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CAS号1204417-39-9 N,N'-(2,2'-(met... | CAS号106-93-4 1,2-二溴乙烷 | CAS号74-89-5 氨基甲烷 | CAS号51-75-2 氮芥 | CAS号107-06-2 1,2-二氯乙烷 | CAS号80-73-9 1,3-二甲基-2-咪唑啉酮 | CAS号61797-48-6 N-methyl-N-[2-[...1,4,7-Trimethyl-1,7-Bis(P-Tolylsulfonyl)-1,4,7-Triazaheptane置于lithium Aluminium Tetrahydride体系中,用 乙二醇二甲醚 用作溶剂,以91%的收率获得n,N',N"-三甲基二乙烯三胺
参考文献:合成聚n,N'-二甲基乙二胺的途径
标题:合成聚n,N'-二甲基乙二胺的途径
摘要:通过容易获得的n-甲胺或n,N'-二甲基乙二胺与n-甲基-N-(4-甲苯磺酰基)碘乙胺的烷基化,已经实现了聚-N,N'-二甲基乙二胺的简单高产率合成.
Doi:10.1016/0040-4039(92)88177-7
专利信息
专利号:US-4472568-A
优先权日:1981-11-12
标 题:Process for the preparation of polyamines from N-monoaryl-N',N'-dialkyl urea compounds and their use for the synthesis of polyurethanes
发明人:RASSHOFER WERNER; GROEGLER GERHARD
权利人:BAYER AG
摘要:This invention relates to an improved process for the preparation of aromatic polyamines containing urethane and/or biuret and/or urea and/or isocyanurate groups and preferably also ether groups by the hydrolysis of poly-N-monoaryl-N',N'-dialkyl urea compounds (1-aryl-3,3-dialkyl ureas). The ureas are obtained by the reaction of secondary aliphatic, cycloaliphatic or saturated heterocyclic amines with divalent to tetravalent isocyanate compounds containing isocyanate end groups attached to aromatic residues. The ureas correspond to the general formula: wherein R1, R2 denote alkyl or cycloalkyl groups, or together form a ring and A denotes a divalent to tetravalent residue attached to the ureas by aromatic groups. Hydrolysis is carried out in the presence of water and up to two equivalents of a base containing hydroxide ions and/or up to two equivalents of a compound containing tertiary amino groups, optionally in the presence of solvents. The use of the polyamines obtained by this process for the synthesis of polyurethanes is also described.
专利号:WO-2025045973-A1
优先权日:2023-08-31
标题 :Synthesis of lanifibranor intermediate
发明人:BOUBIA BENAÃ?SSA; GONZALEZ JÉRÔME; BELL FRÉDÉRIC
权利人:INVENTIVA
摘要:The present disclosure is directed to a process for preparing a compound of formula (I), which comprises a palladium-free coupling reaction between N-(4-chloro-2-iodo-phenyl)-1,3-benzothiazole-6-sulfonamide and methyl 5-hexynoate in the presence of a copper catalyst.
专利号:US-2011230343-A1
优先权日:2008-10-24
标题 :Method for the Manufacture of Microparticles Comprising an Effect Substance
发明人:SCHROERS MICHAEL; DYLLICK-BRENZINGER RAINER; MERK MICHAEL; BARG HEIKO
权利人:BASF SE
摘要:A subject matter of the present invention is a process for the preparation of effect compound-comprising microparticles M comprising A) the formation of a crude suspension of microparticles A by means of enzymatic polyester synthesis in an inverse miniemulsion comprising enzyme, effect compound and polyester monomers; and B) the polymerization of wall monomers from the group consisting of ethylenically unsaturated monomers, polyisocyanates and polyepoxides in the crude suspension of microparticles A. Furthermore, the present invention relates to microparticles M which can be obtained by means of the process according to the invention and also to an agrochemical formulation comprising microparticles M. In addition, the present invention relates to the use of microparticles M prepared according to the invention as component in colorants, cosmetics, drugs, biocides, plant protection agents, fertilizers, additives for food or animal fodder, or auxiliaries for polymers, paper, textiles, leather, detergents or cleaners. Finally, the invention also relates to a method for combating undesirable plant growth, to a method for combating undesirable insect or acarid infestation on plants and/or for combating phytopathogenic fungi, and to seeds treated with the agrochemical formulation.
专利号:US-2023271983-A1
优先权日:2020-07-29
标题 :Functionalized isonitriles and products, preparation and uses thereof
发明人:SOTELO PÉREZ EDDY; AZUAJE GUERRERO JHONNY ALBERTO; MAJELLARO MARIA
权利人:UNIV SANTIAGO COMPOSTELA
摘要:The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.
专利号:US-6583182-B1
优先权日:1995-06-26
标 题:Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy and diagnosis
发明人:WINCHELL HARRY S; KLEIN JOSEPH Y; SIMHON ELLIOT D; CYJON ROSA L; KLEIN OFER; ZAKLAD HAIM
权利人:CHELATOR LLC
摘要:This invention involves synthesis and use of a class of compounds with chelation affinity and selectivity for first transition series elements. Administration of the free or conjugated compound, or physiological salts of the free or conjugated compound, results in decrease in the in vivo bioavailability of first transition series elements and/or removal from the body of first transition series elements and elements with similar chemical properties. These characteristics make such compounds useful in the management of diseases associated with a bodily excess of first transition series elements and elements with similar chemical properties. This invention demonstrates that such compounds inhibit mammalian, bacterial, and fungal cell replication and are therefore useful in the treatment of neoplasia, infection, inflammation, immune reponse, and in termination of pregnancy. Since these compounds are capable of descreasing the in vivo availability of tissue iron they are useful in management of free radical mediated tissue damage, and oxidation mediated tissue damage. When combined with radioisotopic or paramagnetic cations of first transition series elements, or elements with chemical properties similar to those of first transition series elements, prior to their administration, the resulting complexes are useful as diagnostic agents in nuclear medicine and magnetic resonance imaging (MRI).