CAS: 7314-44-5; (2,4-Dimethoxyphenyl)Methanol

上下游产品

CAS号613-45-6 2,4-二甲氧基苯甲醛 | CAS号91-52-1 2,4-二甲氧基苯甲酸 | CAS号67-56-1 甲醇 | CAS号6496-89-5 2,4-二甲氧基苯乙酸 | CAS号55791-52-1 2,4-二甲氧基苄基氯 | CAS号2150-41-6 2,4-二甲氧基苯甲酸甲酯 | CAS号91-52-1 2,4-二甲氧基苯甲酸 | CAS号102408-71-9 trimethyl 5-hyd... | CAS号613-45-6 2,4-二甲氧基苯甲醛 | CAS号91330-41-5 6-hydroxy-7H-4,... | CAS号604-84-2 phenanthrene-9,... | CAS号17715-70-7 1-氟-2,4-二甲氧基苯 | CAS号161919-74-0 2,4-二甲氧基苄基溴

2,4-二甲氧基苯甲酸置于sodium Tetrahydroborate,Sodium Sulfate,3,4,5-三氟苯硼酸体系中,用 四氢呋喃 作为反应溶剂,化学反应 10.0H,以99%的收率获得产物2,4-二甲氧基苄醇
参考文献:使用3,4,5-三氟苯基硼酸和硼氢化钠将一氧化碳非常简单,方便,温和地一锅还原为醇
标题:使用3,4,5-三氟苯基硼酸和硼氢化钠将一氧化碳非常简单,方便,温和地一锅还原为醇
摘要:由羧酸和3,4,5-三氟苯基硼酸原位形成的酰氧基硼中间体在thf中与硼氢化钠反应反应生成醇,收率高至高.
DOI:10.1016/s0040-4039(03)00035-2

专利信息

专利号:US-6448058-B1
优先权日:1997-09-12
标 题:Methods for solid phase synthesis of mercapto compounds and derivatives, combinatorial libraries thereof and compositions obtained thereby
发明人：PATEL DINESH V; NGU KHEHYONG; ZHOU JIANPING
权利人:VERSICOR INC
摘要:Methods of preparing combinatorial libraries of mercapto (thiol) compounds them and compositions obtained therefrom are disclosed. The compounds are synthesized on a solid support. Following synthesis, the compounds are optionally cleaved from the support. One such method of synthesis involves attack of an S-protected nucleophile on a resin functionalized with a leaving group. The invention also provides for screening the mercapto compounds for bioactive compounds; in particular, for inhibitors of MMPs.

专利号:US-2014309424-A1
优先权日:2011-06-30
标题:Direct synthesis of 18f-fluoromethoxy compounds for pet imaging and the provision of new precursors for direct radiosynthesis of protected derivatives of o-([18f] fluoromethyl) tyrosine
发明人：BRUMBY THOMAS; GRAHAM KEITH; KRUGER MARTIN
权利人:BRUMBY THOMAS; GRAHAM KEITH; KRUGER MARTIN; PIRAMAL IMAGING SA
摘要:The invention describes novel direct synthesis methods for converting a precursor into a PET-tracer with a 18 F-fluoromethoxy-group. The invention is also directed to novel and stable precursors for the direct radiosynthesis of protected derivatives of O—([ 18 F]Fluoromethyl)tyrosines.

专利号:US-6906046-B2
优先权日:2000-12-22
标题 :Pharmaceutical uses and synthesis of benzobicyclooctanes
发明人：JACKSON RANDY W; DARWISH IHAB; BAUGHMAN TED A; HOWBERT J JEFFRY
权利人:CELLTECH R & D INC
摘要:Benzobicyclooctane compounds, their use in inhibiting cellular events involving TNF-α and IL-8, and in the treatment of inflammation events in general; a combinatorial library of diverse bicyclooctanes and process for their synthesis as a library and as individual compounds.

