782452-40-8 = 530-57-4 + 884-35-5 反应条件:1.1 Reagents: Ethylene Glycol Solvents: Ethylene Glycol; 1 H,120 °C 标题:Simple Deprotection Of Acetal Type Protecting Groups Under Neutral Conditions 作者:Miyake,Hideyoshi; Et Al 参考文献:Tetrahedron Letters 日期:2004 卷标:45(39) 页码:7213-7215
3,5-二溴-4-羟基苯甲酸置于sodium Methylate,Sodium,碘化亚铜体系中,用 N-甲基乙酰胺,甲醇 作为反应溶剂,化学反应生成 丁香酸 参考文献:Process For Preparing Pyrogallol 标题:Process For Preparing Pyrogallol 摘要:白脲酚是通过以下步骤制备的:(A)将化学式为##str1##的卤代化合物与化学式为rom的碱金属烷氧化物反应,其中x代表br或i,R.Sup.1代表氢,长达10个碳原子的二级或三级烷基,2-5个碳原子的羧基或烷氧羰基,R.Sup.2代表氢或1-4个碳原子的烷基,以替换每个x为or;然后(B)脱烷基化每个or和每个or.Sup.2,其中r.Sup.2代表1-4个碳原子的烷基,并去除r.Sup.1基团,如果r.Sup.1不是氢的话.
专利号:US-8647848-B2 优先权日:2008-06-13 标题:Enzymatic synthesis of sphingolipids 发明人:HOLLMANN FRANK; THUM OLIVER; TOELLE CHRISTOPH; PROVINZANO ANGELO; KOREVAAR CORNELIS GERRIT NIJS 权利人:HOLLMANN FRANK; THUM OLIVER; TOELLE CHRISTOPH; PROVINZANO ANGELO; KOREVAAR CORNELIS GERRIT NIJS; EVONIK GOLDSCHMIDT GMBH 摘要:The invention relates to the enzymatic synthesis of sphingolipids and compositions that contain sphingolipids from lysosphingolipids and carbonic esters, and to cosmetic, dermatological or pharmaceutical formulations containing said sphingolipids or compositions.
专利号:US-2006052577-A1 优先权日:2001-02-06 标题:Methods of synthesis of polymers and copolymers from natural products 发明人:SWIFT GRAHAM; WESTMORELAND DAVID G; HUGHES KATHLEEN 权利人:SWIFT GRAHAM; WESTMORELAND DAVID G; HUGHES KATHLEEN 摘要:Described are polymers and copolymers containing sorbitol, citric acid, starch, aspartic acid, succinic anhydride, adipic acid mixtures thereof, methods of their synthesis and their uses.
专利号:US-6180830-B1 优先权日:1995-11-08 标题 :Method for preparing a bimetallic ruthenium/tin catalyst and a process for the synthesis of aldehydes 发明人:JACQUOT ROLAND 权利人:RHODIA CHIMIE SA 摘要:The present invention relates to a new process for the preparation of a bimetallic ruthenium/tin catalyst. The process for the preparation of a bimetallic ruthenium/tin catalyst according to the invention is characterised by the fact that it consists in carrying out the reduction of a ruthenium complex having an electrovalency of -4 and a coordination number of 6, the ligands being either a halogen atom or an anion or a tin halide. The catalyst is further employed for the preparation of aldehydes by reduction, in the vapor phase, of carboxylic acids, esters and anhydrides.
专利号:US-2004110228-A1 优先权日:2002-04-01 标 题:Combinatorial organic synthesis of unique biologically active compounds 发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M 摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.
专利号:US-9453037-B2 优先权日:2011-07-28 标 题 :Methylphenidate-prodrugs, processes of making and using the same 发明人:GUENTHER SVEN; CHI GUOCHEN; BERA BINDU; MICKLE TRAVIS; BERA SANJIB 权利人:KEMPHARM INC; KEMPHARM INC 摘要:The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.
专利号:US-6600001-B1 优先权日:2002-01-11 标 题:Alkylamino oxamides as low odor, non-fugitive catalysts for the production of polyurethanes 发明人:GERKIN RICHARD M; ROBINSON KARENA KAYE; DERERIAN EDMOND J 权利人:CROMPTON CORP 摘要:A process for the synthesis of polyurethanes is disclosed wherein the process comprises reacting polyurethane-forming reactants in the presence of an effective amount of a catalyst comprising at least one alkylamino oxainide of the structure:wherein:R1 and R2 are independently selected alkyl groups or can be taken together to form a five or six-membered heterocyclic ring;R3 and R4 are independently selected from the group consisting of hydrogen and alkyl;n is 2 or 3;x is 0 or 1;Y is selected from the group consisting of O and NR9, wherein:R9 is selected from the group consisting of hydrogen and alkyl; andX is selected from the group consisting of OR10 and G, wherein:R10 is selected from the group consisting of hydrogen and alkyl; andG is
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合成参考文献
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