CAS: 31599-61-8; 4-Iodo-1,2-Dimethylbenzene

上下游产品

CAS号95-47-6 邻二甲苯 | CAS号7553-56-2 碘 | CAS号7697-37-2 硝酸 | CAS号64-19-7 冰醋酸 | CAS号4920-95-0 3,3',4,4'-四甲基联苯 | CAS号2026-27-9 1,1'-Biphenyl,3... | CAS号106053-01-4 3,4-dimethoxy-3... | CAS号5006-39-3 1-(3,4-dimethyl... | CAS号106053-06-9 4',5'-dimethoxy... | CAS号106053-07-0 4',4'',5',5''-t... | CAS号5973-71-7 3,4-二甲基苯甲醛 | CAS号2828-65-1 1,2-Dimethyl-4-... | CAS号28361-44-6 1,2-二甲基-4-甲苯磺酰苯 | CAS号78164-31-5 3,4-二甲基三氟甲苯

邻二甲苯置于dipotassium Peroxodisulfate,氯化胆碱,碘体系中,用 乙腈 用作溶剂,化学反应 3.5H,以69%的收率获得3,4-二甲基碘苯
参考文献:A Simple And Efficient Iodination Of Aromatic Compounds Using I2/choline Chloride/k2S2O8
标题:A Simple And Efficient Iodination Of Aromatic Compounds Using I2/choline Chloride/k2S2O8
摘要:在存在分子碘,氯化胆碱和过氧二硫酸钾的情况下,已在65oc的乙腈中实现了一种简单而高效的芳香化合物碘化方法.原位生成的胆碱过氧二硫酸盐促进了芳香化合物转化为碘芳香化合物的速率.该方案提供了一种高效合成碘芳烃的途径,操作简便,对功能集团具有非常好的耐受性,产率中等到非常好.
Doi:10.14233/ajchem.2018.21308

专利信息

专利号:WO-2015131100-A1
优先权日:2014-02-28
标题:Ligand-controlled c(sp3)-h arylation and olefination in synthesis of unnatural chiral alpha amino acids
发明人：YU JIN-QUAN
权利人:SCRIPPS RESEARCH INST
摘要:The use of ligands to tune the reactivity and selectivity of transition metal-catalysts for C(-sp3)-H bond functionalization is a central challenge in synthetic organic chemistry. Herein, we report a rare example of catalyst-controlled C(sp3)-H arylation using pyridine and quinoline derivatives: the former promotes exclusive monoarylation, whereas the latter activates the catalyst further to achieve diarylation. Successive application of these ligands enables the sequential diarylation of a methyl group in an alanine derivative with two different aryl iodides, affording a wide range of β-Ar-p-Ar ' -cc-amino acids with excellent levels of diastereoselectivity (d.r. > 20:1). Both configurations of the β-chiral center can be accessed by choosing the order in which the aryl groups are installed. The use of a quinoline derivative as a ligand also enables C(sp3)-H olefination of a protected alanine.

专利号:CN-107954908-B
优先权日:2017-12-10
标 题:Under a kind of microwave radiation in water phase benzene thiocarbamide catalytic synthesis of diaryl thioether method

专利号:CN-107954908-A
优先权日:2017-12-10
标题:A kind of method that phenylthiourea catalyzes the synthesis of diaryl sulfide in aqueous phase under microwave radiation

专利号:CN-111978139-A
优先权日:2020-09-04
标 题 :A kind of method for photocatalytic one-pot synthesis of phenol or its derivative in water phase

专利号:US-7169955-B2
优先权日:2000-02-04
标 题 :Perfluoroisopropylbenzene derivative
发明人：ONISHI MASANOBU; IKEDA KENICHI; SHIMAOKA TAKASHI; YOSHIDA MASANORI
权利人:NIHON NOHYAKU CO LTD
摘要:Perfluoroisopropylbenzene derivatives of the general formula (I) or salts thereof, useful as intermediates or raw materials in the synthesis of various industrial materials including agricultural chemicals, drugs and surfactants: n nwherein X 1 is H, halogen, formyl, optionally halogenated (C 1 –C 6 ) alkyl, (C 1 –C 6 ) alkylthio, or the like; X 2 is H, halogen, formyl, hydroxyl, (C 1 –C 6 ) alkyl, —C(â•?O)—R 1 (wherein R 1 is H, halogen, hydroxyl, (C 1 –C 6 ) alkyl, or NR 2 R 3 , with R 2 and R 3 being each H, C 1-6 alkyl, or the like), or the like; X 3 is H, halogen, hydroxyl, cyano, isocyanate, hydrazino, diazo, —C(â•?O)—R 1 , —SO 2 —R 4 (wherein R 4 is halogen, hydroxyl, (C 1 –C 6 ) alkyl, or NR 5 R 6 , with R 5 and R 6 being each H or (C 1 –C 6 ) alkyl), or the like; and X 4 is H, halogen, (C 1 –C 6 ) alkyl, or (C 1 –C 6 ) alkoxy, with publicly known compounds beingexcepted.

专利号:CN-106588788-B
优先权日:2016-11-11
标 题 :The method of one pot of two-step method synthesis 1,2,3- triazole compound