CAS: 47339-09-3; 2,3,4,6-Tetra-O-Acetyl-D-Galactopyranose

该化合物是D-galactopyranose的衍生物,一种六人环状甘蔗甘蔗甘蔗甘蓝的六种环状体,其特征是,在2,3,4和6号方位,有四个乙酰组附于羟基组,其位置为2,3,4和6;乙酰胺强化分子的亲脂性,可影响其溶解性和再活性;D-甘二甲酚本身是单色素,是各种多色素和甘油蛋白的重要成分;四氧基体形态经常用于生物化学研究和合成,特别是在涉及碳水化合物化学和酶反应的研究中;其结构允许与酶和感应器进行特定互动,使其成为碳水化合物新陈代谢和识别研究中的宝贵化合物.此外,该化合物的稳定性和再活性可能受原糖组存在的影响,这种原状组在某种原状条件下可以成为水体.

结构式图片

相似化合物

22415-91-4 83-87-4 10343-06-3

上下游产品

2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl chloride acetobromomannose D-Mannose pentaacetate D-Mannose 3,4,6-tri-O-acetyl-1,2-O-(1-ethoxyethylidene)-β-D-mannopyranoside 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl bromide 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl fluoride 2,3,4,6-tetra-O-acetyl-β-D-mannopyranosyl fluoride

合成工艺路线路线简述

    Beta-D-半乳糖五乙酸酯置于乙酸肼体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应 0.33H,以80%的收率获得产物2,3,4,6-O-四乙酰基-D-半乳糖
    参考文献:十种典型的角叉菜胶低聚糖的合成策略-保护性γ-角叉菜胶四糖的合成
    标题:十种典型的角叉菜胶低聚糖的合成策略-保护性γ-角叉菜胶四糖的合成
    摘要:提出了一种化学合成所有十种典型角叉菜胶低聚糖的策略.组装中心的,受保护的四糖,并举例说明进一步的保护基操纵和硫酸化.
    DOI:10.1002/ejoc.201900592

    海关参考信息

    专利信息


    专利号:US-6229055-B1
    优先权日:1996-04-12
    标题 :Synthesis of fluorinated xanthene derivatives
    发明人:KLAUBERT DIETER H; GEE KYLE R
    权利人:MOLECULAR PROBES INC
    摘要:Facile syntheses for fluorinated resorcinol and aminophenol derivatives are provided that yield isomer-free products in good yield. These novel methods use generally available precursors and standard laboratory reagents and equipment to reproducibly produce these synthetically useful reagents in relatively large quantities. The resulting fluorinated resorcinols and aniinophenols possess utility in the preparation of fluorinated fluorescein and rhodol dyes.

    专利号:WO-9840512-A2
    优先权日:1997-03-13
    标 题 :Transglycolytic synthesis of branched oligosaccharides

    专利号:EP-0968301-A2
    优先权日:1997-03-13
    标题:Transglycolytic synthesis of branched oligosaccharides

    专利号:US-5756712-A
    优先权日:1997-01-23
    标题:Peptidodisaccharides as oligosaccharide mimetics
    发明人:SABESAN SUBRAMANIAM
    权利人:DU PONT
    摘要:Methods are provided to replace the ether oxygen linkage of oligosaccharides with a peptide link, -NHC(O)-, where the nitrogen atom is linked to the anomeric carbon atom of the sugar. A new family of building blocks for combinational synthesis, peptidodisaccharides, is provided containing the peptide linkage. Synthesis is more facile than with the oxygen-linked carbohydrates; the resulting compounds are expected to be more stable to enzymatic and chemical hydrolysis and to be amenable to automated synthesis.

    专利号:WO-0004007-A1
    优先权日:1998-07-17
    标 题 :Fluorescent dibenzazole derivatives and methods related thereto
    发明人:BROWN LAUREN R; XU CHENG
    权利人:PROMEGA BIOSCIENCES INC
    摘要:Dibenzazole compounds having general structure (I and II), wherein: R1, R2, R3, R4, R5, R6 are independently H or a substituent which aids in solubility of the compound or which provides a linker arm for linking the compound to another moiety; Y is H or a cleavable moiety; X is a hydrogen, halogen, CF3, or SO3H; V and W are oxygen or sulfur; Z is -C=C-, -C C- or an aromatic ring moiety; and n is 0, 1, or 2. When n=0 at least one of R1, R2, R3, R4, and R5 is a substituent which aids in solubility of the compound or which provides a linker arm for linking the compound to another moiety or X is a halogen, CF3 or SO3H. These compounds are highly fluorescent and can be easily detected using a fluorometer. Derivatives in which the Y group is a substituent other than H contain a fluorescence inhibiting chemical moiety that upon removal restores the fluorescence of the compound. Methods for their synthesis and application are provided.

    专利号:US-6140051-A
    优先权日:1997-07-21
    标 题:Fluorescent dibenzazole derivatives and methods related thereto
    发明人:BROWN LAUREN R; XU CHENG
    权利人:PROMEGA BIOSCIENCES INC
    摘要:Dibenzazole compounds having the general structure: wherein; R1, R2, R3, R4, R5, R6 are independently H or a substituent which aids in solubility of the compound or which provides a linker arm for linking the compound to another moiety; Y is H or a cleavable moiety; X is a hydrogen, halogen, CF3, or SO3H; V and W are oxygen or sulfur; Z is -C=C-, -C 3BOND C- or an aromatic ring moiety; and n is 0, 1, or 2. When n=0 at least one of R1, R2, R3, R4, and R5 is a substituent which aids in solubility of the compound or which provides a linker arm for linking the compound to another moiety or X is a halogen, CF3 or SO3H. These compounds are highly fluorescent and can be easily detected using a fluorometer. Derivatives in which the Y group is a substituent other than H contain a fluorescence inhibiting chemical moiety that upon removal restores the fluorescence of the compound. Methods for their synthesis and application are provided.
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    主要参考文献

    参考标题:Streptococcus Pneumoniae Type Xiv Polysaccharide: Synthesis Of A Repeating Branched Tetrasaccharide With Dioxa-Type Spacer-Arms
    作者:Paul-Henri Amvam-Zollo,Pierre Sinaÿ |发布日期:1986.8
    摘要:Beta-Glycosides Of 2-Acetamido-2-Deoxy-D-Glucopyranose Were Synthesised, Using Either 7-Methoxycarbonyl-3,6-Dioxa-1-Heptanol Or 8-Azido-3,6-Dioxa-1-Octanol. Selective Beta-Lactosylation Of 7-Methoxycarbonyl-3,6-Dioxaheptyl 2-Acetamido-3-O-Benzyl-2-Deoxy-Beta-D-Glucopyranoside With Hepta-O-Acetyl-Lactosyl-Trichloroacetimidate, Followed By Beta-Galactosylation Of The Secondary Hydroxyl Group With O-(2

    合成参考文献


    摘要:Kryczka, B.; Lewkowski, J.; Zawisza, A., Science of Synthesis, (2007) 29, 992.
    摘要:Kryczka, B.; Lewkowski, J.; Zawisza, A., Science of Synthesis, (2007) 29, 1027.
    摘要:Robina, I.; Vogel, P., Science of Synthesis, (2008) 37, 800.
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