CAS: 889865-45-6; 2,3-Dichloro-4-Iodopyridine

• 英文名称2,3-Dichloro-4-Iodopyridine
• 中文名称2,3-二氯-4-碘吡啶
• IUPAC名称2,3-dichloro-4-iodopyridine
• 其它别名Wrpbpdpxvubwcr-Uhfffaoysa-N; 2,3-Dichloro-4-Iodopyridine; 2,3-Dichloro-4-Iodo-Pyridine; 2-Methyl-4-Nitrophenylisothiocyanate; Pyridin
• CAS编号889865-45-6
• MFCD编号:MFCD11857737
• EINECS号:662-872-4
• 分子式:C5H2Cl2IN
• 分子量:273.89
• 产品CID: 1909998
• 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物

• 相似结构搜索
• InChIKey: WRPBPDPXVUBWCR-UHFFFAOYSA-N
• InChI=1S/C5H2Cl2IN/c6-4-3(8)1-2-9-5(4)7/h1-2H…
• 计算化学: 氢键受体数1.0氢键供体数0.0可旋转键数0.0

相似化合物

物理性质

• 熔点109-113°C
• 沸点284.3±35.0 °C at 760 mmHg
• 闪点125.8±25.9 °C
• 密度2.1±0.1 g/cm3
• pKa:-0.80±0.10(预测)
• PSA:12.89
• LogP:2.993
• 折射率1.652
• 蒸汽压0.0±0.6 mmHg at 25°C
• 外观形态米色固体
• 储存条件在惰性气体(氮气或氩气)下 2–8 °C

MSDS等安全信息

• GHS象形图
• GHS符号GHS06;
  注释: Skull and crossbones
• 危险类别急性毒性 类别3(经口)
  严重眼刺激 类别2
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2A
• 警示词Danger(危险)
• 危险描述H301 |吞咽会中毒.
  H319 |造成严重眼刺激.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
• 防范说明P264-P270-P280-P330-P405-P501
• 危险等级6.1
• UN编号2811.0
• 危险品标志Xn
• 包装等级Ⅲ
• 安全声明26
• 危险类别码22-36
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 2402-77-9 = 889865-45-6
  反应条件:1.1 Reagents: Butyllithium,2,2,6,6-Tetramethylpiperidine Solvents: Diethyl Ether,Hexane; -78 °C; 10 Min,-78 °C1.2 Solvents: Tetrahydrofuran; -78 °C; 30 Min,-78 °C1.3 Reagents: Iodine Solvents: Tetrahydrofuran; -78 °C; Overnight,-78 °C -> Rt1.4 Reagents: Sodium Thiosulfate Solvents: Water
  标题:Regiocontrolled Microwave Assisted Bifunctionalization Of 7,8-Dihalogenated Imidazo[1,2-α]Pyridines: A One Pot Double-Coupling Approach
  作者:Marie,Emilie; Boucle,Sebastien; Enguehard-Gueiffier,Cecile; Gueiffier,Alain
  参考文献:Molecules 日期:2012 卷标:17 页码:10683-10707]
  
  2402-77-9 = 889865-45-6
  反应条件:1.1 Reagents: Butyllithium,2,2,6,6-Tetramethylpiperidine Solvents: Diethyl Ether,Hexane; -78 °C; 10 Min,-78 °C1.2 Solvents: Tetrahydrofuran; -78 °C; 45 Min,-78 °C1.3 Reagents: Iodine Solvents: Tetrahydrofuran; -78 °C -> Rt; 16 H,Rt1.4 Reagents: Sodium Thiosulfate Solvents: Water
  标题:Imidazo[1,2-A]Pyridines: Orally Active Positive Allosteric Modulators Of The Metabotropic Glutamate 2 Receptor
  作者:Trabanco,Andres A.; Tresadern,Gary; Macdonald,Gregor J.; Vega,Juan Antonio; De Lucas,Ana Isabel; Et Al
  参考文献:Journal Of Medicinal Chemistry 日期:2012 卷标:55(6) 页码:2688-2701]
  
  2402-77-9 = 889865-45-6
  反应条件:1.1 Reagents: Butyllithium,2,2,6,6-Tetramethylpiperidine,Dichloro(N,N,N′,N′-Tetramethylethylenediamine)Zinc Solvents: Tetrahydrofuran,Hexane; 15 Min,0 °C1.2 2 H,Rt1.3 Reagents: Iodine Solvents: Tetrahydrofuran; Overnight,Rt
  标题:Deprotonative Metalation Of Chloro- And Bromopyridines Using Amido-Based Bimetallic Species And Regioselectivity-Computed Ch Acidity Relationships
  作者:Snegaroff,Katia; Nguyen,Tan Tai; Marquise,Nada; Halauko,Yury S.; Harford,Philip J.; Et Al
  参考文献:Chemistry - A European Journal 日期:2011 卷标:17(47) 页码:13284-13297]
  
  2402-77-9 = 889865-45-6
  反应条件:1.1 Reagents: Piperidine,2,2,6,6-Tetramethyl-,Lithium Salt (1:1) Solvents: Tetrahydrofuran,Hexane; -78 °C; 30 Min,-78 °C1.2 Reagents: Iodine Solvents: Tetrahydrofuran; 1 H,-78 °C -> Rt1.3 Reagents: Sodium Thiosulfate Solvents: Water; Rt
  标题:Synthesis And Evaluation Of The Anticoccidial Activity Of Trifluoropyrido[1,2-A]Pyrimidin-2-One Derivatives
  作者:Silpa,Laurence; Niepceron,Alisson; Laurent,Fabrice; Brossier,Fabien; Penichon,Melanie; Et Al
  参考文献:Bioorganic & Medicinal Chemistry Letters 日期:2016 卷标:26(1) 页码:114-120

海关参考信息

• 2933310010-吡啶
  2939800000-其他生物碱
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

专利信息

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管