CAS: 2450-53-5; (1R,3R,4S,5R)-3,5-Bis((3-(3,4-Dihydroxyphenyl)Acryloyl)Oxy)-1,4-Dihydroxy-3-Methylcyclohexane-1-Carboxylic Acid

该化合物是属于咖啡基丙酸家族的一种聚酚化合物,是丙酸和咖啡叶酸酯的酯,其特征为:三和五个基座上附着两种碳基酸组,通常存在于各种植物,特别是咖啡和某些水果中,有助于其抗氧化特性;该化合物展示了重要的生物活动,包括防炎,抗氧化剂和潜在的...

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上下游产品

CAS号1352319-04-0 3,3'-(((1R,2S,3... | CAS号139-85-5 原儿茶醛; 原二茶醛; 茶酚甲... | CAS号1352319-06-2 (1R,3R,4S,5R)-b... | CAS号1352319-08-4 3,3'-(((1R,2S,3... | CAS号1352319-05-1 (1R,3R,4S,5R)-1... | CAS号77-95-2 D-(-)-奎宁酸 | CAS号665-27-0 quino-1,5-lactone | CAS号331-39-5 咖啡酸 | CAS号77-95-2 D-(-)-奎宁酸

合成工艺路线路线简述

    1,5-Quinide置于哌啶,咪唑,4-二甲氨基吡啶,Pyridine Hydrofluoride,10% Pd(Oh)2 On C,水,氢气,Sodium Hydride,Caesium Carbonate,Sodium Hydroxide体系中,用 四氢呋喃,甲醇,N,N-二甲基甲酰胺,甲苯,Mineral Oil 用作溶剂,化学反应 272.25H,反应生成异绿原酸a
    参考文献:Total Synthesis Of 3,5-O-Dicaffeoylquinic Acid And Its Derivatives
    标题:Total Synthesis Of 3,5-O-Dicaffeoylquinic Acid And Its Derivatives
    摘要:We Report The First Total Synthesis Of 3,5-O-Dicaffeoylquinic Acid And Its Derivatives,3,5-O-Diferuloylquinic Acid And 3,5-(3,4-Dimethoxycinnamyl)Quinic Acid,In A Nine-Step Sequence. The Key Step Involves Knoevenagel Condensations Between Vanillin. 3,4-Dimethoxybenzaldehyde Or 4-Hydroxy-3-Methoxy-Benzaldehyde And The Dimalonate Ester Of Quinic Acid. Crown Copyright (C) 2011 Published By Elsevier Ltd. All Rights Reserved.
    Doi:10.1016/j.Tetlet.2011.10.127

    海关参考信息

    专利信息


    专利号:US-9339521-B2
    优先权日:2007-04-17
    标题:Use of vernonia extract
    发明人:SEGOND CAROLINE; LOISEAU ALAIN; PETIT VIRGINIE; THERON ERIC
    权利人:SEGOND CAROLINE; LOISEAU ALAIN; PETIT VIRGINIE; THERON ERIC; BAYER CONSUMER CARE AG
    摘要:The present invention relates to the use of an extract of a Vernonia plant from Madagascar in cosmetics, pharmaceuticals and food supplements for improving the skin status, more specifically by strengthening the dermal-epidermal junction and/or by activating fibroblasts synthesis of dermis and extracellular matrix compounds.

    专利号:EP-3174990-A1
    优先权日:2014-05-23
    标 题 :Method of synthesis of monocaffeoylquinic or dicaffeoylquinic acid

    专利号:CN-102796746-A
    优先权日:2012-08-07
    标题:A gene segment regulating the synthesis of Solanaceae flavonoids and caffeoylquinic acid and its application

    专利号:CN-102796746-B
    优先权日:2012-08-07
    标题 :Gene segment for regulating synthesis of solanaceae flavonoids and caffeoyl quinic acid, and uses thereof

    专利号:CN-114395566-B
    优先权日:2022-03-28
    标题:Application of sweet potato ERF transcription factor IbERF4 in promoting synthesis of plant chlorogenic acid substances

    专利号:JP-2009207492-A
    优先权日:2008-02-06
    标 题 :Enzymatic synthesis of cinnamic acid derivatives
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    合成参考文献


    参考文献:10.1016/s0026-895x(25)09385-x
    摘要:Robinson WE, Cordeiro M, Abdel-Malek S, Jia Q, Chow SA, Reinecke MG, Mitchell WM. Dicaffeoylquinic acid inhibitors of human immunodeficiency virus integrase: inhibition of the core catalytic domain of human immunodeficiency virus integrase. Molecular Pharmacology. 1996 Oct;50(4):846–55. doi: 10.1016/s0026-895x(25)09385-x.
    参考文献:10.1007/s10886-018-0958-9
    摘要:Mori S, Fukui H, Oishi M, Sakuma M, Kawakami M, Tsukioka J, Goto K, Hirai N. Biocommunication between Plants and Pollinating Insects through Fluorescence of Pollen and Anthers. Journal of Chemical Ecology. 2018 May 02;44(6):591–600. doi: 10.1007/s10886-018-0958-9.
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