2,2-二甲基-1,3-苯并二恶茂烷置于硫酸,溴,乙酸酐体系中,化学反应生成4-溴邻苯二酚 参考文献:Slooff,Recueil Des Travaux Chimiques Des Pays-Bas,1935,Vol. 54,P. 995,999 标题:Slooff,Recueil Des Travaux Chimiques Des Pays-Bas,1935,Vol. 54,P. 995,999
专利号:US-9981887-B1 优先权日:2017-01-10 标题 :Synthesis of phenylethynylbenzenes 发明人:LASKOSKI MATTHEW; KELLER TEDDY M 权利人:US NAVY 摘要:A method of: reacting a dihydroxybenzene with bromine to form a bromodihydroxybenzene; reacting the bromodihydroxybenzene with trifluoromethanesulfonyl chloride or trifluoromethanesulfonic anhydride to form a bromotrifluoromethanesulfonatobenzene; and reacting the bromotrifluoromethanesulfonatobenzene with phenylacetylene to form a phenylethynylbenzene.
专利号:WO-2024220193-A1 优先权日:2023-04-21 标题 :Methods for preparing (-)-epicatechin 发明人:PAIS GODWIN 权利人:MARS INC 摘要:Methods steps for the synthesis of (-)-epicatechin are provided herein. The synthetic methods are provided in two phases: (1) synthesis of epoxide intermediates and (2) synthesis of (-)-epicatechin.
专利号:CN-119320374-A 优先权日:2024-11-04 标 题 :A method for photocatalytic synthesis of 3-sulfonyl-substituted chromone derivatives
专利号:WO-2007045420-A2 优先权日:2005-10-17 标题 :3-alkyl-5- (4-alkyl-5-oxo-tetrahydrofutran-2-yl) pyrrolidin-2-one derivatives as intermediates in the synthesis of renin inhibitors
专利号:US-9938258-B2 优先权日:2012-11-29 标 题:Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof 发明人:BALOGLU ERKAN; SHECHTER SHARON; SHACHAM SHARON; MCCAULEY DILARA; SENAPEDIS WILLIAM; GOLAN GALI; KALID ORI 权利人:KARYOPHARM THERAPEUTICS INC 摘要:The invention generally relates to substituted 2,3-dihydrobenzofuranyl compounds, and more particularly to a compound represented by Structural Formula I: n nor a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.
摘要:Inamoto, K., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 417. 摘要:Li, D.-D.; Wang, G.-W., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 355. 摘要:G. Ackermann, D. Hesse and P. Volland, Z. Anorg. Allg. Chem. 377, 92 (1970). 参考文献:10.1007/bf00114628 摘要:Marr J, Kremer S, Sterner O, Anke H. Transformation and mineralization of halophenols by Penicillium simplicissimum SK9117. Biodegradation. 1996 Apr;7(2):165–71. doi: 10.1007/bf00114628.