CAS: 370069-31-1; 1-Boc-2-(Aminomethyl)Piperidine

相似化合物

475105-35-2 683233-14-9 141774-61-0

上下游产品

Tert-Butyl (S)-2-[(2,2,2-Trifluoroacetamido)Methyl]Piperidine-1-Carboxylate 475105-34-1

Tert-Butyl (S)-2-[(2,2,2-Trifluoroacetamido)Methyl]Piperidine-1-Carboxylate,Potassium Carbonate置于dichloromethane Hydrate,Brine,Silica Gel,Ammonia Methanol,二氯甲烷体系中,用 甲醇 用作溶剂,化学反应 16.0H,以to Give The Title Compound (8.82 G) Of Description 1的收率获得1-Boc-2-氨甲基哌啶
参考文献:N-Aroyl Cyclic Amines
标题:N-Aroyl Cyclic Amines
摘要:本发明涉及具有以下式子的n-芳酰基环状胺衍生物: 其中取代基变量如定义在此处,并且它们的用途作为药物.

专利信息

专利号:US-8772301-B2
优先权日:2009-12-18
标题 :Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
发明人：HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D
权利人:HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D; SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.