邻氨基苯甲酸置于盐酸,氯体系中,用 水 用作溶剂,以89%的收率获得2-氨基-3,5-二氯苯甲酸 参考文献:Synthesis And Insecticidal Activity Of 6,8-Dichloro-Quinazoline Derivatives Containing A Sulfide Substructure 标题:Synthesis And Insecticidal Activity Of 6,8-Dichloro-Quinazoline Derivatives Containing A Sulfide Substructure 摘要:摘要:合成了一系列带有硫化物基团的6,8-二氯喹唑啉衍生物,并通过1H NMR,13C NMR,Ir和元素分析进行了表征.所有化合物均在体外对小菜蛾进行了杀虫活性测试.结果表明,合成的化合物具有非常好的杀虫活性.其中,Vc,Vi,Vj,Vk和vm的活性分别为75%,85%,80%,70%和63%.这些化合物可能有用作杀虫剂. Doi:10.2478/s11696-014-0540-Z
专利号:US-5783577-A 优先权日:1995-09-15 标题 :Synthesis of quinazolinone libraries and derivatives thereof 发明人:HOUGHTEN RICHARD A; OSTRESH JOHN M 权利人:TREGA BIOSCIENCES INC 摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.
专利号:US-4713383-A 优先权日:1984-10-01 标 题:Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses 发明人:FRANCIS JOHN E; GELOTTE KARL O 权利人:CIBA GEIGY CORP 摘要:[1,2,4]triazolo[1,5-c]quinazoline compounds of the formula wherein R1 is optionally substituted phenyl, pyridyl, furyl thienyl, dihydro or tetrahydro furanyl or thienyl, pyranyl, or 0-ribofuranosyl; R2 is hydrogen or lower alkyl; X is oxygen or NR3, R3 is as defined in the claims, and ring A is unsubstituted or substituted as set forth in the claims. The compounds wherein X is N-R3 are especially useful as adenosine antagonists and for the treatment of asthma. The compounds wherein X is oxygen are useful as benzodiazepine antagonists and as intermediates in the synthesis of the compounds wherein X is N-R3.
专利号:WO-9710221-A1 优先权日:1995-09-15 标 题:Synthesis of quinazolinone libraries 发明人:HOUGHTEN RICHARD A; OSTRESH JOHN M 权利人:TORREY PINES INST 摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.
专利号:WO-9811438-A1 优先权日:1996-09-13 标题 :Synthesis of quinazolinone libraries and derivatives thereof
专利号:CN-102838481-A 优先权日:2011-06-23 标 题 :Synthesis of 3,5-Dichlorobenzoyl Chloride
参考文献:10.1007/s00425-010-1105-1 摘要:Serrano M, Hubert DA, Dangl JL, Schulze-Lefert P, Kombrink E. A chemical screen for suppressors of the avrRpm1-RPM1-dependent hypersensitive cell death response in Arabidopsis thaliana. Planta. 2010 Feb 07;231(5):1013–23. doi: 10.1007/s00425-010-1105-1.