CAS: 24812-90-6; Methyl 3-Amino-4-Methoxybenzoate

该化合物是一种有机化合物,其特点是芳香结构,包括一种配有氨基氨基氨基酸组和甲氧基组的苯甲酸混合物,该化合物一般是白色的,白色的,白色的固体,在有机溶剂中溶解,反映其疏水芳香特性;氨基氨基酸组的存在具有基本特性,而甲基氧组则可以影响其再活性和极性;该组通常用于有机合成,并可作为生产药品,农用化学品或其他精细化学品的中间体;该化合物的功能组表示,在各种化学反应中,包括酯化和化外反应中,氢联和再活性的潜力;此外,其生物活动可能与医药化学有关,因为各种药用酸衍生物已知有各种药用特性;处理和使用安全数据,如所有化学物质.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

methyl 4-methoxy-3-nitrobenzoate methyl iodide diazomethane 3-amino-4-methoxybenzoic acid3-chloro-4-methoxy benzoic acid methyl 3-chloro-p-anisate 3-amino-4-methoxybenzoic acid 4-Methoxy-3-((Z)-°Ctadec-9-enoylamino)-benzoic acid methyl ester

合成工艺路线路线简述

    4-甲氧基-3-硝基苯甲酸置于盐酸,铂体系中,化学反应生成3-氨基-4-甲氧基苯甲酸甲酯
    参考文献:The Synthesis Of 3',5'-Difluoro-Dl-Thyronine And 3,5-Diiodo-3',5'-Difluoro-Dl-Thyronine
    标题:The Synthesis Of 3',5'-Difluoro-Dl-Thyronine And 3,5-Diiodo-3',5'-Difluoro-Dl-Thyronine
    摘要:
    Doi:10.1021/ja01853A051

    海关参考信息

    专利信息


    专利号:US-7129357-B2
    优先权日:2003-09-15
    标题:Synthesis of quinoline 5-carboxamides useful for the preparation of PDE IV inhibitors
    发明人:ANDREWS DAVID R; TANG SUHAN; WU WENXUE; KALLINEY SAMI Y; SUDHAKAR ANANTHA; NIELSEN CHRISTOPHER
    权利人:SCHERING CORP
    摘要:In one embodiment, the present application discloses a process for making the compound of the formula:

    专利号:CA-2538591-A1
    优先权日:2003-09-15
    标题 :Synthesis of quinoline 5-carboxamides useful for the preparation of pde iv inhibitors

    专利号:WO-0053313-A2
    优先权日:1999-03-09
    标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

    专利号:EP-1836163-B1
    优先权日:2004-12-23
    标题 :Pyrrolidine derivatives for the treatment of a disease depending on the activity of renin
    发明人:BREITENSTEIN WERNER; COTTENS SYLVAIN; EHRHARDT CLAUS; JACOBY EDGAR; LORTHIOIS EDWIGE LILIANE JEANNE; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; SELLNER HOLGER; SIMIC OLIVER
    权利人:NOVARTIS AG
    摘要:Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on inappropriate activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on inappropriate activity of renin; the use of a compound of that class in the treatment of a disease that depends on inappropriate activity of renin; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound, a method for the manufacture of said substituted pyrrolidine compounds, and novel intermediates and partial steps for their synthesis are described. The substituted pyrrolidine compounds are especially of the formula I wherein the substituents are as described in the specification.

    专利号:WO-2005028471-A1
    优先权日:2003-09-15
    标题:Synthesis of quinoline 5-carboxamides useful for the preparation of pde iv inhibitors

    专利号:CN-1878765-A
    优先权日:2003-09-15
    标 题:Synthesis of quinoline 5-carboxamide for the preparation of PDE IV inhibitors
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    合成参考文献


    参考文献:10.1055/s-0036-1588371
    摘要:Morandi B, Legnani L, Bhawal B. Recent Developments in the Direct Synthesis of Unprotected Primary Amines. Synthesis. 2016 Dec 16;49(04):776–89. doi: 10.1055/s-0036-1588371.
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