专利号:US-9045381-B2
优先权日:2010-10-19
标 题:Ruthenium complexes and their uses in processes for formation and/or hydrogenation of esters, amides and derivatives thereof
发明人：MILSTEIN DAVID; BALARAMAN EKAMBARAM; GUNANATHAN CHIDAMBARAM; GNANAPRAKASAM BOOPATHY; ZHANG JING
权利人:MILSTEIN DAVID; BALARAMAN EKAMBARAM; GUNANATHAN CHIDAMBARAM; GNANAPRAKASAM BOOPATHY; ZHANG JING; YEDA RES & DEV
摘要:The present invention relates to novel Ruthenium catalysts and related borohydride complexes, and the use of such catalysts, inter alia, for (1) hydrogenation of amides (including polyamides) to alcohols and amines; (2) preparing amides from alcohols with amines (including the preparation of polyamides (e.g., polypeptides) by reacting dialcohols and diamines and/or by polymerization of amino alcohols); (3) hydrogenation of esters to alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di-lactones) or polyesters); (4) hydrogenation of organic carbonates (including polycarbonates) to alcohols and hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (5) dehydrogenative coupling of alcohols to esters; (6) hydrogenation of secondary alcohols to ketones; (7) amidation of esters (i.e., synthesis of amides from esters and amines); (8) acylation of alcohols using esters; (9) coupling of alcohols with water to form carboxylic acids; and (10) dehydrogenation of beta-amino alcohols to form pyrazines. The present invention further relates to the novel uses of certain pyridine Ruthenium catalysts.

专利号:US-7056348-B2
优先权日:2001-04-19
标题:5-aryl-1,3,3-trimethyl-2-methylene-indoline derivatives and salts thereof, methods for the production and use of said compounds for the temporary coloration of fibers
发明人：SAUTER GUIDO; BRAUN HANS-JUERGEN; REICHLIN NADIA
权利人:WELLA AG
摘要:A method for the synthesis of 5-aryl-1,3,3,-trimethyl-2-methylene-indoline derivatives of Formula (I) or its salts of Formula (Ia) wherein 1 mole of a 5-aryl-2,3,3-trimethyl-3H-indole derivative of Formula (VII) is reacted for 1 to 44 hours at a temperature of 20° to 180° C. in an apolar, aprotic or polar, protic or polar aprotic solvent with 1 to 50 moles of a compound of Formula R1-A; new compounds of Formulas (I)/(Ia) and (V), obtainable by this method as well as an agent containing at least one compound of Formula (I)/(Ia) and a carbonyl/imine compound for dyeing keratinic fibers and a method for temporarily dyeing keratin fibers, for which the keratin fiber is dyed with the aforementioned agent and the dyeing, so obtained, is removed again at any later time by a sulfite preparation.

专利号:US-11420997-B2
优先权日:2018-04-13
标题:Peptide synthesis method
发明人：SUZUKI HIDEAKI; MUTO SUSUMU; FUJITA SHUJI; KUBO DAISUKE
权利人:JITSUBO CO LTD
摘要:The present invention has an object of shortening the process time and reducing use of a poor solvent for solidifying a carrier (Tag)-peptide component, by removing impurities without conducting solid-liquid separation (condensation, solid-liquid separation and drying operation) of a Tag-peptide component, in an Fmoc method using a Tag for liquid phase peptide synthesis. Provided is the peptide synthesis method that includes the following steps a-d: step a: a carrier-protected amino acid, carrier-protected peptide, or a carrier-protected amino acid amide, and an N-Fmoc-protected amino acid or an N-Fmoc-protected peptide are condensed in an organic solvent or a mixed solution of organic solvents, to obtain an N-Fmoc-carrier-protected peptide, step b: a water-soluble amine is added to the reaction solution after the condensation reaction, step c: the Fmoc group is deprotected from the protected amino group in the presence of a water-soluble amine, and step d: the reaction solution is neutralized by adding an acid, and further, by adding and washing with an acidic aqueous solution, then, by liquid-liquid separation an aqueous layer is removed to obtain an organic layer.