CAS: 36404-88-3; 2-Chloronicotinaldehyde

相似化合物

1452-94-4 2942-59-8 6602-54-6

上下游产品

CAS号109-09-1 2-氯吡啶 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号6602-54-6 2-氯烟腈 | CAS号2591-86-8 1-甲酰哌啶 | CAS号7226-23-5 N,N-二甲基丙烯基脲 | CAS号2942-59-8 2-氯烟酸 | CAS号49609-84-9 2-氯-3-吡啶羧酸 | CAS号52200-48-3 3-溴-2-氯吡啶 | CAS号109-94-4 甲酸乙酯 | CAS号73583-37-6 4-溴-2-氯吡啶 | CAS号104842-73-1 3-Pyridinecarbo... | CAS号59944-76-2 噻吩并[2,3-B]吡啶-2-甲酸 | CAS号35567-32-9 2-(二甲基氨基)烟醛 | CAS号59944-78-4 噻吩并[2,3-b]吡啶-2-羧酸乙酯 | CAS号215872-96-1 2-CHLORONICOTIN... | CAS号18354-56-8 Ethanone,1-thie... | CAS号89581-84-0 2-氯-3-氯甲基吡啶 | CAS号852063-32-2 ETHYL 4-(2-CHLO... | CAS号71255-09-9 2-甲氧基-3-吡啶醛 | CAS号68618-36-0 3-溴-1H-吡唑并[3,4B]吡啶

2-氯吡啶置于丙烯脲,正丁基锂,二异丙胺,盐酸,Ammonium Hydroxide体系中,用 四氢呋喃,水,N,N-二甲基甲酰胺 用作溶剂,化学反应 5.58H,反应生成2-氯-3-吡啶甲醛
参考文献:Wo2006/57922
标题:Wo2006/57922

专利信息

专利号:US-2006025421-A1
优先权日:2004-06-25
标 题:Pyridyl piperazines for the treatment of CNS disorders
发明人：BRODNEY MICHAEL A
权利人:PFIZER
摘要:This invention is directed to compounds of Formula I and to pharmaceutical compositions comprising the compound of Formula I. n n where the dashed line represents an optional double bond; and where n is 1 or 2, and Ar 1 , Ar 2 , . . . and Z are as defined in the specification. The invention is also directed to a method of treating a disorder or condition that can be treated by altering serotonin-mediated neurotransmission, such as migraine, headache, cluster headache, anxiety, depression, etc. This invention is also directed to intermediates useful in the synthesis of compounds of Formula I.

专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人：FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

专利号:US-11702652-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2009264300-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2020216836-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries