CAS: 528-50-7; (2R,3R,4R,5R)-2,3,5,6-Tetrahydroxy-4-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Hexanal

该化合物是一种分离体,由两个β-D-甘蔗单位组成,由β(14) 甘醇结合物连接,是纤维素的一个关键结构组成部分,是生物化学和酶研究中有价值的基质.该化合物广泛用于研究,以调查纤维素活动,碳水化合物新陈代谢和甘代谢机制.其高纯度和定义明确的结构使它成为分析应用的可靠标准,包括染色体和光谱学.D-(+)-Cellobiose 也用于微生物发酵过程和生物燃料开发的研究,其在水溶液中的稳定性和溶性进一步提高了其在实验室环境中的效用.

结构式图片

相似化合物

69-79-4 5965-66-2 6291-42-5

上下游产品

CAS号6918-41-8 cellotetraose | CAS号2240-27-9 纤维五糖 | CAS号2478-35-5 纤维六糖 | CAS号34620-78-5 麦芽七糖 | CAS号10323-20-3 D-阿拉伯糖 | CAS号50-99-7 D(+)-无水葡萄糖 | CAS号5077-26-9 O3-β-D-Glucopyr... | CAS号123-76-2 乙酰丙酸 | CAS号67-47-0 5-羟甲基糠醛 | CAS号78-98-8 丙酮醛

合成工艺路线路线简述

    D-(+)-纤维四糖置于cellulosimicrobium Cellulans Strain 21 Gh1 β-Glucosidase Ccbgl1B,Recombinant,Molecular Weight: 57 Kda,水体系中,用 Aq. Phosphate Buffer 作为反应溶剂,化学反应 0.34H,反应生成 D-纤维二糖
    参考文献:Cloning,Expression And Biochemical Characterization Of A Gh1 β-Glucosidase From Cellulosimicrobium Cellulans
    标题:Cloning,Expression And Biochemical Characterization Of A Gh1 β-Glucosidase From Cellulosimicrobium Cellulans
    摘要:Beta-Glucosidase Plays An Important Role In The Degradation Of Cellulose. In This Study,A Novel-Glucosidase Ccbgl1B Gene For A Glycosyl Hydrolase (Gh) Family 1 Enzyme Was Cloned From The Genome Of Cellulosimicrobium Cellulans And Expressed In Escherichia Coli Bl21 Cells. The Sequence Contained An Open Reading Frame Of 1494Bp,Encoded A Polypeptide Of 497Amino Acid Residues. The Recombinant Protein Ccbgl1B Was Purified By Ni Sepharose Fastflow Affinity Chromatography And Had A Molecular Weight Of 57Kda,As Judged By Sds-Page. The Optimum-Glucosidase Activity Was Observed At 55 Degrees C And Ph 6.0. Recombinant Ccbgl1B Was Found To Be Most Active Against Aryl-Glycosides P-Nitrophenyl--D-Glucopyranoside (Pnpglc),Followed By P-Nitrophenyl--D-Galactopyranoside (Pnpgal). Using Disaccharides As Substrates,The Enzyme Efficiently Cleaved-Linked Glucosyl-Disaccharides,Including Sophorose (-1,2-),Laminaribiose (-1,3-) And Cellobiose (-1,4-). In Addition,A Range Of Cello-Oligosaccharides Including Cellotriose,Cellotetraose And Cellopentaose Were Hydrolysed By Ccbgl1B To Produce Glucose. The Interaction Mode Between The Enzyme And The Substrates Driving The Reaction Was Modelled Using A Molecular Docking Approach. Understanding How The Gh1 Enzyme Ccbgl1B From C. Cellulans Works,Particularly Its Activity Against Cello-Oligosaccharides,Would Be Potentially Useful For Biotechnological Applications Of Cellulose Degradation.
    DOI:10.1080/10242422.2017.1395415

    海关参考信息

    专利信息


    专利号:US-11473116-B2
    优先权日:2018-02-23
    标题 :Synthesis of glucan comprising alpha-1,3 glycosidic linkages with phosphorylase enzymes
    发明人:YU ZHEYONG; KRALJ SLAVKO; ZHANG ZHENGHONG; HOWE LAURIE A
    权利人:NUTRITION & BIOSCIENCES USA 4 INC
    摘要:Reaction compositions are disclosed herein comprising at least water, beta-glucose -1-phosphate (beta-G1P), an acceptor molecule, and an alpha-1,3-glucan phosphorylase enzyme. These reactions can synthesize oligosaccharides and polysaccharides with alpha-1,3 glycosidic linkages. Further disclosed are alpha-1,3-glucan phosphorylase enzymes and methods of use thereof.

