CAS: 149597-91-1; (R)-2-Amino-3,3-Diphenylpropanoic Acid

相似化合物

149597-92-2 138662-63-2 143060-31-5

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CAS号177583-36-7 methyl 2-(tert-... | CAS号62653-26-3 2-氨基-3,3-二苯丙酸 | CAS号90-99-3 二苯基氯甲烷

2-氨基-3,3-二苯丙酸置于硫酸体系中,用 甲醇,水 用作溶剂,化学反应生成L-3,3-二苯基丙氨酸,D-3,3-二苯基丙氨酸
参考文献:(18-Crown-6)-四羧酸作为手性冠醚选择剂对 α-氨基酸及其酯的对映异构体分离度的核磁共振和高效液相色谱比较研究
标题:(18-Crown-6)-四羧酸作为手性冠醚选择剂对 α-氨基酸及其酯的对映异构体分离度的核磁共振和高效液相色谱比较研究
摘要:在之前的一项研究中,我们小组和 Machida 小组开发了衍生自 (+)-(18Crown-6)-2,3,11,12-四羧酸 (18-C-6-Ta) 用于 HPLC 研究(图 1).这些 Csp 已有效地应用于解析多种氨基酸和各种伯氨基化合物.此外,我们小组报道了 18-C-6-Ta 作为 NMR 手性溶剂化剂在 NMR 光谱中解析一些氨基酸分析物非常有效.因此,我们报道了手性冠醚选择剂 18-C-6-Ta 可用于通过 NMR 光谱对苯甘氨酸,丙氨酸和二苯丙氨酸的对映体鉴别.其他小组也报道了使用 18-C-6-Ta 作为手性 NMR 溶剂化剂的一些结果.尽管 HPLC 和 NMR 光谱的每种分析方法都已独立研究,但使用 18-C-6-Ta 作为手性选择剂通过两种分析方法对 α 氨基酸及其酯的对映异构体拆分的直接比较研究尚未发表.尤其是我们组仅报道了两种α-氨基酸酯的核磁共振对映异构体拆分结果.因此,在本研究中,我们在
Doi:10.5012/bkcs.2012.33.10.3481

专利信息

专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人：FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

专利号:US-11702652-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2009264300-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2020216836-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:IT-RM980061-A1
优先权日:1998-02-02
标 题 :PROCEDURE FOR THE PRODUCTION OF PEPTIDES COM INHIBITING PROPERTIES OF THE NS3 SYNTHESIS OF THE HCV VIRUS SO OBTAINABLE PEPTIDES AND PEPTIDES

专利号:US-2019330618-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries