2,3,6-三氟苯腈置于硫酸体系中,化学反应生成2,3,6-三氟苯甲酸 参考文献:2,3-Difluoro-6-Nitrobenzonitrile And 标题:2,3-Difluoro-6-Nitrobenzonitrile And 摘要:本发明描述了新型中间体2,3-二氟-6-硝基苯腈和2-氯-5,6-二氟苯腈,以及它们的制备方法和它们在制备2,3,6-三氟苯甲酸方面的优势用途,而2,3,6-三氟苯甲酸则是制备杀虫剂和抗菌剂的有价值的中间体.根据本发明,所述中间体是通过氟/氰交换和随后的脱硝氯化从2,3,4-三氟硝基苯制备而成.2,3,6-三氟苯甲酸可以通过文献已知的简单氯/氟交换和随后的水解制备而成,这个过程整体上在工业上具有优势和经济上有利.
专利号:US-6180830-B1 优先权日:1995-11-08 标题 :Method for preparing a bimetallic ruthenium/tin catalyst and a process for the synthesis of aldehydes 发明人:JACQUOT ROLAND 权利人:RHODIA CHIMIE SA 摘要:The present invention relates to a new process for the preparation of a bimetallic ruthenium/tin catalyst. The process for the preparation of a bimetallic ruthenium/tin catalyst according to the invention is characterised by the fact that it consists in carrying out the reduction of a ruthenium complex having an electrovalency of -4 and a coordination number of 6, the ligands being either a halogen atom or an anion or a tin halide. The catalyst is further employed for the preparation of aldehydes by reduction, in the vapor phase, of carboxylic acids, esters and anhydrides.
专利号:WO-2024126692-A1 优先权日:2022-12-15 标题 :Peracid promoters in the iridium-catalyzed hydrosilylation synthesis of haloalkylorganosilanes 发明人:SCHOLZ HENRIK; KROKE EDWIN; KRAUSHAAR KONSTANTIN; GLATZER HOLGER JÜRGEN; LEWIS KENRICK MARTIN; WAGNER ROLAND 权利人:MOMENTIVE PERFORMANCE MAT GMBH 摘要:The present invention is directed at a process for producing a compound of Formula (I): (R1)y(R2O)3-ySiCH2CHR3CR4R5X comprising reacting (a) an olefinic halide; (b) an alkoxysilane; (c) a catalytically effective amount of iridium-containing catalyst; and (d) a reaction-promoting effective amount of a peroxycarboxylic acid to produce the product of Formula (I).
专利号:EP-4634196-A1 优先权日:2022-12-15 标题 :Peracid promoters in the iridium-catalyzed hydrosilylation synthesis of haloalkylorganosilanes
专利号:US-9217012-B2 优先权日:2009-04-08 标题 :Inhibitors of protein tyrosine phosphatases 发明人:ZHANG ZHONG-YIN; ZHANG SHENG 权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP 摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
专利号:EP-0539274-B1 优先权日:1991-10-24 标题 :Method for the synthesis of aldehydes and of their derivatives
专利号:JP-3615811-B2 优先权日:1991-10-24 标 题 :Catalysts for the synthesis of aldehydes and their derivatives
[参考文献]: V Mukherjee, Et Al. Ftir And Raman Spectra And Optimized Geometry Of 2,3,6-Tri-Fluorobenzoic Acid Dimer: A Dft And Sqmff Study. Spectrochim Acta A Mol Biomol Spectrosc. 2010 Nov;77(4):787-94.
合成参考文献
摘要:Zhang, M.; Su, W., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 3, 125. 摘要:Zhang, H.; Liu, C.; Lei, A., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 144. 摘要:Nelson, D. J., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 2, 281. 摘要:Franck, X.; Durandetti, M., Science of Synthesis: Knowledge Updates, (2024) 3, 317.