl, carboxy-C3-C10-cycloalkyl, carboxy- C2-C10-alkenyl, C1-C10-alkoxy, acetylacetonate, trifluoroacetlyacetonate or hexafluoroacetylacetonate, with N-heterocyclic compounds of general structure I; or with N-heterocyclic compounds of general structure II; or with N-heterocyclic compounds of general structure III.
专利号:US-9597327-B2 优先权日:2005-05-25 标 题:Synthesis of (R)-N-methylnaltrexone 发明人:DOSHAN HAROLD D; PEREZ JULIO 权利人:PROGENICS PHARM INC 摘要:This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.
专利号:US-2003130433-A1 优先权日:2001-10-30 标题 :Process for the production of graft polymers 发明人:WENZ ECKHARD; BUCHHOLZ VERA; EICHENAUER HERBERT; WOLF UDO; BORN RALF-JURGEN; JANSEN ULRICH; DIETZ WOLFGANG 摘要:A process of preparing a graft polymer (e.g., an ABS graft copolymer), which involves determining the concentration of at least one reaction component during the course of the reaction by means of Raman spectroscopy, is disclosed. The process, more particularly, comprises: (a) synthesizing the graft polymer from a reaction mixture comprising reactive components (e.g., monomers such as styrene and acrylonitrile, and a graft base); (b) analyzing the reaction mixture, at intervals, during the synthesis of the graft polymer, by means of Raman spectra; (c) recording the results of the Raman spectra analysis; (d) determining the concentration of at least one of said reactive components (e.g., styrene) by means of spectral evaluation of the recorded Raman spectra; and (e) terminating the synthesis reaction of the graft polymer when the concentration of at least one of the reactive components has reached a predetermined concentration value.
专利号:US-2024082118-A1 优先权日:2021-05-19 标 题:Topical compositions and methods of preparing the same 发明人:ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION 权利人:LANDA LABS 2012 LTD 摘要:There is disclosed a composition comprising a water-insoluble thermoplastic compound capable of stimulating collagen synthesis (CSSC), the CSSC having a molecular weight of more than 0.6 kDa and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less and a viscosity of 107 mPa·s or less. The nano-elements of CSSC can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon their application to a surface to be treated therewith. Methods for preparing the compositions and uses thereof are also provided.
[参考文献]: A Izri, Et Al. [参考文献]: Bull Soc Pathol Exot. 2001 Aug;94(3):280-3. [参考文献]: B Ballantyne, Et Al. The Acute Toxicity And Primary Irritancy Of 2-Ethyl-1,3-Hexanediol. Vet Hum Toxicol. 1985 Dec;27(6):491-5. [参考文献]: J P Van Miller, Et Al. Repeated Exposure Toxicity Of 2-Ethyl-1,3-Hexanediol By Cutaneous Applications To The Rat For 9 And 90 Days. Vet Hum Toxicol. 1995 Feb;37(1):33-6. [参考文献]: L C Rutledge, Et Al. Tests Of Repellents Against Diamanus Montanus (Siphonaptera: Ceratophyllidae). J Med Entomol. 1982 Jul 28;19(4):361-5. [参考文献]: L L Robert, Et Al. Comparative Sensitivity Of Four Anopheles (Diptera: Culicidae) To Five Repellents. J Med Entomol. 1991 May;28(3):417-20.
合成参考文献
摘要:Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966., -(508), 1966 摘要:Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 591 摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118 摘要:Schafer, E. W., Jr., W. A. Bowles Jr., and J. Hurlbut. 1983. The acute oral toxicity and repellency and hazard potential of 998 chemicals to one or more species of wild and domestic birds. Archives of Environmental Contamination and Toxicology 12:355-382. 摘要:Journal of the American College of Toxicology 13(6):418-436, 1994