    专利号:US-8846759-B2
    优先权日:2009-12-24
    标题 :Low-caloric high-protein nutritional composition for the stimulation of muscle protein synthesis
    发明人:LUIKING YVETTE CHARLOTTE; VERLAAN GEORGE; JOURDAN MARION
    权利人:LUIKING YVETTE CHARLOTTE; VERLAAN GEORGE; JOURDAN MARION; NUTRICIA NV
    摘要:The present invention relates to the use of a low-caloric high-protein nutritional composition for use in the prevention or treatment of a disease or condition in a mammal, which involves muscle decline, as well as to specific low-caloric high-protein nutritional compositions for stimulating muscle protein synthesis in a mammal. In particular, the invention relates to the use of a nutritional composition comprising per 100 kcal: (i) at least about 12 g of proteinaceous matter which comprises at least about 80 weight % of whey protein, relative to the total proteinaceous matter, and which comprises at least about 11 weight % of leucine, relative to the total proteinaceous matter, of which at least about 20 weight % is in a free form, relative to the total leucine, (ii) a source of fat and a source of digestible carbohydrates, for the prevention or treatment of a disease or condition which involves muscle decline in a mammal, especially an elderly mammal, wherein the nutritional composition is administered as 1 to 2 servings daily, each serving comprising between 80 and 200 kcal.

    专利号:US-9339782-B1
    优先权日:2004-11-18
    标题 :Electrode array device having an adsorbed porous reaction layer
    发明人:GINDILIS ANDREI
    权利人:CUSTOMARRAY INC
    摘要:There is disclosed an electrode array device having an adsorbed porous reaction layer for improved synthesis quality. The array comprises a plurality of electrodes on a substrate, wherein the electrodes are electronically connected to a computer control system. The array has an adsorbed porous reaction layer on the plurality of electrodes, wherein the adsorbed porous reaction layer comprises a chemical species having at least one hydroxyl group. In the preferred embodiment, the reaction layer is sucrose. A method for preparing an electrode array for improved synthesis quality is disclosed. The method comprises a cleaning method and a method of attachment of a reaction layer. The cleaning method comprises a plasma cleaning method and a chemical cleaning method. The reaction layer is attached after cleaning by exposing the microarray to a solution containing the chemical species having at least one hydroxyl group.

    专利号:EP-2590521-B1
    优先权日:2010-07-07
    标 题:Nutritional composition for the stimulation of muscle protein synthesis

    专利号:US-2015290223-A1
    优先权日:2010-07-07
    标题 :Nutritional Composition for the Stimulation of Muscle Protein Synthesis

    专利号:US-2013203658-A1
    优先权日:2009-12-24
    标题 :Low-Caloric High-Protein Nutritional Composition for the Stimulation of Muscle Protein Synthesis
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    合成参考文献


    参考文献:10.1007/978-3-030-78444-7_39
    摘要:Sánchez-Vega R, Chávez-Martínez A, Tirado-Gallegos JM, Reyes-Jurado F, Ochoa-Velasco CE, Avila-Sosa R. Opuntia spp. Products and By-products as a Potential Source of Edible Films and Coatings. 2021. In: Opuntia spp.: Chemistry, Bioactivity and Industrial Applications.
    参考文献:10.1007/978-981-99-3435-5_7
    摘要:Kaur D, Singh A, Dalal S, Sharma J. Rice Straw Waste Utilization for Nanoparticles Synthesis and Their Various Applications. 2023. In: Smart Nanomaterials Technology.
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