CAS: 7664-66-6; 4-Isopropoxyaniline

该化合物是4-(1-甲基乙氧)苯丙胺.氢氧化铵是水中氨的一种溶液,其特征是碱性强,光味强,具有清洁剂和各种化学合成前体的能力.它通常用于家庭清洁剂和工业用途.另一方面,4-(1-甲基乙氧)苯胺,也称为替代阿线,通常具有无色的黄色液体或固态,在染料制造,制药或有机合成中具有潜在用途.其具体特性取决于其分子结构,包括溶性,沸点和再活性,这些结构受到甲基氧组和苯功能组的存在的影响.关于4-(1-甲基乙氧基苯基)苯胺的准确信息,请参考可靠的化学数据库或文献.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

1-isopropoxy-4-nitrobenzene N-(4-isopropoxyphenyl)acetamide N-(4-hydroxyphenyl)formamide isopropyl bromide thioisonicotinic acid-(4-isopropoxy-anilide) N-(2-isopropoxy-phenyl)-N'-(4-isopropoxy-phenyl)-acetamidineN-(2-isopropoxy-phenyl)-N'-(4-isopropoxy-phenyl)-acetamidine N-(4-isopropoxyphenyl)acetamide N-Chloracetyl-4-isopropyloxy-anilin

合成工艺路线路线简述

    O-异丙基乙酰氨基苯置于硫酸体系中,化学反应生成 对异丙氧基苯胺
    参考文献:überlokalanästhetischwirksame取代基二乙烯基氨基酰基苯胺衍生物
    标题:überlokalanästhetischwirksame取代基二乙烯基氨基酰基苯胺衍生物
    摘要:Es Wurden Verschiedene同系物reihen Vonxylocain-ähnlichenlokalanästhetikahergestellt和auf I Pharmakologischen Wirkungen Untersucht.乙二氨基氨基-乙酰氨基苯酚-烷基醚和二乙氨基-乙酰氨基-甲苯基-烷基醚的合成和wirkung的二元氨基-乙酰氨基-乙酰氨基-苯酚烷基酯和wirkung的二氨基氨基-乙酰氨基-乙酰氨基酚烷基酯.在对苯二甲酰二乙酰氨基乙酰氨基苯酚烷基酚的合成中使用了甲基丙烯酸丁酯(einfluss Dereinführungvoneinführungvon Methylgruppen).dabei Konnte Beim二氨基氨基乙酰氨基-二甲苯醇-烷基酯,D Kombination Der Strukturen Des Xylocains和des Pacetacetins,Eine
    DOI:10.1002/hlca.19510340131

    海关参考信息

    专利信息


    专利号:US-2015133460-A1
    优先权日:2013-11-11
    标题:Lactate salt of 4-[6-methoxy-7-(3-piperidin-1-yl-propoxy)quinazolin-4-yl]piperazine-1-carboxylic acid(4-isopropoxyphenyl)-amide and pharmaceutical compositions thereof for the treatment of cancer and other diseases or disorders
    发明人:ARMITAGE Ian; FERDOUS ABU J; BOURLAND MICHAEL E; BOYLE CRAIG S J; COOPER MARTIN IAN; LANGSTON MARIANNE
    权利人:MILLENNIUM PHAMACEUTICALS INC
    摘要:This invention provides a compound of formula (I): n n n n n n n n n n n n or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof; processes for the synthesis or manufacture of the compound of formula (I), or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof; and the use of said compound, or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof, for the treatment of patients suffering from or subject to diseases, disorders or conditions involving cell survival, proliferation, and migration, including cardiovascular disease (e.g., arteriosclerosis and vascular reobstruction), cancer, (e.g., AML and malignant glioma) glomerulosclerosis, fibrotic disease and inflammation.

    专利号:US-2010273808-A1
    优先权日:2008-11-21
    标 题 :Lactate salt of 4-[6-methoxy-7-(3-piperidin-1-yl-propoxy)quinazolin-4-yl]piperazine-1-carboxylic acid(4-isopropoxyphenyl)-amide and pharmaceutical compositions thereof for the treatment of cancer and other diseases or disorders
    发明人:ARMITAGE Ian; BOURLAND MICHAEL E; BOYLE CRAIG J S; COOPER MARTIN IAN; FERDOUS ABU J; LANGSTON MARIANNE
    权利人:MILLENNIUM PHARMACETICALS INC
    摘要:This invention provides a compound of formula (I): n n n n n n n n n n or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof; processes for the synthesis or manufacture of the compound of formula (I), or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof; and the use of said compound, or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof, for the treatment of patients suffering from or subject to diseases, disorders or conditions involving cell survival, proliferation, and migration, including cardiovascular disease (e.g., arteriosclerosis and vascular reobstruction), cancer, (e.g., AML and malignant glioma)glomerulosclerosis, fibrotic disease and inflammation.

    专利号:US-4874771-A
    优先权日:1988-09-06
    标 题 :Ethanesulfonamide derivatives
    发明人:RUSSELL RONALD K
    权利人:ORTHO PHARMA CORP
    摘要:The synthesis of novel ethanesulfonamide compounds is described. The novel ethanesulfonamide compounds have antisecretory activity and are used in the treatment of peptic ulcer disease.

    专利号:US-11229711-B2
    优先权日:2013-06-06
    标 题:Linkers for antibody-drug conjugates and related compounds, compositions, and methods of use
    发明人:JACKSON DAVID Y; HA EDWARD
    权利人:MAGENTA THERAPEUTICS INC
    摘要:Provided herein are antibody-cytotoxin antibody-drug conjugates and related compounds, such as linker-cytotoxin conjugates and the linkers used to make them, and intermediates in their synthesis; compositions; and methods, including methods of treating cancers.

    专利号:US-5112866-A
    优先权日:1988-09-06
    标题:Ethanesulfonamide derivatives
    发明人:RUSSELL RONALD K
    权利人:ORTHO PHARMA CORP
    摘要:The synthesis of novel ethanesulfonamide compounds is described. The novel ethanesulfonamide compounds have antisecretory activity and are used in the treatment of peptic ulcer disease. The intermediates used to prepare the ethanesulfonamides are useful in the treatment of osteoporosis and other bone wasting diseases.

    专利号:US-2007112150-A1
    优先权日:2005-07-21
    标题 :Diimine metal complexes, methods of synthesis, and method of using in oligomerization and polymerization
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    合成参考文献


    参考文献:10.4061/2011/162452
    摘要:Kuzuya A, Tanaka K, Komiyama M. Photoswitching of site-selective RNA scission by sequential incorporation of azobenzene and acridine residues in a DNA oligomer. J Nucleic Acids. 2011;2011():162452.
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