CAS: 2447-54-3; 13-Methyl-[1,3]Dioxolo[4',5':4,5]Benzo[1,2-C][1,3]Dioxolo[4,5-I]Phenanthridin-13-Ium

上下游产品

CAS号3606-45-9 二氢血根碱 | CAS号87264-51-5 protopine N-oxide | CAS号130-86-9 原阿片碱 | CAS号3606-45-9 二氢血根碱 | CAS号28342-31-6 6-乙氧基二氢血根碱 | CAS号37687-34-6 6-丙酮基二氢血根碱

原阿片碱置于oxidase Enzyme,还原型辅酶ii(Nadph)四钠盐体系中,化学反应 0.33H,反应生成血根碱
参考文献:一步法从原藤中酶法合成二氢血红碱
标题:一步法从原藤中酶法合成二氢血红碱
摘要:已经发现并表征了一种微粒体细胞色素p-450 Nadph依赖性酶,该酶使原皮中的碳6羟基化.单加氧酶反应产生6-羟基protopine,其自发地重排形成二氢血红碱碱.
Doi:10.1016/s0040-4039(00)80829-1

专利信息

专利号:WO-2025031833-A1
优先权日:2023-08-04
标 题:Recombinant strain and use thereof in production of scoulerine
发明人：CHEN YUN; JIAO XIANG
权利人:CHRYSEA LTD; CHEN YUN
摘要:Disclosed are recombinant yeast strains and a use thereof in the production of a benzylisoquinoline alkaloid. The recombinant yeast strains comprise berberine bridge enzyme. De novo synthesis of scoulerine and a benzylisoquinoline alkaloid is achieved through multiple strategies, and the yield thereof is significantly increased. The recombinant yeast strains provided by the present invention can produce scoulerine and other benzylisoquinoline alkaloids at high efficiency, and has important value in applications.

专利号:EP-0354945-B1
优先权日:1988-01-13
标 题 :Process for the enhancement of enzyme activities and synthetic efficiency in microorganisms and higher plants
发明人：FIEDLER FRANZ; ZENK MEINHART H; GUNDLACH HEIDRUN; WEBER ALFRED; KENNECKE MARIO
权利人:SCHERING AG
摘要:In the process disclosed, the organisms are brought into contact witn inactivated elicitor-containing microorganisms, fragments of the latter, or excretions of elicitor-containing microorganisms. Only inactivated elicitor-containing bacteria, fragments of the latter, or excretions of elicitor-containing bacteria may be used to activate enzymes and promote synthesis in non-microbial organisms. The process can be used, for example, to promote synthesis in microorganisms or plants which produce pigments, antibiotics, alkaloids or phytoalexins or to activate enzymes in microorganisms capable of transforming steroids.

专利号:US-12180228-B2
优先权日:2019-06-05
标题:Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof
发明人：MOVASSAGHI MOHAMMAD; OLSSON CHASE ROBERT; SCOTT TONY Z; CHEAH JAIME; PAYETTE JOSHUA NATHANIEL
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The present disclosure provides, e.g., compounds, compositions, kits, methods of synthesis, and methods of use, involving epipolythiodiketopiperazines and polythiodiketopiperazines.

专利号:WO-2020107548-A1
优先权日:2018-11-27
标 题:Highly efficient method for catalyzing synthesis of sanguinarine and chelerythrine

专利号:US-7989004-B2
优先权日:2004-05-27
标题:Antitubercular extracts of Salicornia brachiata
发明人：RATHOD MEENA RAJNIKANT; SHETHIA BHUPENDRA DHANVANTRAI; PANDYA JAYANT BATUKRAL; GHOSH PUSHPITO KUMAR; DODIA PRAKASH JAGIVANBHAL; SRIVASTAVA BRAHM S; SRIVASTAVA RANJANA; SRIVASTAVA ANIL; CHATURVEDI VINITA; VAIRAMANI MARIAPPANADAR
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to enhancement of anti-tubercular activity of active fraction isolated from Salicornia brachiata . The invention also discloses the non-toxic nature of the fraction and positively identifies Sucrose as its main constituent. Pure Sucrose is shown to have no anti-tubercular activity indicating thereby that activity of the fraction resides in one or more of the minor constituents. The minor constituents are shown to be relatively low molecular weight entities and a chromatographic technique is disclosed for separating them from the bulk sucrose to probe their activities and structures in detail, as also the possibility of their synthesis if the leads thrown up are novel.

专利号:EP-3137618-A1
优先权日:2014-04-29
标 题 :Improved methods for making and using polynucleotide sequences in the synthesis of alkaloid compounds