专利号:US-2012168686-A1 优先权日:2009-09-03 标 题:Continuous Synthesis of Carbon-Coated Lithium-Iron-Phosphate 发明人:METZ HANS JOACHIM; WASER OLIVER; BUECHEL ROBERT; PRATSINIS SOTIRIS E 权利人:METZ HANS JOACHIM; WASER OLIVER; BUECHEL ROBERT; PRATSINIS SOTIRIS E; CLARIANT FINANCE BVI LTD 摘要:The invention relates to a continuous process for preparing carbon-coated lithium-iron-phosphate particles, wherein the carbon-coated lithium-iron-phosphate particles have a mean (d 50 ) particle size of 10 to 150 nm, and wherein the carbon-coating is an acetylene-black coating, comprising performing in a reactor a flame-spray pyrolysis step (i) in a particle formation zone of the reactor, and a carbon-coating step (ii) in a carbon-coating zone of the reactor, wherein inn (i) a combustible organic solution containing a mixture of lithium or a lithium compound; iron or an iron compound; and phosphorus or a phosphorous compound in an organic solvent, is fed through at least one nozzle where said organic solution is dispersed, ignited and combusted, to give a flame spray thereby forming an aerosol of lithium iron phosphate particles; (ii) acetylene gas is injected into said aerosol thereby forming an acetylene-black coating on the lithium iron phosphate particles; (iii) the coated particles are cooled by an inert quench gas and collected on a filter.
专利号:EP-1686129-A1 优先权日:2004-08-18 标题:Carbapenems, their preparation and use the synthesis of carbapenems 发明人:ALBERT MARTIN; KREMMINGER PETER; SILBERBERGER HERBERT 权利人:SANDOZ AG 摘要:Pyrrolidine compound (V), in free or salt form, is new. Pyrrolidine compound of formula (V), in free or salt form, is new. Independent claims aren also included for: (1) the preparation of (V); (2) the preparation of 3-[(3S,5S)-5-carbamido-3-pyrrolidinyl]-thio substituted carbapenem compound of formula (II) comprising reaction of (V) with an amine compound of formula (NH(R1)(R2)) to give a pyrrolidine compound of formula (III); and elimination of p-nitrobenzyl- and/or p-nitrobenzylcarbonyl-protection groups from (III); and (3) preparation of a pharmaceutical composition of (II) comprising mixing (II) with solvents or auxiliary materials. Either R1, R2alkyl, H, aryl or heterocyclyl; or NR1R25-8 membered optionally saturated heterocyclic group (optionally substituted). [Image] [Image].
专利号:EP-2292557-A1 优先权日:2009-09-03 标题 :Continuous synthesis of carbon-coated lithium-iron-phosphate
专利号:US-2025034074-A1 优先权日:2021-11-25 标题:Process for preparing a cyclic diene 发明人:JACOBY DENIS; CHAPPUIS SIMONE; KELLER FABRICE 权利人:FIRMENICH & CIE 摘要:The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I) comprising the reaction of a compound of the formula (II) with a base having a boiling point superior to the boiling point of the compound of formula (I). Moreover, the compound of formula (I) and the compound of formula (II) are also part of the invention.