CAS: 814-67-5; Propane-1,2-Dithiol

该化合物是一种该化合物是一种多功能的中间体.它的双功能结构使得能够应用切热,聚合物交叉连接和作为消毒剂. 1,2-Propanedithiol因其能够形成稳定的金属离子复合体并参与硫醇-乙烯反应而特别受到重视.它存在于普通有机溶剂中,但水溶性有限.由于易燃性和潜在毒性,适当的处理是必不可少的.该化合物通常用于制药,材料科学和专门化学合成.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号74-99-7 丙炔 | CAS号598-36-7 2-Propanethiol,... | CAS号78-75-1 1,2-二溴丙烷 | CAS号106-95-6 烯丙基溴 | CAS号3489-45-0 see 1,3-Dithiol... | CAS号7783-06-4 硫化氢 | CAS号7314-75-2 1,2-bis-thi°Cya... | CAS号925-89-3 prop-1-ene-1-thiol | CAS号102107-33-5 4-methyl-2-(2-p... | CAS号102107-32-4 2,4-dimethyl-2-... | CAS号100059-87-8 2,4-dimethyl-2-... | CAS号67-63-0 异丙醇 | CAS号5862-53-3 2,2,4-trimethyl... | CAS号5616-53-5 4-methyl-2-phen...

合成工艺路线路线简述

    1,2-二溴丙烷置于乙醇,Potassium Hydrosulfide体系中,化学反应生成 1,2-丙二硫醇
    参考文献:Hagelberg,Chemische Berichte,1890,Vol. 23,P. 1084
    标题:Hagelberg,Chemische Berichte,1890,Vol. 23,P. 1084

    专利信息


    专利号:US-5087759-A
    优先权日:1989-02-08
    标题:Synthesis of vicinal alkanedithiols
    发明人:VALLEE YANNICK; LABAT YVES
    权利人:ELF AQUITAINE
    摘要:The invention relates to the manufacture of vicinal alkanedithiols from the corresponding alkylene trithiocarbonates. n The method according to the invention consists in treating alkylene trithiocarbonate with an alkaline sulfide, followed by acidification of the reaction medium. n The method is particularly well-suited for the synthesis of ethanedithiol from ethylene trithiocarbonate.

    专利号:US-8115002-B2
    优先权日:2006-09-20
    标 题:Preparation of substituted morphinan-6-ones and salts and intermediates thereof
    发明人:WANG PETER X; MOSER FRANK W; CANTRELL GARY L; GROTE CHRISTOPHER W
    权利人:WANG PETER X; MOSER FRANK W; CANTRELL GARY L; GROTE CHRISTOPHER W; MALLINCKRODT LLC
    摘要:The present invention is directed to processes for the synthesis of morphinan-6-ones and salts, intermediates, and analogs thereof.

    专利号:US-8231848-B1
    优先权日:2012-04-10
    标题:One-pot synthesis of chalcopyrite-based semi-conductor nanoparticles
    发明人:REN YUHANG; SUN CHIVIN; SHUM KAI
    权利人:REN YUHANG; SUN CHIVIN; SHUM KAI; SUN HARMONICS LTD
    摘要:Ternary and quaternary Chalcopyrite CuInxGa1-xSySe2-y (CIGS, where 0≰x and y≰1) nanoparticles were synthesized from molecular single source precursors (SSPs) by a one-pot reaction in a high boiling solvent using salt(s) (i.e. NaCl as by-product) as heat transfer agent via conventional convective heating method. The nanoparticles sizes were 1.8 nm to 5.2 nm as reaction temperatures were varied from 150° C. to 190° C. with very high-yield. Tunable nanoparticle size is achieved through manipulation of reaction temperature, reaction time, and precursor concentrations. In addition, the method developed in this study was scalable to achieve ultra-large quantities production of tetragonal and quaternary Chalcopyrite CIGS nanoparticles.

    专利号:US-5565517-A
    优先权日:1994-11-16
    标题:Synthesis of organic polysulfide polymers
    发明人:EFNER HOWARD F; SHAW JAMES E
    权利人:PHILLIPS PETROLEUM CO
    摘要:A process for preparing an organic polysulfide polymer, such as polyethylene trisulfide, is provided which comprises contacting a dimercaptan such as 1,2-ethanedithiol with elemental sulfur using a basic catalyst wherein the dimercaptan, elemental sulfur, and basic catalyst are each present in an effective amount to effect the preparation of the organic polysulfide polymer. A process for controlling the molecular weight of an organic polysulfide polymer is also provided which comprises contacting a mercaptan with a dimercaptan and sulfur, in the presence of a basic catalyst, under conditions sufficient to prepare an organic polysulfide polymer.

    专利号:CN-114989235-A
    优先权日:2015-09-28
    标题:Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis

    专利号:CN-108779138-B
    优先权日:2015-09-28
    标题 :Design and synthesis of novel disulfide linker-based nucleotides for use as reversible terminators for DNA sequencing by synthesis
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    合成参考文献


    摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 1985. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Archives of Environmental Contamination and Toxicology 14:111-129.
    摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 2004. Toxicity, Repellency of Phytotoxicity of 979 Chemicals to Birds, Mammals and Plants. Research Report No. 04-01. National Wildlife Research Center, Fort Collins, Colorado. 118 pp. https://www.aphis.usda.gov/ws/nwrc/chem-effects-db/U_schafer041_2004.pdf
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