CAS: 1850-14-2; Tetramethylorthocarbonate

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CAS号124-41-4 甲醇钠 | CAS号545-06-2 三氯乙腈 | CAS号76-06-2 氯化苦 | CAS号67-56-1 甲醇 | CAS号1122-85-6 氰酸苯酯 | CAS号594-42-3 全氯甲硫醇 | CAS号75-15-0 二硫化碳 | CAS号10450-11-0 N-环己基-2-苯并噁唑胺 | CAS号616-38-6 碳酸二甲酯 | CAS号67-56-1 甲醇 | CAS号100-66-3 苯甲醚 | CAS号100-68-5 茴香硫醚 | CAS号87-41-2 苯酞 | CAS号26384-75-8 2-methoxy-1,3-b... | CAS号24471-99-6 1,4,6,9-tetraox... | CAS号597-72-8 四丙氧基甲烷 | CAS号531-59-9 7-甲氧基香豆素

甲醇置于vanadia体系中,180.0 °C,1.8 Mpa 条件下,反应 0.1H,以86%的收率获得原碳酸四甲酯
参考文献:一种催化甲醇直接氧化酯化制四甲氧基甲烷 的方法
标题:一种催化甲醇直接氧化酯化制四甲氧基甲烷 的方法
摘要:本发明公开了一种催化甲醇直接氧化酯化制四甲氧基甲烷的方法,属于制备四甲氧基甲烷的领域,具体为:以氧气或空气为氧源,以甲醇为底物和溶剂,在催化剂作用下,甲醇经过氧化酯化生成四甲氧基甲烷.该方法原料利用率高,催化剂廉价易得,易回收,可循环使用,且易与产品分离.得到的产品性能优异,纯度高.此技术路线对于缓解甲醇产能过剩,减少对剧毒化学品的依赖,具有重要的意义.

专利信息

专利号:US-12240835-B2
优先权日:2018-09-18
标题:Substituted benzamides as intermediates in the synthesis of inhibitors of tyrosine kinase enzymatic activity
发明人：ROMERO F ANTHONY; KIRSCHBERG THORSTEN A; HALCOMB RANDALL; XU YINGZI
权利人:TERNS PHARMACEUTICALS INC
摘要:Provided herein are compounds, preferably compounds inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, compositions thereof, and methods of their preparation, and methods of inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, and methods for treating diseases wherein modulation of BCR-ABL1 activity prevents, inhibits, or ameliorates the pathology and/or symptomology of the disease. Intermediates such as compounds of Formula (S23), which are useful in the synthesis of compounds inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, are also provided.

专利号:US-9127123-B2
优先权日:2010-05-27
标 题:Membrane enhanced polymer synthesis
发明人：LIVINGSTON ANDREW GUY; GAFFNEY PIERS ROBERT JAMES; VASCONCELOS RENATO CAMPOS
权利人:LIVINGSTON ANDREW GUY; GAFFNEY PIERS ROBERT JAMES; VASCONCELOS RENATO CAMPOS; IMP INNOVATIONS LTD
摘要:This invention relates to the synthesis of polymers. More specifically, the present invention relates to the synthesis of heterobifunctional polymers and polymers with narrow and mono-disperse molecular weight distributions, and especially to the application of membranes to the synthesis of these polymers.

专利号:US-11091445-B2
优先权日:2016-10-24
标题 :Compounds, process for obtaining the compounds, pharmaceutical composition, use of the compounds and method for treating psychiatric disorders and/or sleep disorders
发明人：RUCH WERNECK GUIMARÃES CRISTIANO; FELYPE ZANETI DE AZEVEDO HATYLAS; MASCARELLO ALESSANDRA; WATANABE DA COSTA RENATA; FREIRE TORRES RUSSO VALTER; MANNOCHIO DE SOUZA RUSSO ELISA
权利人:ACHE LABORATORIOS FARMACEUTICOS SA
摘要:The present disclosure relates to novel and inventive pharmacologically active benzimidazole derivative compounds, which surprisingly have high affinity for melatonin MT1 and MT2 receptors and low affinity for CYP450 complex enzymes, specially CYP1A2. The present invention also relates to novel and inventive routes of synthesis of these compounds, pharmaceutical compositions comprising the compounds and the use of these compounds in the treatment of individuals affected by psychiatric disorders and/or sleep disorders related to these receptors (specially depression, anxiety, circadian cycle disorders), in addition to a process for producing the composition.

