CAS: 15903-94-3; 6-(Benzyloxy)-1H-Indole

相似化合物

92855-64-6 933474-39-6 92962-50-0

上下游产品

6-(苄氧基)-1H-吲哚-2-羧酸 6-(Benzyloxy)-1H-Indole-2-Carboxylic Acid 40047-22-1
6-羟基吲哚 6-Hydroxy-1H-Indole 2380-86-1
6-Benzyloxy-Indole-2-Carboxylic Acid Ethyl Ester 40047-20-9

3-苄氧基苯胺置于sodium Tetrahydroborate,三氯化硼,Zinc(II) Chloride体系中,用 1,4-二氧六环,水,苯 用作溶剂,化学反应 2.5H,反应生成6-苄氧基吲哚
参考文献:Nimtz,Manfred; Haefelinger,Guenter,Liebigs Annalen Der Chemie,1987,P. 765-770
标题:Nimtz,Manfred; Haefelinger,Guenter,Liebigs Annalen Der Chemie,1987,P. 765-770

专利信息

专利号:US-2022298204-A1
优先权日:2019-07-05
标题 :Synthesis of a-amanitin and its derivatives
发明人：SIEGERT MARY-ANN; KNITTEL CAROLINE HERTA; SÃœSSMUTH RODERICH
权利人:PURE BIOORGANICS SIA
摘要:The present invention relates to the chemical synthesis of α-amanitin and its derivatives. The present invention also relates to intermediate products of the α-amanitin synthesis.

专利号:EP-3792250-A1
优先权日:2019-09-13
标题:Synthesis of alpha-amanitin and its derivatives
发明人：SIEGERT MARY-ANN; KNITTEL CAROLINE HERTA; SÃœSSMUTH RODERICH
权利人:PURE BIOORGANICS SIA
摘要:The present invention relates to the chemical synthesis of α-amanitin and its derivatives. The present invention also relates to intermediate products of the α-amanitin synthesis.

专利号:US-9969685-B2
优先权日:2016-09-28
标 题 :Enantioselective synthesis of pyrroloindole compounds
发明人：SCHMIDT MICHAEL ANTHONY
权利人:BRISTOL MYERS SQUIBB CO
摘要:Compounds according to formula (I) or (II), wherein R 1 , R 2 , and R 3 are as defined in the specification, are versatile intermediates for the synthesis of DNA minor groove binder-alkylators having a cyclopropapyrroloindole (CPI) or seco-CPI alkylating subunit.

专利号:US-12378196-B2
优先权日:2018-12-11
标 题 :Synthesis of (S)-6-hydroxytryptophan and derivatives thereof
发明人：SIMON WERNER; WERNER-SIMON SUSANNE; MüLLER CHRISTOPH
权利人:HEIDELBERG PHARMA RES GMBH
摘要:The present invention relates to novel methods and compounds for synthesizing amanitin derivatives. The invention in particular relates to methods for synthesizing (S)-6-hydroxy-tryptophan derivatives which can be used as building blocks for synthesizing amanitin derivatives or amatoxin drug conjugates. The invention further relates to intermediate compounds of said synthesis pathways for use in amanitin derivative and amatoxin drug conjugate synthesis, and to the use of particular catalysts suited for mediating said synthesis pathways.

专利号:US-2008280855-A1
优先权日:2005-06-22
标 题 :Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles
发明人：CHIESA MARIA VITTORIA; PALMER ANDREAS; BUHR WILM; ZIMMERMANN PETER JAN; BREHM CHRISTOF; SIMON WOLFGANG-ALEXANDER; POSTIUS STEFAN; KROMER WOLFGANG; ZANOTTI-GEROSA ANTONIO
权利人:NYCOMED GMBH
摘要:The invention relates to a process for the synthesis of compounds of the formula 1-a and compounds of the formula 1-b. n n n n n n n n n n The compounds of the formula 1-a and the compounds of the formula 1-b, in which the substituents R1, R2, R3, and Ar have the meanings indicated in the description, are valuable intermediates for the preparation of pharmaceutically active compounds.

专利号:WO-2007141253-A1
优先权日:2006-06-07
标 题 :Process for the production of intermediates for the preparation of tricyclic imidazopyridines
发明人：PALMER ANDREAS; BUHR WILM; ZIMMERMANN PETER JAN; BREHM CHRISTOF; CHIESA MARIA VITTORIA; ZANOTTI-GEROSA ANTONIO
权利人:NYCOMED GMBH; PALMER ANDREAS; BUHR WILM; ZIMMERMANN PETER JAN; BREHM CHRISTOF; CHIESA MARIA VITTORIA; ZANOTTI-GEROSA ANTONIO
摘要:The invention relates to a process for the synthesis of compounds of the formula (1-a) and compounds of the formula (1-b). The compounds of the formula 1-a and the compounds of the formula 1-b, in which the substituents R1, R2, R3, and Arom have the meanings indicated in the description, are valuable intermediates for the preparation of pharmaceutically active compounds.