CAS: 50638-46-5; 4-Bromo-3-Chloroanisole

上下游产品

CAS号13631-21-5 4-溴-3-氯苯酚 | CAS号74-88-4 碘甲烷 | CAS号2845-89-8 3-氯苯甲醚 | CAS号21402-26-6 4-溴-3-氯苯胺 | CAS号29682-39-1 1-溴-2-氯-4-硝基苯 | CAS号29866-52-2 3-bromo-2-chlor... | CAS号3260-88-6 2-氯-6-甲氧基甲苯 | CAS号29866-54-4 2-氯-6-甲氧基苯甲醛 | CAS号441060-95-3 2-(2-氯-4-甲氧基苯基)... | CAS号219735-99-6 2-氯-4-茴香醚硼酸

3-氯-2-甲基苯甲醚置于三氯化铝,溴体系中,化学反应生成 4-溴-3-氯苯甲醚
参考文献:Akermark,B.,Acta Chemica Scandinavica (1947),1970,Vol. 24,# 4,P. 1459-1460
标题:Akermark,B.,Acta Chemica Scandinavica (1947),1970,Vol. 24,# 4,P. 1459-1460

专利信息

专利号:US-7884125-B2
优先权日:2008-04-30
标 题:Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues
发明人：STEVENS CHRISTIAN; HEUGEBAERT THOMAS
权利人:UNIV GENT
摘要:The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

专利号:US-2009275616-A1
优先权日:2008-04-30
标 题 :Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues