CAS: 6314-28-9; Benzo[b]Thiophene-2-Carboxylic Acid

上下游产品

CAS号7342-85-0 2-chlorobenzo[b... | CAS号201230-82-2 carbon monoxide | CAS号124-38-9 二氧化碳 | CAS号568572-21-4 苯并噻吩-2-硼酸新戊二醇酯 | CAS号95-15-8 苯并噻吩 | CAS号17890-56-1 1-苯并噻吩-2-甲醇 | CAS号67-56-1 甲醇 | CAS号22913-24-2 甲基苯并噻吩-2-甲醛 | CAS号89-98-5 邻氯苯甲醛 | CAS号68-11-1 硫代乙醇酸(TGA) | CAS号104795-66-6 3-ISOPROPOXY-5-... | CAS号3541-37-5 苯并[b]噻吩-2-甲醛 | CAS号39827-11-7 苯并[b]噻吩-2-甲酰氯 | CAS号112855-75-1 tetraethyl [(2-... | CAS号2076-88-2 2-(氯甲基)苯并[b]噻吩 | CAS号27916-82-1 2,3-dihydro-1-b... | CAS号95-15-8 苯并噻吩 | CAS号1014608-55-9 butyl (E)-3-(be... | CAS号29174-66-1 3-溴苯并噻吩-2-羧酸

3-Mercapto-2H-1-Benzopyran-2-One置于四丁基溴化铵,Potassium Hydroxide体系中,用 水 作为反应溶剂,135.0 °C,1.0 Mpa 条件下,反应 9.0H,以49.4%的收率获得产物苯并噻吩-2-羧酸
参考文献:苯并噻吩-2-羧酸的制备方法
标题:苯并噻吩-2-羧酸的制备方法
摘要:本发明公开了一种苯并噻吩‑2‑羧酸的制备方法,在高压容器内,以3‑巯基香豆素为原料,以四丁基溴化铵为催化剂于碱液中进行反应;先调节高压容器内的压力为0.8~1.2Mpa,然后加热至130~160oc反应7~10H;催化剂为原料的2~12.5Mol%,碱为原料的1.5~3.6摩尔倍;反应结束冷却至室温后加入浓盐酸酸化至反应产物ph=3~4,过滤干燥得苯并噻吩‑2‑羧酸.

专利信息

专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人：HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

专利号:EP-2918579-A1
优先权日:2014-03-14
标题 :Synthesis of 2-arylmethyl-5-aryl-thiophene
权利人:LEK PHARMACEUTICALS
摘要:The present invention provides a new synthetic process for the production of 2-arylmethyl-5-aryl-thiophene, an intermediate in the synthesis of C-aryl glycosides.

专利号:US-6372945-B1
优先权日:1995-06-07
标 题 :Process for the synthesis of vinyl sulfoxides
发明人：AIKINS JAMES A; MILLER RANDAL SCOT; ZHANG TONY Y
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfoxides, in particular diarylvinyl sulfoxides

专利号:US-5606076-A
优先权日:1995-06-07
标 题 :Process for the synthesis of benzo[b]thiophenes
发明人：AIKINS JAMES A; ZHANG TONY Y
权利人:LILLY CO ELI
摘要:The present invention is directed to a process for the synthesis of 2-arylbenzo[b]thiophenes.

专利号:US-5569772-A
优先权日:1995-06-07
标 题:Process for the synthesis of benzo[b]thiophenes
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of 2-aryl benzo[b]thiophenes, and to novel intermediates therefor.

专利号:US-5606075-A
优先权日:1995-06-07
标 题:Process for the synthesis of benzo[b]thiophenes
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to new processes for the synthesis of 2-aryl benzo[b]thiophenes.