专利号:US-2022289684-A1 优先权日:2019-08-29 标 题:Benzimidazole substitution-based phenyl n-butyramide compound and preparation method therefor 发明人:SHEN JINGSHAN; SUN CHANGLIANG; ZHU FUQIANG; ZHANG JUNCHI; LI RUI 权利人:TOPHARMAN SHANGHAI CO LTD; SHANGHAI INST OF MATERIAMEDICA CHINESE ACADEMY OF SCIENCES; TOPHARMAN TANCHENG CO LTD 摘要:The present disclosure relates to a benzimidazole-substituted phenyl-n-butyramide-based compound and the preparation method thereof. The method of the present disclosure avoids nitration reaction and polyphosphoric acid cyclization reaction, and avoids the generation of a large amount of waste acid reaction solution from the source. The synthesis method embodied in the invention has the advantages of simplicity and high efficiency, mild conditions and few pollutants, etc., and is suitable to be developed as a green and sustainable production process.
专利号:US-11040939-B1 优先权日:2020-06-23 标 题 :N-transfer reagent and method for preparing the same and its application 发明人:CHOU HO-HSUAN; LU GUAN-HAN; HSUEH HSIAO-CHIN; HUANG TZU-CHIA 权利人:UNIV NAT CHENG KUNG 摘要:Provided are a novel N-transfer reagent and a method for preparing the same and its application. The N-transfer reagent is represented by the following Formula (I): n n n n n n n n n n The various novel N-transfer reagents of the present invention can be quickly prepared by employing different nitrobenzene precursors. The N-transfer reagents can directly convert a variety of amino compounds into diazo compounds under mild conditions. Particularly, the N-transfer reagents can facilitate the synthesis of the diazo compounds. The application of synthesizing diazo compounds of the present invention can greatly decrease the difficulty in operation, increase the safety during experiments, reduce the cost of production and the environmental pollution, and enhance the industrial value of diazo compounds.
专利号:CN-1935376-A 优先权日:2006-10-17 标题:A catalyst and its application in the synthesis of 4-nitro-3-methylbenzoic acid
专利号:CN-117947434-A 优先权日:2023-11-30 标题 :Method for electrochemical synthesis of chlorine-containing aromatic and heterocyclic compounds using hydrogen chloride as chlorine source
专利号:CN-115010621-B 优先权日:2022-07-21 标题:A kind of synthesis method of 4-bromo-3-methylbenzonitrile
专利号:RU-2126006-C1 优先权日:1993-07-29 标 题:Tricyclic diazepine vasopressin and oxytocin antagonists, method of their synthesis, pharmaceutical composition, method of treatment
摘要:2024 Emergency Response Guidebook, 摘要:National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.