CAS: 95-85-2; 2-Amino-4-Chlorophenol

上下游产品

p-chloro-o-nitrophenol sulfuric acid mono-(2-amino-4-chloro-phenyl ester) 2-hydroxy-5-chloroazobenzene O-(4-chlorophenyl)hydroxylamine 3-[1-(5-chloro-2-hydroxy-phenylimino)-ethyl]-dihydro-furan-2-one (5-chloro-2-hydroxy-phenyl)-carbamic acid ethyl ester N-(5-chloro-2-hydroxyphenyl)acetamide 4-chloro-2-(4-nitro-benzylidenamino)-phenol

4-氯-2-硝基苯酚置于sodium Tetrahydroborate,水,Potassium Carbonate体系中,化学反应 7.0H,以96%的收率获得产物4-氯-2-氨基苯酚
参考文献:高多孔铜负载磁性纳米催化剂:由纤维素织构的火山浮石制成,用于硝基苯衍生物的还原
标题:高多孔铜负载磁性纳米催化剂:由纤维素织构的火山浮石制成,用于硝基苯衍生物的还原
摘要:在此,提出了一种新颖设计的非均相催化系统,该系统由火山浮石磁性颗粒(vpmp),作为天然聚合物基质的纤维素(cls)和铜纳米颗粒(cu Np)构成.此外,为了增强 Vpmp 的固有磁性,制备了氧化铁 (Fe 3 O 4) 纳米颗粒,并通过原位过程将其掺入结构中.作为其首要的优异性能,所设计的复合材料非常符合绿色化学原理,因为它含有天然成分.所设计的复合材料结构的另一个亮点是作为复合材料结构核心的vpmp的显着孔隙率(表面积:84.473 M 2 G-1).这种巨大的孔隙率导致只需使用少量(0.05 克)颗粒即可达到催化目的.然而,主要的表征方法,例如傅里叶变换红外光谱和能量色散x射线光谱,热重分析和电子显微镜,表明球形金属颗粒(fe和cu氧化物)成功分布在vpmp的表面上和 Cls 矩阵.此外,振动样品磁力计分析证实,通过添加fe 3 O 4纳米颗粒,复合材料的磁性能(1.5 Emu
DOI:10.1039/d1Ra03538J

专利信息

专利号:US-9567308-B1
优先权日:2015-07-23
标 题:Process for the synthesis of chlorzoxazone
发明人：BOGOGNA LUIGI; CICIONE LAVINIA; BAROZZA ALESSANDRO; ROLETTO JACOPO; PAISSONI PAOLO
权利人:PROCOS SPA
摘要:Disclosed is a process for the synthesis of chlorzoxazone (1) from 4-chloro-2-aminophenol and ethyl chloroformate in the presence of a base. n n n n n n n n n n The process is particularly advantageous because it uses ethyl chloroformate instead of triphosgene, a highly dangerous reagent that releases phosgene and must be handled with extremely strict procedures to guarantee the safety of operators in industrial facilities. n Ethyl chloroformate allows the possibility of working with a number of solvents, including water. n The yield and purity of the product obtained are very high.

专利号:US-6177572-B1
优先权日:1997-08-20
标题 :Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use
发明人：WANG FENGJIANG
权利人:SEPRACOR INC
摘要:Methods for preparing benzoxazoles and benzothiazoles on solid supports. Substituted benzothiazoles and benzoxazoles, libraries of the compounds, and methods of using the compounds are also disclosed.

专利号:US-4005067-A
优先权日:1970-10-28
标题 :Process for the synthesis of nitrite ion-containing 1:1 complexes of cobalt and metallizable monoazo or azomethine compounds and such complexes
发明人：DORE JACKY
权利人:SANDOZ LTD
摘要:By metallization of metallizable monoazo or azomethine dyes with cobalt-donating compounds in the presence of a nitrite, especially NaNO 2 , 1:1 cobalt complexes containing a nitrite ion are obtained in a high degree of metallization which can be reacted with metallizable monoazo or azomethine dyes to give very homogeneous 2:1 cobalt complexes in a high degree of purity. This is particularly advantageous when asymmetrical 2:1 cobalt complexes are to be prepared. The process is particularly useful for the preparation of nitrite ion-containing 1:1 complexes of cobalt and a monoazo compound of the formula ##STR1## wherein X is --OH or --NHR, n wherein R is hydrogen or a substituted or unsubstituted alkyl, cycloalkyl, phenyl or naphthyl group, n Ring A is further unsubstituted or further substituted by at least one halo, nitro or optionally substituted alkyl, alkoxy or sulfamoyl substituent, and n The naphthalene ring is further unsubstituted or further substituted by at least one hydroxy, sulfamoyl or acylamino substituent.

专利号:US-2016194279-A1
优先权日:2012-12-09
标 题 :One pot process for the conversion of aroyl chlorides to acyl thioureas
发明人：CHEPURI VENKATA RAMANA; BEERAN SENTHILKUMAR
权利人:COUNCIL SCIENT IND RES
摘要:The present invention disclose an improved one pot process for synthesis of acyl thioureas of formula (I), with yield greater than 80%, from aroyl chlorides of formula (I) wherein, R′ is an aryl or a heteroarylene group substituted with one or more groups selected from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino, carboxyl, ester, halogenated hydrocarbon or an aryl or heteroaryl; R″ and R′″ are selected independently from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino or halogenated hydrocarbon.

专利号:US-2016168138-A1
优先权日:2013-07-15
标题:Process for the preparation of suvorexant and intermediates useful in the synthesis of suvorexant
发明人：IQBAL JAVED; DAHANUKAR VILAS HARESHWAR; ORUGANTI SRINIVAS; KANDAGATLA BHASKAR
权利人:REDDY S LAB LIMTED DR
摘要:A novel processes for the preparation of suvorexant (formula I), its related compounds and its intermediates that are simple, economical and commercially viable. (I)

专利号:US-7550510-B2
优先权日:2001-07-06
标 题 :Solid phase synthesis of arylretinamides
发明人：CURLEY JR ROBERT W; MERSHON SERENA M; BARNETT DEREK W; CLAGETT-DAME MARGARET; CHAPMAN JASON S
权利人:WISCONSIN ALUMNI RES FOUND
摘要:A solid phase synthetic method for preparing arylretinamides is provided. The method comprises reacting hexachloroacetone with a solvent-suspended resin-bound triphenylphosphine to provide a suspension comprising an activated chlorinating reagent; reacting retinoic acid with the activated chlorinating reagent to provide retinoyl chloride; adding pyridine and a select arylamine to the resulting mixture; and stirring the resulting mixture for a time and at a temperature sufficient for the select arylamine to react with the retinoyl chloride and provide the arylretinamide. Also provided, are select arylretinamides that can be prepared by the present method, and methods of using such arylretinamides to induce apoptosis in cancer cells.