专利号:WO-9511893-A1
优先权日:1993-10-27
标题 :Compounds and methods for synthesizing pantethine, pantetheine and derivatives thereof
发明人：PATIL GHANSHYAM
权利人:OCULON CORP
摘要:There is disclosed compounds and methods for the synthesis of pantethine, pantetheine, and derivatives thereof. The methods utilize crystalline derivatives of the above compounds as intermediates which readily permit purification by recrystallization, and thus allow the generation of highly pure products. The synthesis utilizes the 1,3-diol functional group present in pantothenic acid to produce the crystalline derivatives by formation of ketal intermediates. Subsequent hydrolisis of the ketal intermediates yields pantethine or pantetheine in highly pure form.

专利号:EP-1915358-B1
优先权日:2005-08-08
标题:Integrated method for the production of trioxane from formaldehyde
发明人：LANG NEVEN; STROEFER ECKHARD; STAMMER ACHIM; FRIESE THORSTEN; SIEGERT MARKUS; HASSE HANS; GRUETZNER THOMAS; BLAGOV SERGEJ
权利人:BASF SE
摘要:The invention relates to an integrated process for preparing trioxane from formaldehyde in which, in a first step, a stream A 1 comprising water and formaldehyde and a recycle stream B 2 consisting substantially of water and formaldehyde are fed to a trioxane synthesis reactor in which the formaldehyde is converted to trioxane to obtain a product stream A 2 comprising trioxane, water and formaldehyde. Stream A 2 and a recycle stream D 1 comprising trioxane, water and formaldehyde are fed to a first distillation column and distilled at a pressure in the range from 0.1 to 2.5 bar to obtain a stream B 1 enriched in trioxane, and the stream B 2 consisting substantially of water and formaldehyde. Stream B 1 is fed to a second distillation column and distilled at a pressure in the range from 0.2 to 17.5 bar to obtain a product stream C 2 consisting substantially of trioxane, and a stream C 1 comprising trioxane, water and formaldehyde. Stream C 1 is fed to a third distillation column and distilled at a pressure in the range from 1 to 10 bar to obtain the recycle stream D 1 comprising trioxane, water and formaldehyde, and a stream D 2 consisting substantially of water.

专利号:US-6822124-B2
优先权日:2000-11-24
标 题 :Method for producing alcoxylated carbonyl compounds by an anodic oxidation method using a cathodic coupled reaction for organic synthesis
发明人：PUETTER HERMANN; FISCHER ANDREAS
权利人:BASF AG
摘要:A method for producing alcoxylated carbonyl compounds of general formula (I) (compounds I): R<1>aR<2>C(OR<3>)b wherein R<1>, R<2 >represent hydrogen or C1-C6-alkyl, R<3 >independently means C1-C6-alkyl, a is 0 or 1, b 2 or 3 with the proviso that the sum of a and b is 3, by means of anodic oxidation of germinal dialcoxy compounds of general formula (II) (compounds II) wherein R<4>, R<5>, R<6>, R<7 >represent hydrogen or C1-C6-alkyl, R<5>, R<6 >represent C1-C6-alkyl or C1-C6-alcoxy, in the presence of a C1-C6-alkyl alcohol (compounds III). A usual compound (compound IV) is used as a cathodic depolarizer suitable for electrochemical oxidation. The anodic oxidation and cathodic reduction is carried out in an undivided electrolyte cell in the presence of C1-C6-alkyl alcohols.