CAS: 112-42-5; Undecan-1-Ol

该化合物是一种直链脂肪酒精,由11个碳原子组成;它是一种无色的粘液,在室温下具有粘性液体,具有典型的脂肪味;该化合物溶于乙醇和乙醚等有机溶剂,但因其长期的缺水碳链,在水中溶解性有限;1-Undecanol因其在生产表面活性剂,乳化剂和润滑剂时使用而闻名.它也可以作为一种调味剂,用于合成各种化学化合物.该物质与较短链酒精相比,沸点和熔点相对较高,反映其分子大小.此外,1-undecanol具有典型的原始酒精特性,包括能够进行氧化以形成甲酸和氨酸.安全数据表明,它应当谨慎处理,因为接触时可能会对皮肤和眼睛造成刺激.

结构式图片

相似化合物

112-44-7 1731-86-8 627-90-7

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号112-43-6 10-十一烯醇 | CAS号112-44-7 十一醛 | CAS号111-81-9 10-十一烯酸甲酯 | CAS号2834-05-1 11-溴十一酸 | CAS号830-13-7 环十二酮 | CAS号692-86-4 10-十一烯酸乙酯 | CAS号38841-98-4 辛基氯化镁 | CAS号627-18-9 3-溴-1-丙醇 | CAS号2050-77-3 1-碘癸烷 | CAS号201230-82-2 carbon monoxide | CAS号4282-44-4 碘十一烷 | CAS号3152-43-0 (3R,4R)-3,4-Dih... | CAS号364364-38-5 (2R,3R,4S,5R)-2... | CAS号43146-97-0 十一烷基醚 | CAS号2473-03-2 1-氯十一烷 | CAS号1731-86-8 十一酸甲酯 | CAS号52517-67-6 undecanal dimet... | CAS号20690-61-3 undecyl prop-2-... | CAS号54334-64-4 N,N-diethylunde... | CAS号121-44-8 三乙胺

合成工艺路线路线简述

  • 合成目标产物 1-Undecanol 主要起始原料 10-Undecen-1-Ol
  • (文献来源)合成步骤主要原料 10-Undecen-1-Ol
10-烯酸甲酯置于dichlorobis(2-(二苯基膦)乙胺)钌(II),Rucl2(Pph3)[(Etsc2H4)2Nh],氢气,Sodium Methylate,苯甲醚体系中,40.0 °C,500.01 Kpa 条件下,反应 72.0H,反应生成十一烷醇
参考文献:用钌催化剂选择性氢化不饱和酯和醛的可持续方法
标题:用钌催化剂选择性氢化不饱和酯和醛的可持续方法
摘要:温和条件下的选择性:比较了三种最先进的市售 Ru 催化剂在 40 oc 和 5 Bar 氢气条件下以苯甲醚用作溶剂选择性氢化含有 C=c 的酯和醛.
Doi:10.1002/cctc.202300394

海关参考信息

专利信息


专利号:US-7247752-B2
优先权日:2004-10-01
标 题 :Methods for the synthesis of astaxanthin
发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

专利号:US-10730904-B2
优先权日:2012-11-14
标 题:Method for liquid-phase synthesis of nucleic acid
发明人:NONOGAWA MITSURU; NAGATA TOSHIAKI; SAITO HIDEKI; YASUMA TSUNEO
权利人:TAKEDA PHARMACEUTICALS CO
摘要:In this method, an oligonucleotide represented by formula (II) [wherein Y 1 , Q, Base, r and r′ are each as defined in claim 1 ] is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R 1 , Y, Base, Z, Ar, R 2 , R 3 and n are each as defined in claim 1 ]. The novel nucleoside monomer compound is a nucleoside, the base moiety of which is substituted with an aromatic-hydrocarbon-ring-carbonyl or -thiocarbonyl group having at least one hydrophobic group. The method can dispense with column-chromatographic purification in every reaction, and enables base elongation not only in the 3′-direction but also in the 5′-direction, thus attaining efficient liquid-phase mass synthesis of an oligonucleotide.

专利号:US-7435861-B2
优先权日:2005-04-29
标 题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates
发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.

