CAS: 362-76-5; 2-Amino-9-((3Ar,4R,6R,6Ar)-6-(Hydroxymethyl)-2,2-Dimethyltetrahydrofuro[3,4-D][1,3]Dioxol-4-yl)-1H-Purin-6(9H)-One

上下游产品

CAS号118-00-3 鸟苷 | CAS号67-64-1 丙酮 | CAS号77-76-9 2,2-二甲氧基丙烷 | CAS号25030-19-7 [2-(2-amino-6-o... | CAS号7803-88-5 6-O-甲基鸟苷 | CAS号118-00-3 鸟苷 | CAS号85-32-5 鸟苷酸 | CAS号146-91-8 鸟苷-5'-二磷酸 | CAS号14490-85-8 N-(guanin-8-yl)... | CAS号52417-04-6 [2-(2-amino-6-o...

2-(Ethoxymethyl-Amino)-9-((3Ar,4R,6R,6Ar)-6-Hydroxymethyl-2,2-Dimethyl-Tetrahydro-Furo[3,4-D][1,3]Dioxol-4-yl)-1,9-Dihydro-Purin-6-One置于sodium Hydroxide体系中,用 1,4-二氧六环 用作溶剂,化学反应 15.0H,反应生成2',3'-O-异丙亚基鸟苷
参考文献:核糖核苷衍生物与甲醛在乙醇溶液中的反应
标题:核糖核苷衍生物与甲醛在乙醇溶液中的反应
摘要:2',3'-O-异亚丙基-腺苷,-胞苷和-鸟苷,(2A),(3A)和(4A)分别与甲醛在乙醇溶液中反应,得到相应的n-乙氧基甲基衍生物,(2B),(3B)和(4B),分别具有非常好的产量.
Doi:10.1039/c39800000208

专利信息

专利号:US-8614312-B2
优先权日:2008-02-21
标 题 :Method for preparing nucleotides and related analogues by synthesis on soluble substrate, and biological tools thus prepared
发明人：PEYROTTES SUZANNE; PERIGAUD CHRISTIAN; CRAUSTE CELINE
权利人:PEYROTTES SUZANNE; PERIGAUD CHRISTIAN; CRAUSTE CELINE; CENTRE NAT RECH SCIENT; UNIV MONTPELLIER II
摘要:The invention concerns a method for preparing monomer nucleotides or nucleotide analogues comprising the steps of: (1) coupling a soluble polyethylene glycol support provided with at least one diacid or ether-acid linker and a monomer nucleoside or nucleoside analogue to an amine group or hydroxyl group of the nucleoside with the aid of a coupling agent; (2) at least one step for phosphorylation of said nucleoside or nucleoside analogue coupled to said support with a phosphorylation agent; (3) cleavage of said support and recovery of at least one monomer nucleotide or nucleotide analogue. The nucleotides prepared are biological tools.

专利号:FR-2927901-A1
优先权日:2008-02-21
标题 :PROCESS FOR THE PREPARATION OF NUCLEOTIDES AND ANALOGUES SUCH AS SYNTHESIS ON SOLUBLE CARRIER AND PREPARED BIOLOGICAL TOOLS