CAS: 108-41-8; 3-Chlorotoluene

上下游产品

CAS号108-88-3 甲苯 | CAS号4342-61-4 二氯四甲基二硅烷 | CAS号1711-06-4 间甲基苯甲酰氯 | CAS号108-39-4 间甲酚 | CAS号201230-82-2 carbon monoxide | CAS号5100-98-1 3-氯-2-碘甲苯 | CAS号108-44-1 3-甲基苯胺 | CAS号70450-41-8 1-chloro-3-(iod... | CAS号620-20-2 3-氯氯苄 | CAS号1422-76-0 m-methylbenzene... | CAS号1084-17-9 2-chloro-4-meth... | CAS号40137-29-9 4-氯-2-甲基苯甲醛 | CAS号50817-80-6 2-氯-4-甲基苯甲醛 | CAS号352-70-5 3-氟甲苯 | CAS号352-32-9 对氟甲苯 | CAS号95-52-3 邻氟甲苯 | CAS号3586-14-9 3-苯氧基甲苯 | CAS号5367-28-2 5-氯-2-硝基甲苯 | CAS号38939-88-7 3-氯-4-硝基甲苯 | CAS号5367-26-0 3-氯-2-硝基甲苯

M-Methylbenzenediazonium Tetrafluoroborate置于四甲基乙二胺,Potassium Chloride,苄基三乙基氯化铵,Copper(L) Chloride,Copper Dichloride体系中,用 乙腈 用作溶剂,化学反应 1.0H,以83%的收率获得3-氯甲苯
参考文献:Cu(I)/cu(II)/tmeda,New Effective Available Catalyst Of Sandmeyer Reaction
标题:Cu(I)/cu(II)/tmeda,New Effective Available Catalyst Of Sandmeyer Reaction
摘要:The System Cu(I)/cu(II)/n,N,N',N'-Tetramethylethylenediamine Is A Highly Efficient And Accessible Catalyst Of Sandmeyer Reaction. The Reaction Of Aryldiazonium Salts With Chlorides,Bromides,,Cyanides,And Thiocyanates Of Alkaline Metals In The Presence Of This Catalytic System Leads To The Formation Of The Corresponding Aryl Halides,Nitriles,And Thiocyanates In High Yields.
Doi:10.1134/s1070428012080040

专利信息

专利号:US-2010016607-A1
优先权日:2006-12-11
标题:Process for the Synthesis of Highly Active Binary Metal Fluoride as a Fluorinating Agent for Aromatics
发明人：DOLBIER JR WILLIAM R; JANMANCHI KRISHNA MURTHY
权利人:UNIV FLORIDA
摘要:The subject invention relates to a process for the synthesis of highly active binary metal fluoride system for the fluorination of aromatic compounds. Fluorinated aromatic compounds are valuable synthons for the chemical synthesis of pharmaceutical drugs and novel polymers. Fluorobenzene is used to control carbon content in steel manufacturing, is an intermediate for pharmaceuticals, pesticides and other organic compounds. Fluorobenzene is typically produced by the reaction of aniline and sodium nitrite in the presence of hydrogen fluoride. The present invention relates to a process for the synthesis of highly active binary metal fluoride system consists of copper (II) fluoride and aluminum (III) fluoride for the fluorination of aromatic compounds in gas phase and recycling of the reagent, in situ, using O 2 and HF.

专利号:US-8461357-B2
优先权日:2008-09-19
标题 :Expeditious synthesis of gibberellin A5 and esters thereof
发明人：FAIRWEATHER KELLY A; MANDER LEWIS N; PHARIS RICHARD P
权利人:FAIRWEATHER KELLY A; MANDER LEWIS N; PHARIS R P; UTI LIMITED PARTNERSHIP
摘要:An expeditious synthesis of gibberellin A 5 (GA 5 ) esters is presented, from which GA 5 may be prepared. The synthesis offers an inexpensive route of few steps to these compounds, starting from gibberellin A 3 (GA 3 ) esters in the presence of a metal hydride.

专利号:US-8450365-B2
优先权日:2009-05-12
标 题 :Efficient synthesis of galanthamine
发明人：MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ
权利人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ; UNIV TEXAS
摘要:The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine related derivatives and intermediates thereof. In further embodiments, the invention relates to methods for improving the efficiency and overall yield of galanthamine and intermediates thereof.

专利号:WO-2024137329-A1
优先权日:2022-12-20
标 题:Methods for the synthesis of complement factor d inhibitors and intermediates thereof
发明人：HASHIMOTO AKIHIRO; TIPPARAJU SURESH KUMAR
权利人:ALEXION PHARMA INC
摘要:The present disclosure provides methods for the synthesis of complement factor D inhibitors and intermediates thereof.

专利号:US-8471045-B2
优先权日:2007-04-03
标题 :Synthesis of statins
发明人：CASAR ZDENKO; MESAR TOMAZ; KOPITAR GREGOR; MRAK PETER; OSLAJ MATEJ
权利人:CASAR ZDENKO; MESAR TOMAZ; KOPITAR GREGOR; MRAK PETER; OSLAJ MATEJ; LEK PHARMACEUTICALS
摘要:The process for the synthesis of statins featuring the use of an early intermediate (4R,6S)-6-(dialkoxymethyl)tetrahydro-2H-pyran-2,4-diol which already possesses the desired stereochemistry corresponding to the final statin.

专利号:US-6958420-B2
优先权日:2002-07-19
标题:Synthesis of aminoarylboronic esters and substituted anilines from arenes via catalytic C-H activation/borylation/amination and uses thereof
发明人：MALECZKA JR ROBERT E; SMITH III MILTON R; HOLMES DANIEL
权利人:UNIV MICHIGAN STATE
摘要:A process is described for synthesizing aminoarylboronic esters of the general formula n n nwherein R, R 2 , and R 3 are each an alkyl, aryl, vinyl, alkoxy, carboxylic esters, amides, or halogen; Ar is any variety of phenyl, naphthyl, anthracyl, heteroaryl; and R 1 is alkyl, hydrogen, or aryl. The aminoarylboronic esters are produced via the metal-catalyzed coupling of arylboronic esters of the general formula n n nwherein R and R 1 are any non-interfering group and X is chloro, bromo, iodo, triflates, or nonaflates to amines (primary and secondary). In particular, a process is described for the synthesis of the aminoarylboronic esters via a step-wise or tandem process in which one catalytic event is a metal-catalyzed borylation and the other catalytic event is a metal-catalyzed amination.