CAS: 127-66-2; 2-Phenylbut-3-Yn-2-Ol

相似化合物

6712-32-9 159028-51-0 74207-58-2

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CAS号98-86-2 苯乙酮 | CAS号4301-14-8 乙炔基溴化镁 | CAS号74-86-2 乙炔 | CAS号54655-07-1 三甲基硅烷基乙炔锂 | CAS号1066-26-8 乙炔化钠,二甲苯溶液 | CAS号75-20-7 电石 | CAS号6289-26-5 3-Hexyne-2,5-di... | CAS号1111-63-3 Potassium acetylide | CAS号20921-41-9 2-phenylbut-3-y... | CAS号2404-87-7 3-苯基噻吩 | CAS号1565-75-9 2-苯基-2-丁醇 | CAS号6051-52-1 3-Phenyl-1-bute... | CAS号3155-01-9 2-Butanone,3-hy... | CAS号95323-23-2 4-methyl-5-meth... | CAS号26274-35-1 2,4-二苯基吡啶 | CAS号98-83-9 α-甲基苯乙烯 | CAS号1187828-99-4 benzoic acid 1-... | CAS号217185-22-3 2-prop-2-enoxyb...

2-苯基-4-(三甲基甲硅烷基)-3-丁炔-2-醇置于potassium Carbonate体系中,用 甲醇 用作溶剂,化学反应 1.0H,反应生成2-苯基-3-丁炔-2-醇
参考文献:邻羰基辅助的丙炔基羧酸盐的氧乙酰氧基化在无金属条件下保持手性
标题:邻羰基辅助的丙炔基羧酸盐的氧乙酰氧基化在无金属条件下保持手性
摘要:提出了保留手性的伯,仲和叔炔丙基羧酸的无金属氧乙酰氧基化方法.该反应通过烷基炔酮中间体上相邻羰基的分子内亲核攻击而进行.该方法是一般的,具有广泛的底物范围,并且适用于包括从天然产物获得的那些炔丙基羧酸酯.通过同位素标记(使用h 2 O 18和d 2 O)洞察机械途径,并确认了对照实验.
Doi:10.1002/adsc.201900314

专利信息

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-5637757-A
优先权日:1995-04-11
标 题 :One-pot synthesis of ring-brominated benzoate compounds
发明人：HILL JOHN E; FAVSTRITSKY NICOLAI A; MAMUZIC RASTKO I; BHATTACHARYA BHABATOSH
权利人:GREAT LAKES CHEMICAL CORP
摘要:A method of preparing tetrabromobenzoate compounds from tetrabromophthalic anhydride by reacting tetrabromophthalic anhydride with alcohol in the presence of a decarboxylation catalyst. The reaction may be carried out in an excess of alcohol, or with a near stoichiometric amount of alcohol by performing the reaction in an inert solvent.

专利号:US-2003082830-A1
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

专利号:US-9981923-B2
优先权日:2014-06-20
标 题:1,2,3 Triazole antifungal agents and preparation thereof
发明人：CHEPURI VENKATA RAMANA; DESHPANDE MUKUND VINAYAK; TUPE SANTOSH GENBA; KOMMAGALA YADAGIRI
权利人:COUNCIL SCIENT IND RES
摘要:The present application relates to 1,4-disubstituted 1,2,3-Triazole antifungal agents of the formula (I) wherein, R1 is halogens such as fluorine, chlorine or bromine, CF3, alkyl; R2 is alkyl or hydrogen; R3 is halogen selected from fluorine, chlorine or bromine; and n is 0 or 1. The application further relates to the synthesis of said compounds, to fungicidal compositions containing said compounds and to their use in a method for treating fungal infections.

专利号:WO-0006525-A9
优先权日:1998-07-25
标题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

专利号:WO-0006525-A2
优先权日:1998-07-25
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products