CAS: 121219-12-3; (4-Pentylphenyl)Boronic Acid

相似化合物

1359844-02-2 105365-50-2 256383-45-6

上下游产品

CAS号4737-50-2 正戊基硼酸 | CAS号17763-80-3 4-硝基苯基三氟甲磺酸酯 | CAS号33228-44-3 4-戊基苯胺 | CAS号95857-32-2 1-nitro-4-penty... | CAS号85017-60-3 1-碘-4-正戊烷基苯 | CAS号40817-08-1 4'-正戊基-4-氰基联苯 | CAS号521-35-7 大麻酚 | CAS号7116-96-3 对戊基联苯 | CAS号60040-14-4 4-(4-pentylphen... | CAS号163129-11-1 4-戊基-4-溴-3-氟联苯

4-硝基苯酚三氟甲基磺酸酯置于2-双环己基膦-2',6'-二甲氧基联苯,盐酸,Potassium Phosphate Monohydrate,Potassium Hydrogen Fluoride,Palladium On Activated Charcoal,氢气,Palladium Diacetate,三乙胺,Sodium Nitrite体系中,用 1,4-二氧六环,甲醇,乙醇,水,甲苯 用作溶剂,化学反应 1.5H,反应生成4-戊基苯硼酸
参考文献:Design And Synthesis Of Boronic Acid Inhibitors Of Endothelial Lipase
标题:Design And Synthesis Of Boronic Acid Inhibitors Of Endothelial Lipase
摘要:Endothelial Lipase (El) And Lipoprotein Lipase (Lpl) Are Homologous Lipases That Act On Plasma Lipoproteins. El Is Predominantly A Phospholipase And Appears To Be A Key Regulator Of Plasma Hdl-C. Lpl Is Mainly A Triglyceride Lipase Regulating (V)Ldl Levels. The Existing Biological Data Indicate That Inhibitors Selective For El Over Lpl Should Have Anti-Atherogenic Activity,Mainly Through Increasing Plasma Hdl-C Levels. We Report Here The Synthesis Of Alkyl,Aryl,Or Acyl-Substituted Phenylboronic Acids That Inhibit El. Many Of The Inhibitors Evaluated Proved To Be Nearly Equally Potent Against Both El And Lpl,But Several Exhibited Moderate To Good Selectivity For El. (C) 2011 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2011.12.043

专利信息

专利号:US-6121448-A
优先权日:1995-03-28
标题 :Pyrimidine compounds
发明人：LEWIS ROBERT ANDREWS; GOODBY JOHN WILLIAM; TOYNE KENNETH JOHNSON; HIRD MICHAEL
权利人:SECR DEFENCE BRIT
摘要:The synthesis of novel compound (I) is described: 5-bromo-2-iodopyrimidine may be used for the synthesis of a range of chemical compounds both known and novel. The synthesis of a number of novel liquid crystalline compounds is described.

专利号:CN-106478627-A
优先权日:2016-08-30
标 题 :A kind of 6,12,18-triaryl-5,11,17-benzotriquinoline derivative and its synthesis method