CAS: 14064-10-9; Diethyl 2-Chloromalonate

相似化合物

36437-19-1 609-15-4 28868-76-0

上下游产品

2,2-二氯丙二酸二乙酯 Diethyl Dichloromalonate 20165-81-5
Diethyl Bromochloromalonate 81289-78-3
丙二酸二乙酯 Diethyl Malonate 105-53-3

丙二酸二乙酯置于正丁基锂,二异丙胺,氯磺酸甲酯体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应 1.0H,反应生成氯代丙二酸二乙酯
参考文献:在碱性条件下,使用氯硫酸甲酯对含羰基的化合物进行有效的α-氯化
标题:在碱性条件下,使用氯硫酸甲酯对含羰基的化合物进行有效的α-氯化
摘要:描述了一种使用碱性氯硫酸甲酯在碱性条件下α-氯化酮的有效方法.还研究了其对其他官能团氯化的适用性,并且对于合成α-氯酸酯和酰胺同样有用.氯硫酸甲酯首次被描述为正氯源.还报道了在某些底物的氯化过程中发生的一些羟醛反应.
Doi:10.1016/j.Tetlet.2018.02.036

专利信息

专利号:US-10294196-B2
优先权日:2015-11-18
标题:Process for the synthesis of intermediates useful for preparing 1,3,4-triazine derivatives
发明人：XU SHENG; XU YIHUI
权利人:FMC CORP
摘要:A process for the synthesis of 1,3-diethyl 2-(2-methylhydrazinylidene)propanedioate comprising the step of: reacting 2-halosubstituted diethyl malonate or mixtures of 2-halo-substituted diethyl malonates with methylhydrazine or the salt thereof in the presence of an acid catalyst is disclosed. 1,3-diethyl 2-(2-methylhydrazinylidene)propanedioate is an intermediate useful for preparing 1,3,4-triazines.

专利号:US-5981748-A
优先权日:1995-06-07
标题:Synthesis of optically pure compounds useful as GARFT inhibitors and their intermediates
发明人：VARNEY MICHAEL D; ROMINES WILLIAM H; PALMER CYNTHIA L
权利人:AGOURON PHARMA
摘要:The invention relates to methods of making compounds of the formula VII ##STR1## and their enantiomers, where Ar is a substituted or unsubstituted five- or six-membered aromatic group and B is either an amino acid linked through the amino portion to form an amide or a C 1 -C 6 alcohol linked through the alcohol portion to form an ester. These compounds are advantageously employed as intermediates to prepare optically pure compounds that are active GARFT inhibitors. In one method, a compound of the formula ##STR2## is reacted with a compound of the formula ##STR3## where X is a halogen.

专利号:US-6153705-A
优先权日:1997-06-23
标题 :Method for block polymer synthesis by controlled radical polymerisation
发明人：CORPART PASCALE; CHARMOT DOMINIQUE; ZARD SAMIR Z; BIADATTI THIBAUD; MICHELET DANIEL
权利人:RHODIA CHIMIE SA
摘要:PCT No. PCT/FR98/01316 Sec. 371 Date Jan. 14, 1999 Sec. 102(e) Date Jan. 14, 1999 PCT Filed Jun. 23, 1998 PCT Pub. No. WO98/58974 PCT Pub. Date Dec. 30, 1998The invention relates to a process for polymerizing block polymers of general formula (I): in which process the following are brought into contact with each other: an ethylenically unsaturated monomer of formula: CYY'(=CW-CW')a=CH2, a precursor compoun of general formula (II): a radical polymerization initiator.

专利号:US-2018334427-A1
优先权日:2015-11-18
标 题 :Process for the Synthesis of Intermediates Useful for Preparing 1,3,4-Triazine Derivatives

专利号:US-6545098-B1
优先权日:1997-12-31
标 题:Synthesis method for block polymers by controlled radical polymerization from dithioester compounds
发明人：BOUHADIR GHENWA; CHARMOT DOMINIQUE; CORPART PASCALE; ZARD SAMIR
权利人:RHODIA CHIMIE SA
摘要:The invention concerns a method for preparing, by radical polymerisation, block polymers of general formula (1), which consists in contacting: an ethylenically unsaturated monomer of formula CYY'(=CW-CW')a=CH2: and a precursor compound of general formula (II): a radical polymerization initiator.

专利号:ES-2206580-T3
优先权日:1995-06-07
标题 :SYNTHESIS OF OPTICALLY PURE COMPOUNDS USEFUL AS INJERTS OF INJERTO AND ITS INTERMEDIARIES.