CAS: 7169-34-8; Benzofuran-3(2H)-One

相似化合物

6272-26-0 15832-09-4 5380-80-3

上下游产品

Phenoxyacetyl chloride 2.3-dihydrobenzofuran (2-hydroxy-phenyl)-(3-phenyl-oxiranyl)-methanone phosphoric acid dibenzyl ester 3-methyl-benzofuran 3-ethylbenzo[b]furan (Z)-2-(4-nitrobenzylidene)benzofuran-3(2H)-one 3-Phenylbenzofuran

阿司匹林置于氯化亚砜,三氟乙酸体系中,用 乙醚,二氯甲烷,苯 作为反应溶剂,化学反应 0.5H,反应生成 3-苯并呋喃酮
参考文献:氧杂环的研究:第1部分:某些芳基重氮酮的酸催化和光化学反应
标题:氧杂环的研究:第1部分:某些芳基重氮酮的酸催化和光化学反应
摘要:三氟乙酸催化的2-甲氧基苯基重氮甲基甲酮(4A),2-乙酰氧基苯基重氮甲基甲酮(4B)和3-(2-茴香基)-∞-重氮-2-丙酮(11)导致香豆烷酮(6)和3-苯并二氢吡喃酮的形成(12),而4-(2-茴香基)-∞-重氮-2-丁酮(16)提供了苯并[b]-1-氧杂-3-酮(17)和5-甲氧基-2-四氢萘酮(18)产量适中.所述重氮酮(4A,11和16)的光化学分解产生产物,这取决于底物中存在的侧链的长度.
DOI:10.1016/0040-4020(89)80142-5

专利信息

专利号:US-4835276-A
优先权日:1986-07-03
标 题 :Preparation of n-formamidoyl[(s)-1-t-butoxy-3-methyl-2-amino)]1,2,3,4 tetrahydrobenzo [b]furo [2,3-c]pyridine and derivatives
发明人：VOLANTE RALPH P; DESMOND RICHARD; SHINKAI ICHIRO
权利人:MERCK & CO INC
摘要:The present invention is directed to an enantioselective synthesis of 1,3,4,6,7,12b(S)-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin-2-one which is an intermediate in the production of the α 2 -adrenergic antagonist (2R,12bS)-N-(1,3,4,6,7,12-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin-2-yl)-N-methyl-2-hydroxy-ethanesulfonamide hydrochloride.

专利号:US-4429138-A
优先权日:1977-10-21
标题 :Process for the synthesis of 5-methoxy-psoralen
发明人：GOUPIL JEAN-JACQUES
权利人:GOUPIL JEAN JACQUES
摘要:A pharmaceutical formulation comprising 5-methoxy psoralen, which is useful in the treatment of psoriasis and other skin disorders, is disclosed herein. 5-Methoxy psoralen may be synthesized from phloroglucinol by a five step process which is also disclosed.

专利号:US-9751851-B2
优先权日:2013-09-20
标 题:Molecules and compositions that inhibit gram negative bacteria and their uses
发明人：BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; CONRAD-MILLER LAURA C; O'LOUGHLIN COLLEEN T
权利人:UNIV PRINCETON; BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; MILLER LAURA C; O'LOUGHLIN COLLEEN T
摘要:Antivirulence strategies to combat Pseudomonas aeruginosa , are described. One strategy encompasses synthesis of a series of compounds that inhibit the production of pyocyanin, a redox-active virulence factor produced by this pathogen. A related strategy encompasses synthesis of compounds that inhibit the two P. aeruginosa quorum-sensing receptors, LasR and RhlR, inhibit production of pyocyanin, and inhibit biofilm formation.

专利号:US-11505534-B2
优先权日:2017-05-16
标题:Highly diastereoselective construction of the 4,5-spirocycle via palladium-catalyzed intramolecular alkenylation
发明人：XIE JIAXIN; DONG GUANGBIN
权利人:UNIV CHICAGO
摘要:A diastereoselective method of preparing benzofuran-based 4,5-spirocycles via metal catalyzed alkenylation is described. The method can be used to provide compounds containing the benzofuranone-4,5-spirocyclic motif of the phainanoids, a class a natural products having immunosuppressive activity. Synthetic analogs of phainanoids, e.g., compounds that mimic the structure of the “westernâ€? part of the structure of the phainanoids and that contain the benzofuranone-4,5-spirocycle are described, as well as their synthetic intermediates, and their methods of synthesis.

专利号:EP-1491540-B1
优先权日:2001-03-30
标题 :Intermediates useful for the synthesis of pyridazinone aldose reductase inhibitors

专利号:US-6603025-B1
优先权日:1999-11-16
标题:Method of production of benzofuranone oximes
发明人：LANTZSCH REINHARD; GAYER HERBERT; GERDES PETER; HUEBSCH WALTER; MULDER LUBBERTUS; GALLENKAMP BERND; DECKER MATTHIAS
权利人:BAYER AG
摘要:The present invention relates to a novel process for preparing known benzofuranone oximes, and to a novel process for preparing known benzofuranyl alkanoates which are used as intermediates in the synthesis sequence.