专利号:US-8642766-B2
优先权日:2008-05-05
标题 :Synthesis of (+) cortistatin A and related compounds
发明人:SHENVI RYAN A; GUERRERO CARLOS A; SHI JUN; LI CHUANG-CHUANG; BARAN PHIL S
权利人:SHENVI RYAN A; GUERRERO CARLOS A; SHI JUN; LI CHUANG-CHUANG; BARAN PHIL S
摘要:An in vitro synthesis of (+) cortistatin A from readily available precursors is disclosed, as are the syntheses of related 17-aryl substituted compounds, the 17-aryl substituted compounds themselves and novel compounds useful in their preparation.

专利号:US-2008221377-A1
优先权日:2006-06-16
标题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates
发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID; BRAUN CRISTI L
权利人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID; BRAUN CRISTI L
摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.

专利号:WO-9617589-A1
优先权日:1994-12-08
标 题 :Method of smoothing or removing wrinkles and method of stimulating collagen synthesis
发明人:FUJIMURA TSUTOMU; OGAWA AYUMI; OHSU HIROYUKI; TAKEMA YOSHINORI; HORI KIMIHIKO; AMANO SHINYA; FUJIMORI TAKETOSHI; OHASHI YUKIHIRO; SUZUKI YASUTO
权利人:KAO CORP; FUJIMURA TSUTOMU; OGAWA AYUMI; OHSU HIROYUKI; TAKEMA YOSHINORI; HORI KIMIHIKO; AMANO SHINYA; FUJIMORI TAKETOSHI; OHASHI YUKIHIRO; SUZUKI YASUTO
摘要:The present invention relates to methods of stimulating collagen synthesis and of smoothing or removing wrinkles, which comprise administering an effective amount of a benzoic acid derivative of formula (1) or a salt thereof, wherein X is -O- or -N(R4)- (R4 is H or the like), R1 is a C¿4-25?-alkyl or C4-25-alkenyl group, R?2¿ is H, OH, or a C¿1-6?-alkoxyl or C1-6-alkanoyloxy group, and R?3 is -OR5¿ or -N(R?6)R7 (R5? is H, or a C1-25-alkyl or C1-25-alkenyl group), and R?6 and R7¿ are individually H, or a C¿1-3?-alkyl or C1-3-alkenyl group, and use of this compound for agents for stimulating synthesis of collagen, and smoothing or removing wrinkles. This compound (1) stimulates collagen synthesis in human dermal fibroblasts and consequently smooths or removes wrinkles caused by aging and/or photoaging.
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主要参考文献

[参考文献]: Forney Fw, Et Al. Bacterial Oxidation Of 2-Tridecanone To 1-Undecanol. J Bacteriol. 1967 Feb;93(2):649-55.
[参考文献]: K Sharafi, Et Al. Trace Determination Of Lead In Lipsticks And Hair Dyes Using Microwave-Assisted Dispersive Liquid-Liquid Microextraction And Graphite Furnace Atomic Absorption Spectrometry. Int J Cosmet Sci. 2015 Oct;37(5):489-95.
[参考文献]: Kamyar Ahmadi, Et Al. Chemometric Assisted Ultrasound Leaching-Solid Phase Extraction Followed By Dispersive-Solidification Liquid-Liquid Microextraction For Determination Of Organophosphorus Pesticides In Soil Samples. Talanta. 2015 May:137:167-73.
[参考文献]: Ketsarin Seebunrueng, Et Al. Vortex-Assisted Low Density Solvent Liquid-Liquid Microextraction And Salt-Induced Demulsification Coupled To High Performance Liquid Chromatography For The Determination Of Five Organophosphorus Pesticide Residues In Fruits. Talanta. 2015 Jan:132:769-74.
[参考文献]: Kyle D Dukes, Et Al. Core-Shell Silver Nanoparticles For Optical Labeling Of Cells. Anal Biochem. 2014 Aug 1:458:43-8.

合成参考文献


参考文献:10.1007/s10886-010-9746-x
摘要:Dweck HKM, Svensson GP, Gündüz EA, Anderbrant O. Kairomonal Response of the Parasitoid, Bracon hebetor Say, to the Male-Produced Sex Pheromone of Its Host, the Greater Waxmoth, Galleria mellonella (L.). Journal of Chemical Ecology. 2010 Feb 16;36(2):171–8. doi: 10.1007/s10886-010-9746-x.
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