CAS: 6972-71-0; 4,5-Dimethyl-2-Nitroaniline

该化合物是一种有机化合物,其分子式为C8H10N2O2, 其特点是硝基组和一个在二甲基替代苯环上的矿物质组,该化合物主要用作染料,颜料和其他特殊化学品的合成中间体,其定义明确的结构和活性使其对产生zo染料和其他含氮衍生物具有价值.二甲基替代可增强稳定性和影响芳香环的电子特性,促进受控的功能化.它具有高纯度,确保合成应用的性能一致.建议适当处理,因为其可能具有对光和热的敏感性.

英文名称4,5-Dimethyl-2-Nitroaniline
中文名称4,5-二甲基-2-硝基苯胺
IUPAC名称4,5-dimethyl-2-nitroaniline
其它别名2-硝基-4,5-二甲基苯胺; 6-Nitro-3,4-Xylidine
CAS编号6972-71-0
MFCD编号:MFCD00007811
EINECS号:230-211-5
FDA UNII编号:O1U4USE3TJ
分子式:C8H10N2O2
分子量:166.18
产品CID: 1692748
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
产品信息参考
InChIKey: PINGKGKKUSYUAW-UHFFFAOYSA-N
InChI=1S/C8H10N2O2/c1-5-3-7(9)8(10(11)12)4-6(5)2/h3-4H,9H2,1-2H3…
计算化学: 氢键受体数3.0氢键供体数1.0可旋转键数1.0

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别急性毒性类别4(吸入)
急性毒性类别4(经皮)
急性毒性类别4(经口)
皮肤腐蚀/刺激类别2
严重眼刺激类别2
特定目标器官毒性 - 单次接触类别3
警示词Warning(警告)
危险描述H332 |吸入有害.
H312 |皮肤接触有害.
H302 |吞咽有害.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H335 |可能引起呼吸道刺激.
防范说明P264-P270-P330-P405-P501
危险等级6.1
UN编号2811.0
危险品标志Xn,Xi
风险等级Irritant
包装等级Ⅲ
安全声明26-36
危险类别码20/21/22-36/37/38
WGK Germany3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

合成工艺路线路线简述

(4,5-Dimethyl-2-Nitro-Phenyl)-Carbamic Acid Ethyl Ester置于sodium Hydroxide体系中,化学反应生成 4,5-二甲-2-硝基苯胺
参考文献:Matsukawa; Shirakawa,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1949,Vol. 69,P. 493,495
标题:Matsukawa; Shirakawa,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1949,Vol. 69,P. 493,495

海关参考信息

2902300000-甲苯
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:WO-2021038419-A1
优先权日:2019-08-23
标题 :Kinase inhibitors and methods of synthesis and treatment
发明人：ZAVORONKOVS ALEKSANDRS; IVANENKOV YAN; POLYKOVSKIY DANIIL; ALIPER ALEKSANDR
权利人:INSILICO MEDICINE IP LTD
摘要:Compounds that function as kinase inhibitors are provided. The kinase inhibitors can have any structure of the formulae provided herein, such as shown for Compounds 1-4. A pharmaceutical composition can include: the compound of one of the embodiments; and a pharmaceutically acceptable carrier having the compound. A method of inhibiting a kinase can include: providing the compound of one of the embodiments described herein to the kinase such that the kinase is inhibited. The methods can include inhibiting DDR1 and/or DDR2, and thereby providing a modulation or decrease in the activity of DDR1 and/or DDR2. This decrease in DDR1 and/or DDR2 activity can be used as therapy to treat conditions related to DDR1 and/or DDR2 activity, such as fibrosis, cancer, and others.

专利号:RU-2119916-C1
优先权日:1995-01-05
标题:Method of synthesis of substituted 1,10-phenanthrolines

专利号:CN-119080702-A
优先权日:2024-08-29
标题 :Synthesis method of environment-friendly 5, 6-dimethyl benzoimidazole